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• W2135758510 abstract "The purpose of this work is to assess the additional benefit of MRI-based morphology and quantification of contrast enhancement in the differential diagnosis of sub-1cm breast lesions. Forty-three women with suspected breast cancer were examined using X-ray mammography, ultrasound mammography, and MRI. Dynamic contrast imaging was performed and relative enhancement at various time-points was calculated. The dynamic data was also processed using a two-compartment pharmacokinetic model. Radiological interpretation of high-resolution post-contrast images revealed a similar accuracy (69%) compared to X-ray mammography (69%) and ultrasound mammography (67%). The best individual parameter calculated from the dynamic images was found to be the exchange rate constant which revealed a diagnostic accuracy of 0.74 +/- 0.08. When information from the post-contrast images and dynamic data was combined in a logistic regression model a diagnostic accuracy of 0.92 +/- 0.03 was achieved. In conclusion, MR imaging of small breast lesions is feasible and the incorporation of quantitative MR derived parameters is beneficial." @default.
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• W2135758510 date "2004-04-01" @default.
• W2135758510 modified "2023-10-14" @default.
• W2135758510 title "Differentiation of benign and malignant sub-1 cm breast lesions using dynamic contrast enhanced MRI" @default.
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• W2135758510 doi "https://doi.org/10.1016/j.breast.2003.10.002" @default.
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