Matches in SemOpenAlex for { <https://semopenalex.org/work/W2291170421> ?p ?o ?g. }
- W2291170421 endingPage "2846" @default.
- W2291170421 startingPage "2841" @default.
- W2291170421 abstract "The free fatty acid receptor 1 (FFA1 or GPR40) is established as an interesting potential target for treatment of type 2 diabetes. However, to obtain optimal ligands, it may be necessary to limit both lipophilicity and polar surface area, translating to a need for small compounds. We here describe the identification of 24, a potent FFA1 agonist with low lipophilicity and very high ligand efficiency that exhibit robust glucose lowering effect." @default.
- W2291170421 created "2016-06-24" @default.
- W2291170421 creator A5012916428 @default.
- W2291170421 creator A5023044490 @default.
- W2291170421 creator A5032193828 @default.
- W2291170421 creator A5034072900 @default.
- W2291170421 creator A5038614242 @default.
- W2291170421 creator A5040763004 @default.
- W2291170421 creator A5041231391 @default.
- W2291170421 creator A5051585961 @default.
- W2291170421 creator A5053164619 @default.
- W2291170421 creator A5064230603 @default.
- W2291170421 creator A5064573477 @default.
- W2291170421 creator A5074853390 @default.
- W2291170421 creator A5075411882 @default.
- W2291170421 creator A5084454705 @default.
- W2291170421 date "2016-03-15" @default.
- W2291170421 modified "2023-10-04" @default.
- W2291170421 title "Discovery of a Potent Free Fatty Acid 1 Receptor Agonist with Low Lipophilicity, Low Polar Surface Area, and Robust in Vivo Efficacy" @default.
- W2291170421 cites W1555310957 @default.
- W2291170421 cites W1663154925 @default.
- W2291170421 cites W1956939595 @default.
- W2291170421 cites W1974405795 @default.
- W2291170421 cites W1974530518 @default.
- W2291170421 cites W1979161189 @default.
- W2291170421 cites W1995613581 @default.
- W2291170421 cites W2006474213 @default.
- W2291170421 cites W2008525757 @default.
- W2291170421 cites W2021057017 @default.
- W2291170421 cites W2048742322 @default.
- W2291170421 cites W2051707977 @default.
- W2291170421 cites W2059351011 @default.
- W2291170421 cites W2061422418 @default.
- W2291170421 cites W2061650356 @default.
- W2291170421 cites W2062458432 @default.
- W2291170421 cites W2073474683 @default.
- W2291170421 cites W2074409801 @default.
- W2291170421 cites W2075615929 @default.
- W2291170421 cites W2084862721 @default.
- W2291170421 cites W2086406724 @default.
- W2291170421 cites W2089328778 @default.
- W2291170421 cites W2097559461 @default.
- W2291170421 cites W2102964449 @default.
- W2291170421 cites W2127867476 @default.
- W2291170421 cites W2128326754 @default.
- W2291170421 cites W2130404519 @default.
- W2291170421 cites W2132566819 @default.
- W2291170421 cites W2141528038 @default.
- W2291170421 cites W2148829653 @default.
- W2291170421 cites W2156398717 @default.
- W2291170421 cites W2163448046 @default.
- W2291170421 cites W2326172157 @default.
- W2291170421 cites W2326770901 @default.
- W2291170421 cites W4248107770 @default.
- W2291170421 doi "https://doi.org/10.1021/acs.jmedchem.5b01962" @default.
- W2291170421 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26928019" @default.
- W2291170421 hasPublicationYear "2016" @default.
- W2291170421 type Work @default.
- W2291170421 sameAs 2291170421 @default.
- W2291170421 citedByCount "20" @default.
- W2291170421 countsByYear W22911704212016 @default.
- W2291170421 countsByYear W22911704212017 @default.
- W2291170421 countsByYear W22911704212018 @default.
- W2291170421 countsByYear W22911704212019 @default.
- W2291170421 countsByYear W22911704212020 @default.
- W2291170421 countsByYear W22911704212021 @default.
- W2291170421 countsByYear W22911704212022 @default.
- W2291170421 countsByYear W22911704212023 @default.
- W2291170421 crossrefType "journal-article" @default.
- W2291170421 hasAuthorship W2291170421A5012916428 @default.
- W2291170421 hasAuthorship W2291170421A5023044490 @default.
- W2291170421 hasAuthorship W2291170421A5032193828 @default.
- W2291170421 hasAuthorship W2291170421A5034072900 @default.
- W2291170421 hasAuthorship W2291170421A5038614242 @default.
- W2291170421 hasAuthorship W2291170421A5040763004 @default.
- W2291170421 hasAuthorship W2291170421A5041231391 @default.
- W2291170421 hasAuthorship W2291170421A5051585961 @default.
- W2291170421 hasAuthorship W2291170421A5053164619 @default.
- W2291170421 hasAuthorship W2291170421A5064230603 @default.
- W2291170421 hasAuthorship W2291170421A5064573477 @default.
- W2291170421 hasAuthorship W2291170421A5074853390 @default.
- W2291170421 hasAuthorship W2291170421A5075411882 @default.
- W2291170421 hasAuthorship W2291170421A5084454705 @default.
- W2291170421 hasConcept C116569031 @default.
- W2291170421 hasConcept C121332964 @default.
- W2291170421 hasConcept C1276947 @default.
- W2291170421 hasConcept C150903083 @default.
- W2291170421 hasConcept C170493617 @default.
- W2291170421 hasConcept C178790620 @default.
- W2291170421 hasConcept C185592680 @default.
- W2291170421 hasConcept C201399114 @default.
- W2291170421 hasConcept C202751555 @default.
- W2291170421 hasConcept C204171352 @default.
- W2291170421 hasConcept C207001950 @default.
- W2291170421 hasConcept C207464780 @default.
- W2291170421 hasConcept C21951064 @default.
- W2291170421 hasConcept C2777752112 @default.
- W2291170421 hasConcept C2778938600 @default.