Matches in SemOpenAlex for { <https://semopenalex.org/work/W2139898483> ?p ?o ?g. }
- W2139898483 abstract "The importance of neu in breast cancer provided the rationale and impetus for developing agents that targeted the receptor. Proof of therapeutic principle was subsequently established with trastuzumab. Although not minimal, the improved clinical outcomes with the antibody were somewhat counterbalanced by disease relapses which occurred in advanced and adjuvant therapy settings. What this observation suggests is that while tumor response may be due principally to uncoupling the link between cell surface message reception and nuclear gene expression, disease progression appears to involve a re-programmable cellular mainframe that enables alternative tumor growth and survival pathways to become operational. The goal of this paper is to meld biological and therapeutic concepts that have resulted in further advances in the treatment of neu-amplified breast cancers." @default.
- W2139898483 created "2016-06-24" @default.
- W2139898483 creator A5010494915 @default.
- W2139898483 creator A5090272219 @default.
- W2139898483 date "2013-01-01" @default.
- W2139898483 modified "2023-09-26" @default.
- W2139898483 title "Life after Trastuzumab: Neu Strategies for HER2-positive Breast Cancer" @default.
- W2139898483 cites W1532588163 @default.
- W2139898483 cites W1606090394 @default.
- W2139898483 cites W1804903119 @default.
- W2139898483 cites W1812955231 @default.
- W2139898483 cites W1855853533 @default.
- W2139898483 cites W1857239756 @default.
- W2139898483 cites W1893360284 @default.
- W2139898483 cites W1973033337 @default.
- W2139898483 cites W1975348357 @default.
- W2139898483 cites W1980499243 @default.
- W2139898483 cites W1983865998 @default.
- W2139898483 cites W1984093355 @default.
- W2139898483 cites W1987117672 @default.
- W2139898483 cites W1992127683 @default.
- W2139898483 cites W1999513758 @default.
- W2139898483 cites W2001627828 @default.
- W2139898483 cites W2012784647 @default.
- W2139898483 cites W2012883222 @default.
- W2139898483 cites W2013669698 @default.
- W2139898483 cites W2014053430 @default.
- W2139898483 cites W2014457594 @default.
- W2139898483 cites W2019895529 @default.
- W2139898483 cites W2024651005 @default.
- W2139898483 cites W2033488181 @default.
- W2139898483 cites W2034801324 @default.
- W2139898483 cites W2037769103 @default.
- W2139898483 cites W2040142253 @default.
- W2139898483 cites W2043970203 @default.
- W2139898483 cites W2045134790 @default.
- W2139898483 cites W2057458801 @default.
- W2139898483 cites W2080518844 @default.
- W2139898483 cites W2082431893 @default.
- W2139898483 cites W2088145034 @default.
- W2139898483 cites W2093189266 @default.
- W2139898483 cites W2094477446 @default.
- W2139898483 cites W2096111541 @default.
- W2139898483 cites W2097698108 @default.
- W2139898483 cites W2100794900 @default.
- W2139898483 cites W2101299592 @default.
- W2139898483 cites W2101824720 @default.
- W2139898483 cites W2104239861 @default.
- W2139898483 cites W2105516763 @default.
- W2139898483 cites W2106660927 @default.
- W2139898483 cites W2107426197 @default.
- W2139898483 cites W2110444464 @default.
- W2139898483 cites W2111578514 @default.
- W2139898483 cites W2111941775 @default.
- W2139898483 cites W2114195503 @default.
- W2139898483 cites W2114282952 @default.
- W2139898483 cites W2114286868 @default.
- W2139898483 cites W2115007832 @default.
- W2139898483 cites W2115100262 @default.
- W2139898483 cites W2115330997 @default.
- W2139898483 cites W2123591186 @default.
- W2139898483 cites W2128307445 @default.
- W2139898483 cites W2128402413 @default.
- W2139898483 cites W2130900820 @default.
- W2139898483 cites W2132152535 @default.
- W2139898483 cites W2136704455 @default.
- W2139898483 cites W2137086207 @default.
- W2139898483 cites W2139444209 @default.
- W2139898483 cites W2141232624 @default.
- W2139898483 cites W2141346487 @default.
- W2139898483 cites W2142752401 @default.
- W2139898483 cites W2146384083 @default.
- W2139898483 cites W2147761019 @default.
- W2139898483 cites W2149908785 @default.
- W2139898483 cites W2149952977 @default.
- W2139898483 cites W2154246971 @default.
- W2139898483 cites W2155794195 @default.
- W2139898483 cites W2159013299 @default.
- W2139898483 cites W2159967578 @default.
- W2139898483 cites W2166199281 @default.
- W2139898483 cites W2168814163 @default.
- W2139898483 cites W2180005201 @default.
- W2139898483 cites W2289352020 @default.
- W2139898483 cites W2318605753 @default.
- W2139898483 cites W2338405699 @default.
- W2139898483 cites W3149591292 @default.
- W2139898483 cites W96342227 @default.
- W2139898483 cites W3081258301 @default.
- W2139898483 doi "https://doi.org/10.5281/zenodo.810572" @default.
- W2139898483 hasPublicationYear "2013" @default.
- W2139898483 type Work @default.
- W2139898483 sameAs 2139898483 @default.
- W2139898483 citedByCount "0" @default.
- W2139898483 crossrefType "journal-article" @default.
- W2139898483 hasAuthorship W2139898483A5010494915 @default.
- W2139898483 hasAuthorship W2139898483A5090272219 @default.
- W2139898483 hasBestOaLocation W21398984831 @default.
- W2139898483 hasConcept C121608353 @default.
- W2139898483 hasConcept C126322002 @default.
- W2139898483 hasConcept C143998085 @default.