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• W2267751543 endingPage "72" @default.
• W2267751543 startingPage "49" @default.
• W2267751543 abstract "This chapter discusses some of the physical and chemical properties of mucus that help protect epithelial surfaces. Mucus secretions sustain complex, thriving, and local ecosystems. Mucus gels, formed by secreted mucins, are loaded with cells, bacteria, nutrients, protective factors, and wastes. Many of the constituents—including the secreted mucins—are specific to the particular mucosal surface. Most epithelial surfaces are covered by a continuous blanket of mucus despite the vigorous stirring actions of blinking eyelids, coughing, chewing, and swallowing. The shear dependent viscosity of mucus helps maintain an unstirred layer of gel through which particles must diffuse before they can contact epithelial cells. Even the mucus that wraps particles of chyme forms an unstirred layer around the particle. These unstirred layers of mucus form a diffusional barrier that helps create much of the selective permeability of the mucus blanket. To function well—the thickness of the unstirred layer, like the viscoelasticity of mucus—must be regulated to achieve a balance." @default.
• W2267751543 created "2016-06-24" @default.
• W2267751543 creator A5023574039 @default.
• W2267751543 date "2005-01-01" @default.
• W2267751543 modified "2023-09-25" @default.
• W2267751543 title "Mucus" @default.
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