FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2175181431> ?p ?o ?g. }

• W2175181431 endingPage "62" @default.
• W2175181431 startingPage "62" @default.
• W2175181431 abstract "The procalcitonin (PCT) assay is an accurate screening test for identifying invasive bacterial infection (IBI); however, data on the PCT assay in very young infants are insufficient.To assess the diagnostic characteristics of the PCT assay for detecting serious bacterial infection (SBI) and IBI in febrile infants aged 7 to 91 days.A prospective cohort study that included infants aged 7 to 91 days admitted for fever to 15 French pediatric emergency departments was conducted for a period of 30 months (October 1, 2008, through March 31, 2011). The data management and analysis were performed from October 1, 2011, through October 31, 2014.The diagnostic characteristics of the PCT assay, C-reactive protein (CRP) concentration, white blood cell (WBC) count, and absolute neutrophil cell (ANC) count for detecting SBI and IBI were described and compared for the overall population and subgroups of infants according to the age and the duration of fever. Laboratory test cutoff values were calculated based on receiver operating characteristic (ROC) curve analysis. The SBIs were defined as a pathogenic bacteria in positive culture of blood, cerebrospinal fluid, urine, or stool samples, including bacteremia and bacterial meningitis classified as IBIs.Among the 2047 infants included, 139 (6.8%) were diagnosed as having an SBI and 21 (1.0%) as having an IBI (11.0% and 1.7% of those with blood culture (n = 1258), respectively). The PCT assay offered an area under the curve (AUC) of ROC curve similar to that for CRP concentration for the detection of SBI (AUC, 0.81; 95% CI, 0.75-0.86; vs AUC, 0.80; 95% CI, 0.75-0.85; P = .70). The AUC ROC curve for the detection of IBI for the PCT assay was significantly higher than that for the CRP concentration (AUC, 0.91; 95% CI, 0.83-0.99; vs AUC, 0.77; 95% CI, 0.65-0.89; P = .002). Using a cutoff value of 0.3 ng/mL for PCT and 20 mg/L for CRP, negative likelihood ratios were 0.3 (95% CI, 0.2-0.5) for identifying SBI and 0.1 (95% CI, 0.03-0.4) and 0.3 (95% CI, 0.2-0.7) for identifying IBI, respectively. Similar results were obtained for the subgroup of infants younger than 1 month and for those with fever lasting less than 6 hours.The PCT assay has better diagnostic accuracy than CRP measurement for detecting IBI; the 2 tests perform similarly for identifying SBI in febrile infants aged 7 to 91 days." @default.
• W2175181431 created "2016-06-24" @default.
• W2175181431 creator A5000119241 @default.
• W2175181431 creator A5007508311 @default.
• W2175181431 creator A5009172554 @default.
• W2175181431 creator A5011936234 @default.
• W2175181431 creator A5012974700 @default.
• W2175181431 creator A5015394441 @default.
• W2175181431 creator A5021540068 @default.
• W2175181431 creator A5023447619 @default.
• W2175181431 creator A5032610879 @default.
• W2175181431 creator A5037350839 @default.
• W2175181431 creator A5049143196 @default.
• W2175181431 creator A5060300841 @default.
• W2175181431 creator A5063808596 @default.
• W2175181431 creator A5064376700 @default.
• W2175181431 creator A5068440134 @default.
• W2175181431 creator A5070926957 @default.
• W2175181431 creator A5079379001 @default.
• W2175181431 creator A5081918755 @default.
• W2175181431 creator A5082568357 @default.
• W2175181431 date "2016-01-01" @default.
• W2175181431 modified "2023-10-17" @default.
• W2175181431 title "Use of Procalcitonin Assays to Predict Serious Bacterial Infection in Young Febrile Infants" @default.
• W2175181431 cites W1511532888 @default.
• W2175181431 cites W1653432824 @default.
• W2175181431 cites W1965018702 @default.
• W2175181431 cites W1967574437 @default.
• W2175181431 cites W1968465987 @default.
• W2175181431 cites W1970294295 @default.
• W2175181431 cites W1979915236 @default.
• W2175181431 cites W1986921709 @default.
• W2175181431 cites W1992612216 @default.
• W2175181431 cites W2016923649 @default.
• W2175181431 cites W2021629682 @default.
• W2175181431 cites W2021756164 @default.
• W2175181431 cites W2025850747 @default.
• W2175181431 cites W2026904805 @default.
• W2175181431 cites W2053946384 @default.
• W2175181431 cites W2059789902 @default.
• W2175181431 cites W2064293690 @default.
• W2175181431 cites W2067017082 @default.
• W2175181431 cites W2068808247 @default.
• W2175181431 cites W2073778897 @default.
• W2175181431 cites W2082406535 @default.
• W2175181431 cites W2094439714 @default.
• W2175181431 cites W2095918352 @default.
• W2175181431 cites W2099894685 @default.
• W2175181431 cites W2103567209 @default.
• W2175181431 cites W2113252049 @default.
• W2175181431 cites W2115279909 @default.
• W2175181431 cites W2120274587 @default.
• W2175181431 cites W2120520430 @default.
• W2175181431 cites W2121836919 @default.
• W2175181431 cites W2123037629 @default.
• W2175181431 cites W2124499584 @default.
• W2175181431 cites W2124750719 @default.
• W2175181431 cites W2138904389 @default.
• W2175181431 cites W2148461522 @default.
• W2175181431 cites W2151474641 @default.
• W2175181431 cites W2157825442 @default.
• W2175181431 cites W2159219977 @default.
• W2175181431 cites W2166256538 @default.
• W2175181431 cites W2328176404 @default.
• W2175181431 cites W2760579413 @default.
• W2175181431 doi "https://doi.org/10.1001/jamapediatrics.2015.3210" @default.
• W2175181431 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27088558" @default.
• W2175181431 hasPublicationYear "2016" @default.
• W2175181431 type Work @default.
• W2175181431 sameAs 2175181431 @default.
• W2175181431 citedByCount "154" @default.
• W2175181431 countsByYear W21751814312016 @default.
• W2175181431 countsByYear W21751814312017 @default.
• W2175181431 countsByYear W21751814312018 @default.
• W2175181431 countsByYear W21751814312019 @default.
• W2175181431 countsByYear W21751814312020 @default.
• W2175181431 countsByYear W21751814312021 @default.
• W2175181431 countsByYear W21751814312022 @default.
• W2175181431 countsByYear W21751814312023 @default.
• W2175181431 crossrefType "journal-article" @default.
• W2175181431 hasAuthorship W2175181431A5000119241 @default.
• W2175181431 hasAuthorship W2175181431A5007508311 @default.
• W2175181431 hasAuthorship W2175181431A5009172554 @default.
• W2175181431 hasAuthorship W2175181431A5011936234 @default.
• W2175181431 hasAuthorship W2175181431A5012974700 @default.
• W2175181431 hasAuthorship W2175181431A5015394441 @default.
• W2175181431 hasAuthorship W2175181431A5021540068 @default.
• W2175181431 hasAuthorship W2175181431A5023447619 @default.
• W2175181431 hasAuthorship W2175181431A5032610879 @default.
• W2175181431 hasAuthorship W2175181431A5037350839 @default.
• W2175181431 hasAuthorship W2175181431A5049143196 @default.
• W2175181431 hasAuthorship W2175181431A5060300841 @default.
• W2175181431 hasAuthorship W2175181431A5063808596 @default.
• W2175181431 hasAuthorship W2175181431A5064376700 @default.
• W2175181431 hasAuthorship W2175181431A5068440134 @default.
• W2175181431 hasAuthorship W2175181431A5070926957 @default.
• W2175181431 hasAuthorship W2175181431A5079379001 @default.
• W2175181431 hasAuthorship W2175181431A5081918755 @default.

• next