FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2141036287> ?p ?o ?g. }

• W2141036287 endingPage "1801" @default.
• W2141036287 startingPage "1795" @default.
• W2141036287 abstract "OBJECTIVE: Visual contrast detection has been reported in some studies to be normal in schizophrenia patients, but in other studies impairments have been reported. Because contrast detection in the visual processing system is mediated by dopamine, and because the pharmacotherapy of schizophrenia involves blocking dopamine postsynaptic receptor sites, the authors investigated the effects of dopamine-blocking antipsychotic drugs on visual contrast detection in schizophrenia. METHOD: Visual contrast detection thresholds were measured in healthy subjects and schizophrenia patients receiving typical and atypical antipsychotic drugs; a two-alternative, forced-choice psychophysical method was used. Also included were six patients receiving no antipsychotic treatment as well as clinically unaffected first-degree relatives of the schizophrenia patients. RESULTS: Patients receiving atypical antipsychotic drugs showed unimpaired visual contrast detection, those given typical antipsychotic drugs exhibited higher visual contrast detection thresholds, and the unmedicated schizophrenic patients showed visual contrast detection thresholds significantly below those of healthy subjects. CONCLUSIONS: Dopamine modulation via D2 receptor blockade affects sensory processes in schizophrenia, shifting visual contrast detection from hypersensitivity in the unmedicated state to normal and even to hyposensitive levels. Thus, antipsychotic drug treatment may account for the inconsistent reports concerning visual contrast detection in schizophrenia." @default.
• W2141036287 created "2016-06-24" @default.
• W2141036287 creator A5014995330 @default.
• W2141036287 creator A5018056546 @default.
• W2141036287 creator A5026718860 @default.
• W2141036287 creator A5054018011 @default.
• W2141036287 creator A5060314627 @default.
• W2141036287 creator A5085918263 @default.
• W2141036287 date "2003-10-01" @default.
• W2141036287 modified "2023-09-25" @default.
• W2141036287 title "Effects of Typical, Atypical, and No Antipsychotic Drugs on Visual Contrast Detection in Schizophrenia" @default.
• W2141036287 cites W1485901143 @default.
• W2141036287 cites W1968190574 @default.
• W2141036287 cites W1969334748 @default.
• W2141036287 cites W1973315113 @default.
• W2141036287 cites W1995778321 @default.
• W2141036287 cites W1997939697 @default.
• W2141036287 cites W2006289228 @default.
• W2141036287 cites W2008998885 @default.
• W2141036287 cites W2020844317 @default.
• W2141036287 cites W2028954909 @default.
• W2141036287 cites W2048405858 @default.
• W2141036287 cites W2050185241 @default.
• W2141036287 cites W2050764161 @default.
• W2141036287 cites W2074888284 @default.
• W2141036287 cites W2080678410 @default.
• W2141036287 cites W2087369617 @default.
• W2141036287 cites W2088845557 @default.
• W2141036287 cites W2093978889 @default.
• W2141036287 cites W2099085951 @default.
• W2141036287 cites W2101839239 @default.
• W2141036287 cites W2137407494 @default.
• W2141036287 cites W2138340806 @default.
• W2141036287 cites W2139704528 @default.
• W2141036287 cites W2398703169 @default.
• W2141036287 cites W2419085840 @default.
• W2141036287 cites W34287105 @default.
• W2141036287 cites W366694848 @default.
• W2141036287 doi "https://doi.org/10.1176/appi.ajp.160.10.1795" @default.
• W2141036287 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14514493" @default.
• W2141036287 hasPublicationYear "2003" @default.
• W2141036287 type Work @default.
• W2141036287 sameAs 2141036287 @default.
• W2141036287 citedByCount "91" @default.
• W2141036287 countsByYear W21410362872012 @default.
• W2141036287 countsByYear W21410362872013 @default.
• W2141036287 countsByYear W21410362872014 @default.
• W2141036287 countsByYear W21410362872015 @default.
• W2141036287 countsByYear W21410362872016 @default.
• W2141036287 countsByYear W21410362872017 @default.
• W2141036287 countsByYear W21410362872018 @default.
• W2141036287 countsByYear W21410362872019 @default.
• W2141036287 countsByYear W21410362872020 @default.
• W2141036287 countsByYear W21410362872021 @default.
• W2141036287 countsByYear W21410362872022 @default.
• W2141036287 countsByYear W21410362872023 @default.
• W2141036287 crossrefType "journal-article" @default.
• W2141036287 hasAuthorship W2141036287A5014995330 @default.
• W2141036287 hasAuthorship W2141036287A5018056546 @default.
• W2141036287 hasAuthorship W2141036287A5026718860 @default.
• W2141036287 hasAuthorship W2141036287A5054018011 @default.
• W2141036287 hasAuthorship W2141036287A5060314627 @default.
• W2141036287 hasAuthorship W2141036287A5085918263 @default.
• W2141036287 hasConcept C118552586 @default.
• W2141036287 hasConcept C154945302 @default.
• W2141036287 hasConcept C15744967 @default.
• W2141036287 hasConcept C169760540 @default.
• W2141036287 hasConcept C2775870346 @default.
• W2141036287 hasConcept C2776412080 @default.
• W2141036287 hasConcept C2776502983 @default.
• W2141036287 hasConcept C2776921671 @default.
• W2141036287 hasConcept C2779727114 @default.
• W2141036287 hasConcept C2780494398 @default.
• W2141036287 hasConcept C2780864610 @default.
• W2141036287 hasConcept C41008148 @default.
• W2141036287 hasConcept C44208683 @default.
• W2141036287 hasConcept C513476851 @default.
• W2141036287 hasConcept C548259974 @default.
• W2141036287 hasConcept C71924100 @default.
• W2141036287 hasConceptScore W2141036287C118552586 @default.
• W2141036287 hasConceptScore W2141036287C154945302 @default.
• W2141036287 hasConceptScore W2141036287C15744967 @default.
• W2141036287 hasConceptScore W2141036287C169760540 @default.
• W2141036287 hasConceptScore W2141036287C2775870346 @default.
• W2141036287 hasConceptScore W2141036287C2776412080 @default.
• W2141036287 hasConceptScore W2141036287C2776502983 @default.
• W2141036287 hasConceptScore W2141036287C2776921671 @default.
• W2141036287 hasConceptScore W2141036287C2779727114 @default.
• W2141036287 hasConceptScore W2141036287C2780494398 @default.
• W2141036287 hasConceptScore W2141036287C2780864610 @default.
• W2141036287 hasConceptScore W2141036287C41008148 @default.
• W2141036287 hasConceptScore W2141036287C44208683 @default.
• W2141036287 hasConceptScore W2141036287C513476851 @default.
• W2141036287 hasConceptScore W2141036287C548259974 @default.
• W2141036287 hasConceptScore W2141036287C71924100 @default.
• W2141036287 hasIssue "10" @default.
• W2141036287 hasLocation W21410362871 @default.
• W2141036287 hasLocation W21410362872 @default.

• next