FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2183670502> ?p ?o ?g. }

• W2183670502 endingPage "1644" @default.
• W2183670502 startingPage "1637" @default.
• W2183670502 abstract "In England, antenatal pertussis immunization using a tetanus/low-dose diphtheria/5-component acellular-pertussis/inactivated-polio (TdaP5/IPV) vaccine was introduced in October 2012. We assessed infant responses to antigens in the maternal vaccine and to those conjugated to tetanus (TT) or the diphtheria toxin variant, CRM.Infants of 141 TdaP5/IPV-vaccinated mothers in Southern England immunized with DTaP5/IPV/Haemophilus influenzae b (Hib-TT) vaccine at 2-3-4 months, 13-valent pneumococcal vaccine (PCV13, CRM-conjugated) at 2-4 months and 1 or 2 meningococcal C vaccine (MCC-CRM- or MCC-TT) doses at 3-4 months had blood samples taken at 2 and/or 5 months of age.Antibody responses to pertussis toxin (PT), filamentous hemagglutinin (FHA), fimbriae 2 + 3 (FIMs), diphtheria, tetanus, Hib, MCC and PCV13 serotypes were compared to responses in a historical cohort of 246 infants born to mothers not vaccinated in pregnancy. Infants had high pertussis antibody concentrations pre-immunization but only PT antibodies increased post-immunization (fold-change, 2.64; 95% confidence interval [CI], 2.12-3.30; P < .001), whereas FHA antibodies fell (fold-change, 0.56; 95% CI, .48-.65; P < .001). Compared with infants of unvaccinated mothers, PT, FHA, and FIMs antibodies were lower post-vaccination, with fold-differences of 0.67 (0.58-0.77; P < .001), 0.62 (0.54-0.71; P < .001) and 0.51 (0.42-0.62; P < .001), respectively. Antibodies to diphtheria and some CRM-conjugated antigens were also lower, although most infants achieved protective thresholds; antibodies to tetanus and Hib were higher.Antenatal pertussis immunization results in high infant pre-immunization antibody concentrations, but blunts subsequent responses to pertussis vaccine and some CRM-conjugated antigens. In countries with no pertussis booster until school age, continued monitoring of protection against pertussis is essential." @default.
• W2183670502 created "2016-06-24" @default.
• W2183670502 creator A5001471272 @default.
• W2183670502 creator A5008173791 @default.
• W2183670502 creator A5015087698 @default.
• W2183670502 creator A5016489221 @default.
• W2183670502 creator A5046888535 @default.
• W2183670502 creator A5047481687 @default.
• W2183670502 creator A5050450991 @default.
• W2183670502 creator A5053121427 @default.
• W2183670502 creator A5054039682 @default.
• W2183670502 creator A5064962511 @default.
• W2183670502 creator A5066158785 @default.
• W2183670502 creator A5072180185 @default.
• W2183670502 creator A5072485453 @default.
• W2183670502 creator A5075282768 @default.
• W2183670502 creator A5079855257 @default.
• W2183670502 creator A5081962661 @default.
• W2183670502 creator A5088935966 @default.
• W2183670502 date "2015-09-15" @default.
• W2183670502 modified "2023-10-17" @default.
• W2183670502 title "Antibody Responses After Primary Immunization in Infants Born to Women Receiving a Pertussis-containing Vaccine During Pregnancy: Single Arm Observational Study With a Historical Comparator" @default.
• W2183670502 cites W1912692997 @default.
• W2183670502 cites W1983797500 @default.
• W2183670502 cites W2000709287 @default.
• W2183670502 cites W2018059775 @default.
• W2183670502 cites W2044300321 @default.
• W2183670502 cites W2045406056 @default.
• W2183670502 cites W2050308265 @default.
• W2183670502 cites W2050473765 @default.
• W2183670502 cites W2084460535 @default.
• W2183670502 cites W2089266980 @default.
• W2183670502 cites W2102788190 @default.
• W2183670502 cites W2110580732 @default.
• W2183670502 cites W2121403515 @default.
• W2183670502 cites W2123619196 @default.
• W2183670502 cites W2160358721 @default.
• W2183670502 cites W2164938850 @default.
• W2183670502 cites W2319271764 @default.
• W2183670502 doi "https://doi.org/10.1093/cid/civ695" @default.
• W2183670502 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26374816" @default.
• W2183670502 hasPublicationYear "2015" @default.
• W2183670502 type Work @default.
• W2183670502 sameAs 2183670502 @default.
• W2183670502 citedByCount "148" @default.
• W2183670502 countsByYear W21836705022015 @default.
• W2183670502 countsByYear W21836705022016 @default.
• W2183670502 countsByYear W21836705022017 @default.
• W2183670502 countsByYear W21836705022018 @default.
• W2183670502 countsByYear W21836705022019 @default.
• W2183670502 countsByYear W21836705022020 @default.
• W2183670502 countsByYear W21836705022021 @default.
• W2183670502 countsByYear W21836705022022 @default.
• W2183670502 countsByYear W21836705022023 @default.
• W2183670502 crossrefType "journal-article" @default.
• W2183670502 hasAuthorship W2183670502A5001471272 @default.
• W2183670502 hasAuthorship W2183670502A5008173791 @default.
• W2183670502 hasAuthorship W2183670502A5015087698 @default.
• W2183670502 hasAuthorship W2183670502A5016489221 @default.
• W2183670502 hasAuthorship W2183670502A5046888535 @default.
• W2183670502 hasAuthorship W2183670502A5047481687 @default.
• W2183670502 hasAuthorship W2183670502A5050450991 @default.
• W2183670502 hasAuthorship W2183670502A5053121427 @default.
• W2183670502 hasAuthorship W2183670502A5054039682 @default.
• W2183670502 hasAuthorship W2183670502A5064962511 @default.
• W2183670502 hasAuthorship W2183670502A5066158785 @default.
• W2183670502 hasAuthorship W2183670502A5072180185 @default.
• W2183670502 hasAuthorship W2183670502A5072485453 @default.
• W2183670502 hasAuthorship W2183670502A5075282768 @default.
• W2183670502 hasAuthorship W2183670502A5079855257 @default.
• W2183670502 hasAuthorship W2183670502A5081962661 @default.
• W2183670502 hasAuthorship W2183670502A5088935966 @default.
• W2183670502 hasBestOaLocation W21836705021 @default.
• W2183670502 hasConcept C126322002 @default.
• W2183670502 hasConcept C159654299 @default.
• W2183670502 hasConcept C170493617 @default.
• W2183670502 hasConcept C187212893 @default.
• W2183670502 hasConcept C203014093 @default.
• W2183670502 hasConcept C22070199 @default.
• W2183670502 hasConcept C2779214499 @default.
• W2183670502 hasConcept C2779634000 @default.
• W2183670502 hasConcept C2779841045 @default.
• W2183670502 hasConcept C2780572238 @default.
• W2183670502 hasConcept C2780801004 @default.
• W2183670502 hasConcept C49773422 @default.
• W2183670502 hasConcept C71924100 @default.
• W2183670502 hasConcept C80631254 @default.
• W2183670502 hasConcept C8439097 @default.
• W2183670502 hasConceptScore W2183670502C126322002 @default.
• W2183670502 hasConceptScore W2183670502C159654299 @default.
• W2183670502 hasConceptScore W2183670502C170493617 @default.
• W2183670502 hasConceptScore W2183670502C187212893 @default.
• W2183670502 hasConceptScore W2183670502C203014093 @default.
• W2183670502 hasConceptScore W2183670502C22070199 @default.
• W2183670502 hasConceptScore W2183670502C2779214499 @default.
• W2183670502 hasConceptScore W2183670502C2779634000 @default.
• W2183670502 hasConceptScore W2183670502C2779841045 @default.
• W2183670502 hasConceptScore W2183670502C2780572238 @default.

• next