FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2156770798> ?p ?o ?g. }

• W2156770798 abstract "GPs are urged to prescribe antibiotics less frequently, despite lack of evidence linking reduced antibiotic prescribing with reductions in resistance at a local level.To investigate associations between changes in antibiotic dispensing and changes in antibiotic resistance at general-practice level.Seven-year study of dispensed antibiotics and antibiotic resistance in coliform isolates from urine samples routinely submitted from general practice.General practices in Wales.Multilevel modelling of trends in resistance to ampicillin and trimethoprim, and changes in practice total antibiotic dispensing and amoxicillin and trimethoprim dispensing.The primary analysis included data on 164 225 coliform isolates from urine samples submitted from 240 general practices over the 7-year study period. These practices served a population of 1.7 million patients. The quartile of practices that had the greatest decrease in total antibiotic dispensing demonstrated a 5.2% reduction in ampicillin resistance over the 7-year period with changes of 0.4%, 2.4%, and -0.3% in the other three quartiles. There was a statistically significant overall decrease in ampicillin resistance of 1.03% (95% confidence interval [CI] = 0.37 to 1.67%) per decrease of 50 amoxicillin items dispensed per 1000 patients per annum. There were also significant reductions in trimethoprim resistance in the two quartiles of practices that reduced total antibiotic dispensing most compared with those that reduced it least, with an overall decrease in trimethoprim resistance of 1.08% (95% CI = 0.065 to 2.10%) per decrease of 20 trimethoprim items dispensed per 1000 patients per annum. Main findings were confirmed by secondary analyses of 256 370 isolates from 527 practices that contributed data at some point during the study period.Reducing antibiotic dispensing at general-practice level is associated with reduced local antibiotic resistance. These findings should further encourage clinicians and patients to use antibiotics conservatively." @default.
• W2156770798 created "2016-06-24" @default.
• W2156770798 creator A5017547539 @default.
• W2156770798 creator A5018882595 @default.
• W2156770798 creator A5022797716 @default.
• W2156770798 creator A5026663108 @default.
• W2156770798 creator A5041616782 @default.
• W2156770798 creator A5046926803 @default.
• W2156770798 creator A5056377500 @default.
• W2156770798 creator A5058552951 @default.
• W2156770798 creator A5069343194 @default.
• W2156770798 date "2007-10-01" @default.
• W2156770798 modified "2023-10-17" @default.
• W2156770798 title "Containing antibiotic resistance: decreased antibiotic-resistant coliform urinary tract infections with reduction in antibiotic prescribing by general practices." @default.
• W2156770798 cites W1496200171 @default.
• W2156770798 cites W1504556821 @default.
• W2156770798 cites W1538455569 @default.
• W2156770798 cites W1548606575 @default.
• W2156770798 cites W1552893499 @default.
• W2156770798 cites W1824052742 @default.
• W2156770798 cites W1969062801 @default.
• W2156770798 cites W1971724552 @default.
• W2156770798 cites W1975555110 @default.
• W2156770798 cites W1986768368 @default.
• W2156770798 cites W2022927810 @default.
• W2156770798 cites W2026215081 @default.
• W2156770798 cites W2027411995 @default.
• W2156770798 cites W2032843976 @default.
• W2156770798 cites W2046220565 @default.
• W2156770798 cites W2055470593 @default.
• W2156770798 cites W2055750915 @default.
• W2156770798 cites W2069034102 @default.
• W2156770798 cites W2079785911 @default.
• W2156770798 cites W2094718844 @default.
• W2156770798 cites W2108505069 @default.
• W2156770798 cites W2110565577 @default.
• W2156770798 cites W2114293981 @default.
• W2156770798 cites W2118728578 @default.
• W2156770798 cites W2119546919 @default.
• W2156770798 cites W2120949603 @default.
• W2156770798 cites W2121259919 @default.
• W2156770798 cites W2128194846 @default.
• W2156770798 cites W2138685072 @default.
• W2156770798 cites W2139393237 @default.
• W2156770798 cites W2141559306 @default.
• W2156770798 cites W2141878952 @default.
• W2156770798 cites W2143697487 @default.
• W2156770798 cites W2148030279 @default.
• W2156770798 cites W2150546489 @default.
• W2156770798 cites W2165296911 @default.
• W2156770798 cites W2169934070 @default.
• W2156770798 cites W2171609823 @default.
• W2156770798 cites W2321640152 @default.
• W2156770798 cites W26774890 @default.
• W2156770798 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2151810" @default.
• W2156770798 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17925135" @default.
• W2156770798 hasPublicationYear "2007" @default.
• W2156770798 type Work @default.
• W2156770798 sameAs 2156770798 @default.
• W2156770798 citedByCount "50" @default.
• W2156770798 countsByYear W21567707982012 @default.
• W2156770798 countsByYear W21567707982013 @default.
• W2156770798 countsByYear W21567707982014 @default.
• W2156770798 countsByYear W21567707982015 @default.
• W2156770798 countsByYear W21567707982016 @default.
• W2156770798 countsByYear W21567707982017 @default.
• W2156770798 countsByYear W21567707982018 @default.
• W2156770798 countsByYear W21567707982019 @default.
• W2156770798 countsByYear W21567707982020 @default.
• W2156770798 countsByYear W21567707982022 @default.
• W2156770798 crossrefType "journal-article" @default.
• W2156770798 hasAuthorship W2156770798A5017547539 @default.
• W2156770798 hasAuthorship W2156770798A5018882595 @default.
• W2156770798 hasAuthorship W2156770798A5022797716 @default.
• W2156770798 hasAuthorship W2156770798A5026663108 @default.
• W2156770798 hasAuthorship W2156770798A5041616782 @default.
• W2156770798 hasAuthorship W2156770798A5046926803 @default.
• W2156770798 hasAuthorship W2156770798A5056377500 @default.
• W2156770798 hasAuthorship W2156770798A5058552951 @default.
• W2156770798 hasAuthorship W2156770798A5069343194 @default.
• W2156770798 hasConcept C126322002 @default.
• W2156770798 hasConcept C2776021129 @default.
• W2156770798 hasConcept C2777629877 @default.
• W2156770798 hasConcept C2779425571 @default.
• W2156770798 hasConcept C2779708577 @default.
• W2156770798 hasConcept C2780728791 @default.
• W2156770798 hasConcept C2908647359 @default.
• W2156770798 hasConcept C44249647 @default.
• W2156770798 hasConcept C501593827 @default.
• W2156770798 hasConcept C68443243 @default.
• W2156770798 hasConcept C71924100 @default.
• W2156770798 hasConcept C86803240 @default.
• W2156770798 hasConcept C89423630 @default.
• W2156770798 hasConcept C94665300 @default.
• W2156770798 hasConcept C99454951 @default.
• W2156770798 hasConceptScore W2156770798C126322002 @default.
• W2156770798 hasConceptScore W2156770798C2776021129 @default.
• W2156770798 hasConceptScore W2156770798C2777629877 @default.
• W2156770798 hasConceptScore W2156770798C2779425571 @default.
• W2156770798 hasConceptScore W2156770798C2779708577 @default.

• next