FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2163669192> ?p ?o ?g. }

• W2163669192 endingPage "520" @default.
• W2163669192 startingPage "513" @default.
• W2163669192 abstract "Quantitative proteomic studies using cleavable isotope-coded affinity tags (cICAT) in concert with tandem mass spectrometry (MS/MS) permit unbiased comparisons between biologically distinct samples. We sought to determine the analytical characteristics of cICAT-based studies by examining the cumulative results of multiple, separate cICAT-based experiments involving human lymphoma-derived cells. We found that the number of identified proteins increased with larger numbers of fractions analyzed. The majority of proteins were identified by single peptides. Only 24 to 41% of the peptides contained cysteine residues, but 85% of the cysteine-containing peptides yielded quantification data. Approximately 28% of all identified proteins yielded quantification data, with 57% of these being differentially expressed by at least 1.5-fold. The quantification ratios of peptides for proteins with multiple quantified peptides were concordant in trend in 87% of instances. cICAT-labeled peptides identified proteins in all subcellular compartments without significant bias. Analysis of the flow-through fraction did not increase the number of peptides identified per protein. Our studies indicate that cICAT-LC-MS/MS yields quantifications primarily based on single peptides, and analysis of flow-through peptides does not contribute signifi-cantly to the results. Nevertheless, identifications based on single cICAT-labeled peptides with tryptic ends provide sufficiently reliable protein identifications and quantification information in cICAT-LC-MS/MS-based proteomic studies." @default.
• W2163669192 created "2016-06-24" @default.
• W2163669192 creator A5008239063 @default.
• W2163669192 creator A5019959500 @default.
• W2163669192 creator A5041898934 @default.
• W2163669192 creator A5056007865 @default.
• W2163669192 date "2006-09-01" @default.
• W2163669192 modified "2023-10-10" @default.
• W2163669192 title "Analytical Characteristics of Cleavable Isotope-Coded Affinity Tag-LC-Tandem Mass Spectrometry for Quantitative Proteomic Studies" @default.
• W2163669192 cites W1797925867 @default.
• W2163669192 cites W1969416735 @default.
• W2163669192 cites W2015556811 @default.
• W2163669192 cites W2038749208 @default.
• W2163669192 cites W2048333869 @default.
• W2163669192 cites W2101128616 @default.
• W2163669192 cites W2107323383 @default.
• W2163669192 cites W2109691687 @default.
• W2163669192 cites W2110603815 @default.
• W2163669192 cites W2111208057 @default.
• W2163669192 cites W2112078820 @default.
• W2163669192 cites W2112496677 @default.
• W2163669192 cites W2139703939 @default.
• W2163669192 cites W2140946052 @default.
• W2163669192 cites W2148810272 @default.
• W2163669192 cites W2153132589 @default.
• W2163669192 cites W2162311651 @default.
• W2163669192 doi "https://doi.org/10.2353/jmoldx.2006.060036" @default.
• W2163669192 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1867626" @default.
• W2163669192 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16931593" @default.
• W2163669192 hasPublicationYear "2006" @default.
• W2163669192 type Work @default.
• W2163669192 sameAs 2163669192 @default.
• W2163669192 citedByCount "20" @default.
• W2163669192 countsByYear W21636691922012 @default.
• W2163669192 countsByYear W21636691922013 @default.
• W2163669192 countsByYear W21636691922015 @default.
• W2163669192 countsByYear W21636691922019 @default.
• W2163669192 crossrefType "journal-article" @default.
• W2163669192 hasAuthorship W2163669192A5008239063 @default.
• W2163669192 hasAuthorship W2163669192A5019959500 @default.
• W2163669192 hasAuthorship W2163669192A5041898934 @default.
• W2163669192 hasAuthorship W2163669192A5056007865 @default.
• W2163669192 hasBestOaLocation W21636691921 @default.
• W2163669192 hasConcept C104317684 @default.
• W2163669192 hasConcept C162356407 @default.
• W2163669192 hasConcept C181199279 @default.
• W2163669192 hasConcept C184185385 @default.
• W2163669192 hasConcept C185592680 @default.
• W2163669192 hasConcept C202157981 @default.
• W2163669192 hasConcept C2779201268 @default.
• W2163669192 hasConcept C2779281246 @default.
• W2163669192 hasConcept C31827203 @default.
• W2163669192 hasConcept C34905852 @default.
• W2163669192 hasConcept C43617362 @default.
• W2163669192 hasConcept C46111723 @default.
• W2163669192 hasConcept C55493867 @default.
• W2163669192 hasConcept C70721500 @default.
• W2163669192 hasConcept C73090800 @default.
• W2163669192 hasConcept C80311884 @default.
• W2163669192 hasConcept C86153913 @default.
• W2163669192 hasConcept C86803240 @default.
• W2163669192 hasConceptScore W2163669192C104317684 @default.
• W2163669192 hasConceptScore W2163669192C162356407 @default.
• W2163669192 hasConceptScore W2163669192C181199279 @default.
• W2163669192 hasConceptScore W2163669192C184185385 @default.
• W2163669192 hasConceptScore W2163669192C185592680 @default.
• W2163669192 hasConceptScore W2163669192C202157981 @default.
• W2163669192 hasConceptScore W2163669192C2779201268 @default.
• W2163669192 hasConceptScore W2163669192C2779281246 @default.
• W2163669192 hasConceptScore W2163669192C31827203 @default.
• W2163669192 hasConceptScore W2163669192C34905852 @default.
• W2163669192 hasConceptScore W2163669192C43617362 @default.
• W2163669192 hasConceptScore W2163669192C46111723 @default.
• W2163669192 hasConceptScore W2163669192C55493867 @default.
• W2163669192 hasConceptScore W2163669192C70721500 @default.
• W2163669192 hasConceptScore W2163669192C73090800 @default.
• W2163669192 hasConceptScore W2163669192C80311884 @default.
• W2163669192 hasConceptScore W2163669192C86153913 @default.
• W2163669192 hasConceptScore W2163669192C86803240 @default.
• W2163669192 hasIssue "4" @default.
• W2163669192 hasLocation W21636691921 @default.
• W2163669192 hasLocation W21636691922 @default.
• W2163669192 hasLocation W21636691923 @default.
• W2163669192 hasLocation W21636691924 @default.
• W2163669192 hasOpenAccess W2163669192 @default.
• W2163669192 hasPrimaryLocation W21636691921 @default.
• W2163669192 hasRelatedWork W2121202956 @default.
• W2163669192 hasRelatedWork W2326729924 @default.
• W2163669192 hasRelatedWork W2465149832 @default.
• W2163669192 hasRelatedWork W2480853431 @default.
• W2163669192 hasRelatedWork W2792087494 @default.
• W2163669192 hasRelatedWork W2944683884 @default.
• W2163669192 hasRelatedWork W2971374468 @default.
• W2163669192 hasRelatedWork W3197236421 @default.
• W2163669192 hasRelatedWork W4302774012 @default.
• W2163669192 hasRelatedWork W4307747561 @default.
• W2163669192 hasVolume "8" @default.
• W2163669192 isParatext "false" @default.

• next