FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2117130856> ?p ?o ?g. }

• W2117130856 endingPage "1145" @default.
• W2117130856 startingPage "1140" @default.
• W2117130856 abstract "Existing data are consistent with a role for the orbitofrontal cortex (OFC) either in regulating emotion and enhancing behavioral flexibility or in updating valuations on the basis of motivational states. Here the authors show that excitotoxic lesions of OFC impair value updating but do not alter either behavioral flexibility or emotion regulation and that previous observations may have been the result of damage to nearby fiber tracts. Two ideas have dominated neuropsychology concerning the orbitofrontal cortex (OFC). One holds that OFC regulates emotion and enhances behavioral flexibility through inhibitory control. The other ascribes to OFC a role in updating valuations on the basis of current motivational states. Neuroimaging, neurophysiological and clinical observations are consistent with either or both hypotheses. Although these hypotheses are compatible in principle, we present results supporting the latter view of OFC function and arguing against the former. We found that excitotoxic, fiber-sparing lesions confined to OFC in monkeys did not alter either behavioral flexibility, as measured by object reversal learning, or emotion regulation, as assessed by fear of snakes. A follow-up experiment indicated that a previously reported loss of inhibitory control resulted from damage to nearby fiber tracts and not from OFC dysfunction. Thus, OFC has a more specialized role in reward-guided behavior and emotion than has been thought, a function that includes value updating." @default.
• W2117130856 created "2016-06-24" @default.
• W2117130856 creator A5005810000 @default.
• W2117130856 creator A5050892176 @default.
• W2117130856 creator A5064514761 @default.
• W2117130856 creator A5074065900 @default.
• W2117130856 creator A5084862732 @default.
• W2117130856 date "2013-06-23" @default.
• W2117130856 modified "2023-10-09" @default.
• W2117130856 title "Prefrontal mechanisms of behavioral flexibility, emotion regulation and value updating" @default.
• W2117130856 cites W1562703792 @default.
• W2117130856 cites W1606538720 @default.
• W2117130856 cites W1941407864 @default.
• W2117130856 cites W1969866816 @default.
• W2117130856 cites W1971078086 @default.
• W2117130856 cites W1974480006 @default.
• W2117130856 cites W1982666617 @default.
• W2117130856 cites W1984030600 @default.
• W2117130856 cites W1990068200 @default.
• W2117130856 cites W2001488773 @default.
• W2117130856 cites W2003397476 @default.
• W2117130856 cites W2006470756 @default.
• W2117130856 cites W2014284272 @default.
• W2117130856 cites W2016482990 @default.
• W2117130856 cites W2029232177 @default.
• W2117130856 cites W2030183678 @default.
• W2117130856 cites W2030634467 @default.
• W2117130856 cites W2037338304 @default.
• W2117130856 cites W2038593423 @default.
• W2117130856 cites W2041033984 @default.
• W2117130856 cites W2049156730 @default.
• W2117130856 cites W2057578219 @default.
• W2117130856 cites W2063764296 @default.
• W2117130856 cites W2072009783 @default.
• W2117130856 cites W2075850117 @default.
• W2117130856 cites W2078617766 @default.
• W2117130856 cites W2080527571 @default.
• W2117130856 cites W2097004047 @default.
• W2117130856 cites W2099925882 @default.
• W2117130856 cites W2105791633 @default.
• W2117130856 cites W2114408977 @default.
• W2117130856 cites W2115964617 @default.
• W2117130856 cites W2116390661 @default.
• W2117130856 cites W2116813115 @default.
• W2117130856 cites W2116818517 @default.
• W2117130856 cites W2119931882 @default.
• W2117130856 cites W2121370521 @default.
• W2117130856 cites W2123856966 @default.
• W2117130856 cites W2135962938 @default.
• W2117130856 cites W2138221880 @default.
• W2117130856 cites W2144725040 @default.
• W2117130856 cites W2153693979 @default.
• W2117130856 cites W2158147140 @default.
• W2117130856 cites W2160601359 @default.
• W2117130856 cites W2164750714 @default.
• W2117130856 cites W2167785873 @default.
• W2117130856 cites W2170476476 @default.
• W2117130856 cites W4238851921 @default.
• W2117130856 cites W4253401278 @default.
• W2117130856 doi "https://doi.org/10.1038/nn.3440" @default.
• W2117130856 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3733248" @default.
• W2117130856 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23792944" @default.
• W2117130856 hasPublicationYear "2013" @default.
• W2117130856 type Work @default.
• W2117130856 sameAs 2117130856 @default.
• W2117130856 citedByCount "324" @default.
• W2117130856 countsByYear W21171308562013 @default.
• W2117130856 countsByYear W21171308562014 @default.
• W2117130856 countsByYear W21171308562015 @default.
• W2117130856 countsByYear W21171308562016 @default.
• W2117130856 countsByYear W21171308562017 @default.
• W2117130856 countsByYear W21171308562018 @default.
• W2117130856 countsByYear W21171308562019 @default.
• W2117130856 countsByYear W21171308562020 @default.
• W2117130856 countsByYear W21171308562021 @default.
• W2117130856 countsByYear W21171308562022 @default.
• W2117130856 countsByYear W21171308562023 @default.
• W2117130856 crossrefType "journal-article" @default.
• W2117130856 hasAuthorship W2117130856A5005810000 @default.
• W2117130856 hasAuthorship W2117130856A5050892176 @default.
• W2117130856 hasAuthorship W2117130856A5064514761 @default.
• W2117130856 hasAuthorship W2117130856A5074065900 @default.
• W2117130856 hasAuthorship W2117130856A5084862732 @default.
• W2117130856 hasBestOaLocation W21171308562 @default.
• W2117130856 hasConcept C105795698 @default.
• W2117130856 hasConcept C14216870 @default.
• W2117130856 hasConcept C143661069 @default.
• W2117130856 hasConcept C15744967 @default.
• W2117130856 hasConcept C169760540 @default.
• W2117130856 hasConcept C169900460 @default.
• W2117130856 hasConcept C180747234 @default.
• W2117130856 hasConcept C2776559556 @default.
• W2117130856 hasConcept C2778796910 @default.
• W2117130856 hasConcept C2780598303 @default.
• W2117130856 hasConcept C2781195155 @default.
• W2117130856 hasConcept C33923547 @default.
• W2117130856 hasConcept C58693492 @default.
• W2117130856 hasConcept C66102695 @default.

• next