FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2129896901> ?p ?o ?g. }

• W2129896901 endingPage "760" @default.
• W2129896901 startingPage "749" @default.
• W2129896901 abstract "Background Vitamin D has immunomodulatory properties, such as regulation of FOXP3 expression and regulatory T-cell activity. Our aim was to investigate whether plasma 25-hydroxyvitamin D [25(OH)D] concentrations associate with the development of β-cell autoimmunity and the transcriptional activity of FOXP3 or vitamin D3 convertase gene (CYP27B1) in CD4+ memory T cells. Methods We studied 83 Finnish and 32 Estonian children participating in the DIABIMMUNE and DIPP studies. Twenty-nine Finnish and six Estonian children tested positive for at least one diabetes-associated autoantibody. The plasma concentrations of 25(OH)D and 1,25(OH)2D were analysed with an enzyme immunoassay. Gene expression of FOXP3 and CYP27B1 in the isolated CD4+ memory T cells was studied with reverse transcription quantitative polymerase chain reaction. Results Vitamin D status did not differ between subjects positive and negative for β-cell autoantibodies. Finnish children had higher vitamin D status than Estonian children (p < 0.001). FOXP3 expression was higher in Estonian CD4+ memory T-cell samples than in Finnish samples (p < 0.01) even when including in both groups only children with serum 25(OH)D concentrations in the range of 50–80 nmol/L (p < 0.001). Conclusions These findings do not support a crucial role of circulating 25(OH)D as a regulator of β-cell autoimmunity or FOXP3 expression. Copyright © 2014 John Wiley & Sons, Ltd." @default.
• W2129896901 created "2016-06-24" @default.
• W2129896901 creator A5000141478 @default.
• W2129896901 creator A5001027729 @default.
• W2129896901 creator A5004143505 @default.
• W2129896901 creator A5020918698 @default.
• W2129896901 creator A5024634851 @default.
• W2129896901 creator A5035670155 @default.
• W2129896901 creator A5038592916 @default.
• W2129896901 creator A5046739446 @default.
• W2129896901 creator A5066618511 @default.
• W2129896901 creator A5077829166 @default.
• W2129896901 creator A5088970962 @default.
• W2129896901 date "2014-11-01" @default.
• W2129896901 modified "2023-09-23" @default.
• W2129896901 title "No association between vitamin D and β-cell autoimmunity in Finnish and Estonian children" @default.
• W2129896901 cites W1539668795 @default.
• W2129896901 cites W1548811205 @default.
• W2129896901 cites W1866685620 @default.
• W2129896901 cites W1968590906 @default.
• W2129896901 cites W1971781183 @default.
• W2129896901 cites W1978110685 @default.
• W2129896901 cites W1979896023 @default.
• W2129896901 cites W1983725843 @default.
• W2129896901 cites W1984909066 @default.
• W2129896901 cites W1993462634 @default.
• W2129896901 cites W1996305789 @default.
• W2129896901 cites W2006083207 @default.
• W2129896901 cites W2007331929 @default.
• W2129896901 cites W2009261961 @default.
• W2129896901 cites W2013605176 @default.
• W2129896901 cites W2018669479 @default.
• W2129896901 cites W2019972832 @default.
• W2129896901 cites W2036604633 @default.
• W2129896901 cites W2051625108 @default.
• W2129896901 cites W2067253042 @default.
• W2129896901 cites W2067958095 @default.
• W2129896901 cites W2073853823 @default.
• W2129896901 cites W2081722110 @default.
• W2129896901 cites W2095483193 @default.
• W2129896901 cites W2098566344 @default.
• W2129896901 cites W2106044877 @default.
• W2129896901 cites W2108825111 @default.
• W2129896901 cites W2110153176 @default.
• W2129896901 cites W2114122082 @default.
• W2129896901 cites W2121250603 @default.
• W2129896901 cites W2125404283 @default.
• W2129896901 cites W2127755180 @default.
• W2129896901 cites W2139019810 @default.
• W2129896901 cites W2139947754 @default.
• W2129896901 cites W2142286205 @default.
• W2129896901 cites W2143565640 @default.
• W2129896901 cites W2159638886 @default.
• W2129896901 doi "https://doi.org/10.1002/dmrr.2550" @default.
• W2129896901 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24692218" @default.
• W2129896901 hasPublicationYear "2014" @default.
• W2129896901 type Work @default.
• W2129896901 sameAs 2129896901 @default.
• W2129896901 citedByCount "20" @default.
• W2129896901 countsByYear W21298969012015 @default.
• W2129896901 countsByYear W21298969012016 @default.
• W2129896901 countsByYear W21298969012017 @default.
• W2129896901 countsByYear W21298969012018 @default.
• W2129896901 countsByYear W21298969012019 @default.
• W2129896901 countsByYear W21298969012020 @default.
• W2129896901 countsByYear W21298969012021 @default.
• W2129896901 countsByYear W21298969012022 @default.
• W2129896901 crossrefType "journal-article" @default.
• W2129896901 hasAuthorship W2129896901A5000141478 @default.
• W2129896901 hasAuthorship W2129896901A5001027729 @default.
• W2129896901 hasAuthorship W2129896901A5004143505 @default.
• W2129896901 hasAuthorship W2129896901A5020918698 @default.
• W2129896901 hasAuthorship W2129896901A5024634851 @default.
• W2129896901 hasAuthorship W2129896901A5035670155 @default.
• W2129896901 hasAuthorship W2129896901A5038592916 @default.
• W2129896901 hasAuthorship W2129896901A5046739446 @default.
• W2129896901 hasAuthorship W2129896901A5066618511 @default.
• W2129896901 hasAuthorship W2129896901A5077829166 @default.
• W2129896901 hasAuthorship W2129896901A5088970962 @default.
• W2129896901 hasConcept C124490489 @default.
• W2129896901 hasConcept C126322002 @default.
• W2129896901 hasConcept C134018914 @default.
• W2129896901 hasConcept C138885662 @default.
• W2129896901 hasConcept C159654299 @default.
• W2129896901 hasConcept C185592680 @default.
• W2129896901 hasConcept C203014093 @default.
• W2129896901 hasConcept C2776090121 @default.
• W2129896901 hasConcept C2776092919 @default.
• W2129896901 hasConcept C2779727006 @default.
• W2129896901 hasConcept C2780130043 @default.
• W2129896901 hasConcept C41895202 @default.
• W2129896901 hasConcept C71924100 @default.
• W2129896901 hasConcept C86803240 @default.
• W2129896901 hasConcept C8891405 @default.
• W2129896901 hasConceptScore W2129896901C124490489 @default.
• W2129896901 hasConceptScore W2129896901C126322002 @default.
• W2129896901 hasConceptScore W2129896901C134018914 @default.
• W2129896901 hasConceptScore W2129896901C138885662 @default.

• next