FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2163070086> ?p ?o ?g. }

• W2163070086 endingPage "3039" @default.
• W2163070086 startingPage "3029" @default.
• W2163070086 abstract "The head and neck lymph nodes (LN)--or cranial, oral, and nasal-associated lymphoid tissue (CONALT)--help disseminate activated lymphocytes to produce salivary immune responses, especially after intranasal immunization. To elucidate the mechanisms that induce immunity at these sites, we investigated the interactions between addressins and homing-receptors that allow for lymphocyte binding to high endothelial venules (HEV) of CONALT. In vivo lymphocyte trafficking to CONALT was mediated primarily through interactions between peripheral node addressin (PNAd) and L-selectin, whereas interactions between mucosal addressin cell adhesion molecule-1 (MAdCAM-1) and alpha 4 beta 7 played a role in retention in cervical LN (CLN). Upon immunofluorescent staining for PNAd and MAdCAM-1, nearly all HEV in CONALT expressed PNAd, with varying MAdCAM-1 expression among these LN. The parotid gland LN (PRLN) and submaxillary gland LN (SMLN) rely exclusively upon PNAd-L-selectin interactions for naive-lymphocyte binding, whereas the CLN utilize PNAd-L-selectin interactions and MAdCAM-1-alpha 4 beta 7 interactions for binding. Intense staining of non-HEV-expressed vascular cell adhesion molecule-1 (VCAM-1) was observed in PRLN, whereas SMLN and CLN displayed less VCAM-1 but showed intense staining for diffuse MAdCAM-1. This study suggests that though PNAd-L-selectin interactions play an important role in the trafficking of lymphocytes throughout CONALT, varying MAdCAM-1 and VCAM-1 addressin expression and usage impart important differences among the PRLN, SMLN, and CLN." @default.
• W2163070086 created "2016-06-24" @default.
• W2163070086 creator A5044256453 @default.
• W2163070086 creator A5057356831 @default.
• W2163070086 creator A5084118534 @default.
• W2163070086 date "2002-11-01" @default.
• W2163070086 modified "2023-09-26" @default.
• W2163070086 title "Mucosal addressin expression and binding-interactions with naive lymphocytes vary among the cranial, oral, and nasal-associated lymphoid tissues" @default.
• W2163070086 cites W1570367374 @default.
• W2163070086 cites W1573082208 @default.
• W2163070086 cites W1575253744 @default.
• W2163070086 cites W1579391661 @default.
• W2163070086 cites W1588940854 @default.
• W2163070086 cites W168699217 @default.
• W2163070086 cites W1791802991 @default.
• W2163070086 cites W1932606735 @default.
• W2163070086 cites W1938534234 @default.
• W2163070086 cites W1974267729 @default.
• W2163070086 cites W1980667816 @default.
• W2163070086 cites W2000156766 @default.
• W2163070086 cites W2012839093 @default.
• W2163070086 cites W2023353270 @default.
• W2163070086 cites W2039638671 @default.
• W2163070086 cites W2045219244 @default.
• W2163070086 cites W2046972996 @default.
• W2163070086 cites W2050329759 @default.
• W2163070086 cites W2051077211 @default.
• W2163070086 cites W2061140050 @default.
• W2163070086 cites W2085233986 @default.
• W2163070086 cites W2085875957 @default.
• W2163070086 cites W2103826558 @default.
• W2163070086 cites W2126088081 @default.
• W2163070086 cites W2128509983 @default.
• W2163070086 cites W2131260695 @default.
• W2163070086 cites W2139865477 @default.
• W2163070086 cites W2143105928 @default.
• W2163070086 cites W2144240640 @default.
• W2163070086 cites W2147103967 @default.
• W2163070086 cites W2148997371 @default.
• W2163070086 cites W2151164451 @default.
• W2163070086 cites W2155074182 @default.
• W2163070086 cites W2159588837 @default.
• W2163070086 cites W2160741006 @default.
• W2163070086 cites W2163789996 @default.
• W2163070086 cites W2292337439 @default.
• W2163070086 cites W2401096231 @default.
• W2163070086 cites W2417660892 @default.
• W2163070086 cites W2493620918 @default.
• W2163070086 cites W89417188 @default.
• W2163070086 cites W1549164741 @default.
• W2163070086 doi "https://doi.org/10.1002/1521-4141(200211)32:11<3029::aid-immu3029>3.0.co;2-9" @default.
• W2163070086 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12385022" @default.
• W2163070086 hasPublicationYear "2002" @default.
• W2163070086 type Work @default.
• W2163070086 sameAs 2163070086 @default.
• W2163070086 citedByCount "35" @default.
• W2163070086 countsByYear W21630700862012 @default.
• W2163070086 countsByYear W21630700862014 @default.
• W2163070086 countsByYear W21630700862015 @default.
• W2163070086 countsByYear W21630700862018 @default.
• W2163070086 countsByYear W21630700862020 @default.
• W2163070086 countsByYear W21630700862021 @default.
• W2163070086 countsByYear W21630700862022 @default.
• W2163070086 crossrefType "journal-article" @default.
• W2163070086 hasAuthorship W2163070086A5044256453 @default.
• W2163070086 hasAuthorship W2163070086A5057356831 @default.
• W2163070086 hasAuthorship W2163070086A5084118534 @default.
• W2163070086 hasConcept C1491633281 @default.
• W2163070086 hasConcept C153911025 @default.
• W2163070086 hasConcept C16224149 @default.
• W2163070086 hasConcept C167454224 @default.
• W2163070086 hasConcept C170493617 @default.
• W2163070086 hasConcept C185946421 @default.
• W2163070086 hasConcept C195687474 @default.
• W2163070086 hasConcept C203014093 @default.
• W2163070086 hasConcept C2776985958 @default.
• W2163070086 hasConcept C2777761686 @default.
• W2163070086 hasConcept C2779835222 @default.
• W2163070086 hasConcept C2780385752 @default.
• W2163070086 hasConcept C4175445 @default.
• W2163070086 hasConcept C55493867 @default.
• W2163070086 hasConcept C85789140 @default.
• W2163070086 hasConcept C86803240 @default.
• W2163070086 hasConceptScore W2163070086C1491633281 @default.
• W2163070086 hasConceptScore W2163070086C153911025 @default.
• W2163070086 hasConceptScore W2163070086C16224149 @default.
• W2163070086 hasConceptScore W2163070086C167454224 @default.
• W2163070086 hasConceptScore W2163070086C170493617 @default.
• W2163070086 hasConceptScore W2163070086C185946421 @default.
• W2163070086 hasConceptScore W2163070086C195687474 @default.
• W2163070086 hasConceptScore W2163070086C203014093 @default.
• W2163070086 hasConceptScore W2163070086C2776985958 @default.
• W2163070086 hasConceptScore W2163070086C2777761686 @default.
• W2163070086 hasConceptScore W2163070086C2779835222 @default.
• W2163070086 hasConceptScore W2163070086C2780385752 @default.
• W2163070086 hasConceptScore W2163070086C4175445 @default.
• W2163070086 hasConceptScore W2163070086C55493867 @default.
• W2163070086 hasConceptScore W2163070086C85789140 @default.

• next