FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2156854989> ?p ?o ?g. }

• W2156854989 endingPage "211" @default.
• W2156854989 startingPage "211" @default.
• W2156854989 abstract "The Red Queen Hypothesis (RQH) suggests that the coevolutionary dynamics of host-parasite systems can generate selection for increased host recombination. Since host-parasite interactions often have a strong genetic basis, recombination between different hosts can increase the fraction of novel and potentially resistant offspring genotypes. A prerequisite for this mechanism is that host-parasite interactions generate persistent oscillations of linkage disequilibria (LD). We use deterministic and stochastic models to investigate the persistence of LD oscillations and its impact on the RQH. The standard models of the Red Queen dynamics exhibit persistent LD oscillations under most circumstances. Here, we show that altering the standard model from discrete to continuous time or from simultaneous to sequential updating results in damped LD oscillations. This suggests that LD oscillations are structurally not robust. We then show that in a stochastic regime, drift can counteract this dampening and maintain the oscillations. In addition, we show that the amplitude of the oscillations and therefore the strength of the resulting selection for or against recombination are inversely proportional to the size of the (host) population. We find that host parasite-interactions cannot generally maintain oscillations in the absence of drift. As a consequence, the RQH can strongly depend on population size and should therefore not be interpreted as a purely deterministic hypothesis." @default.
• W2156854989 created "2016-06-24" @default.
• W2156854989 creator A5010649096 @default.
• W2156854989 creator A5054236642 @default.
• W2156854989 creator A5069244385 @default.
• W2156854989 date "2007-01-01" @default.
• W2156854989 modified "2023-09-27" @default.
• W2156854989 title "The Red Queen and the persistence of linkage-disequilibrium oscillations in finite and infinite populations" @default.
• W2156854989 cites W1523843460 @default.
• W2156854989 cites W1605803370 @default.
• W2156854989 cites W1885919887 @default.
• W2156854989 cites W1999614046 @default.
• W2156854989 cites W2039079745 @default.
• W2156854989 cites W2052161433 @default.
• W2156854989 cites W2056362696 @default.
• W2156854989 cites W2079803956 @default.
• W2156854989 cites W2112294153 @default.
• W2156854989 cites W2115339120 @default.
• W2156854989 cites W2123770696 @default.
• W2156854989 cites W2139260005 @default.
• W2156854989 cites W2145250129 @default.
• W2156854989 cites W2170802338 @default.
• W2156854989 cites W2172253900 @default.
• W2156854989 cites W2177648269 @default.
• W2156854989 cites W2364331122 @default.
• W2156854989 doi "https://doi.org/10.1186/1471-2148-7-211" @default.
• W2156854989 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2198919" @default.
• W2156854989 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17986336" @default.
• W2156854989 hasPublicationYear "2007" @default.
• W2156854989 type Work @default.
• W2156854989 sameAs 2156854989 @default.
• W2156854989 citedByCount "41" @default.
• W2156854989 countsByYear W21568549892012 @default.
• W2156854989 countsByYear W21568549892014 @default.
• W2156854989 countsByYear W21568549892015 @default.
• W2156854989 countsByYear W21568549892017 @default.
• W2156854989 countsByYear W21568549892018 @default.
• W2156854989 countsByYear W21568549892019 @default.
• W2156854989 countsByYear W21568549892020 @default.
• W2156854989 countsByYear W21568549892021 @default.
• W2156854989 countsByYear W21568549892022 @default.
• W2156854989 countsByYear W21568549892023 @default.
• W2156854989 crossrefType "journal-article" @default.
• W2156854989 hasAuthorship W2156854989A5010649096 @default.
• W2156854989 hasAuthorship W2156854989A5054236642 @default.
• W2156854989 hasAuthorship W2156854989A5069244385 @default.
• W2156854989 hasBestOaLocation W21568549891 @default.
• W2156854989 hasConcept C104317684 @default.
• W2156854989 hasConcept C121332964 @default.
• W2156854989 hasConcept C121864883 @default.
• W2156854989 hasConcept C126831891 @default.
• W2156854989 hasConcept C127413603 @default.
• W2156854989 hasConcept C144024400 @default.
• W2156854989 hasConcept C149923435 @default.
• W2156854989 hasConcept C154945302 @default.
• W2156854989 hasConcept C156695909 @default.
• W2156854989 hasConcept C180754005 @default.
• W2156854989 hasConcept C187320778 @default.
• W2156854989 hasConcept C197754878 @default.
• W2156854989 hasConcept C2781009140 @default.
• W2156854989 hasConcept C2908647359 @default.
• W2156854989 hasConcept C33009525 @default.
• W2156854989 hasConcept C35605836 @default.
• W2156854989 hasConcept C41008148 @default.
• W2156854989 hasConcept C54355233 @default.
• W2156854989 hasConcept C68873052 @default.
• W2156854989 hasConcept C78458016 @default.
• W2156854989 hasConcept C80990810 @default.
• W2156854989 hasConcept C81917197 @default.
• W2156854989 hasConcept C86803240 @default.
• W2156854989 hasConceptScore W2156854989C104317684 @default.
• W2156854989 hasConceptScore W2156854989C121332964 @default.
• W2156854989 hasConceptScore W2156854989C121864883 @default.
• W2156854989 hasConceptScore W2156854989C126831891 @default.
• W2156854989 hasConceptScore W2156854989C127413603 @default.
• W2156854989 hasConceptScore W2156854989C144024400 @default.
• W2156854989 hasConceptScore W2156854989C149923435 @default.
• W2156854989 hasConceptScore W2156854989C154945302 @default.
• W2156854989 hasConceptScore W2156854989C156695909 @default.
• W2156854989 hasConceptScore W2156854989C180754005 @default.
• W2156854989 hasConceptScore W2156854989C187320778 @default.
• W2156854989 hasConceptScore W2156854989C197754878 @default.
• W2156854989 hasConceptScore W2156854989C2781009140 @default.
• W2156854989 hasConceptScore W2156854989C2908647359 @default.
• W2156854989 hasConceptScore W2156854989C33009525 @default.
• W2156854989 hasConceptScore W2156854989C35605836 @default.
• W2156854989 hasConceptScore W2156854989C41008148 @default.
• W2156854989 hasConceptScore W2156854989C54355233 @default.
• W2156854989 hasConceptScore W2156854989C68873052 @default.
• W2156854989 hasConceptScore W2156854989C78458016 @default.
• W2156854989 hasConceptScore W2156854989C80990810 @default.
• W2156854989 hasConceptScore W2156854989C81917197 @default.
• W2156854989 hasConceptScore W2156854989C86803240 @default.
• W2156854989 hasIssue "1" @default.
• W2156854989 hasLocation W21568549891 @default.
• W2156854989 hasLocation W21568549892 @default.
• W2156854989 hasLocation W21568549893 @default.
• W2156854989 hasLocation W21568549894 @default.

• next