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- W2157183777 endingPage "1118" @default.
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- W2157183777 abstract "The immune system, like many systems responsive to specific stimuli, requires feedback regulation. The key regulatory element determining antigen-specific responsiveness is the effector T helper. As the response tends to overshoot, a feedback control of the magnitude of the response is critical to avoid immunopathology. This is the proposed role of the effector T suppressor (Ts). The reasons for this interpretation of the data are discussed as are the reasons that the competing postulate is ruled out, namely that Ts function in determining the self-non-self-discrimination. The regulatory T cell family consists of two lineages, T helpers and Ts. Differentiated derivatives of the T helper lineage drive the expression and amplification of specific classes of defensive effector cells. Ts feedback to limit the magnitude of the process so that debilitating immunopathology is acceptably infrequent." @default.
- W2157183777 created "2016-06-24" @default.
- W2157183777 creator A5017154394 @default.
- W2157183777 date "2008-07-03" @default.
- W2157183777 modified "2023-10-17" @default.
- W2157183777 title "What roles do regulatory T cells play in the control of the adaptive immune response?" @default.
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- W2157183777 cites W1966656698 @default.
- W2157183777 cites W1968459329 @default.
- W2157183777 cites W1971083544 @default.
- W2157183777 cites W1972863671 @default.
- W2157183777 cites W1973917563 @default.
- W2157183777 cites W1975837651 @default.
- W2157183777 cites W1976104266 @default.
- W2157183777 cites W1978292183 @default.
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- W2157183777 doi "https://doi.org/10.1093/intimm/dxn088" @default.
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