Matches in SemOpenAlex for { <https://semopenalex.org/work/W2293462703> ?p ?o ?g. }
- W2293462703 endingPage "690" @default.
- W2293462703 startingPage "682" @default.
- W2293462703 abstract "We present the systematic design, fabrication, and characterization of a multiplexed label-free lab-on-a-chip biosensor using silicon nitride (SiN) microring resonators. Sensor design is addressed through a systematic approach that enables optimizing the sensor according to the specific noise characteristics of the setup. We find that an optimal 6 dB undercoupled resonator consumes 40% less power in our platform to achieve the same limit-of-detection as the conventional designs using critically coupled resonators that have the maximum light-matter interaction. We lay out an optimization framework that enables the generalization of our method for any type of optical resonator and noise characteristics. The device is fabricated using a CMOS-compatible process, and an efficient swabbing lift-off technique is introduced for the deposition of the protective oxide layer. This technique increases the lift-off quality and yield compared to common lift-off methods based on agitation. The complete sensor system, including microfluidic flow cell and surface functionalization with glycan receptors, is tested for the multiplexed detection of Aleuria Aurantia Lectin (AAL) and Sambucus Nigra Lectin (SNA). Further analysis shows that the sensor limit of detection is 2 × 10(-6) RIU for bulk refractive index, 1 pg/mm(2) for surface-adsorbed mass, and ∼ 10 pM for the glycan/lectins studied here." @default.
- W2293462703 created "2016-06-24" @default.
- W2293462703 creator A5011072613 @default.
- W2293462703 creator A5012593770 @default.
- W2293462703 creator A5014221001 @default.
- W2293462703 creator A5023341393 @default.
- W2293462703 creator A5024615055 @default.
- W2293462703 creator A5025615356 @default.
- W2293462703 creator A5030305532 @default.
- W2293462703 creator A5038994472 @default.
- W2293462703 creator A5055383144 @default.
- W2293462703 date "2016-06-01" @default.
- W2293462703 modified "2023-09-27" @default.
- W2293462703 title "Multiplexed detection of lectins using integrated glycan-coated microring resonators" @default.
- W2293462703 cites W1529058610 @default.
- W2293462703 cites W1967596920 @default.
- W2293462703 cites W1977752202 @default.
- W2293462703 cites W2001031715 @default.
- W2293462703 cites W2008252836 @default.
- W2293462703 cites W2012496731 @default.
- W2293462703 cites W2016022388 @default.
- W2293462703 cites W2018097263 @default.
- W2293462703 cites W2027077554 @default.
- W2293462703 cites W2027675046 @default.
- W2293462703 cites W2028671326 @default.
- W2293462703 cites W2031599845 @default.
- W2293462703 cites W2033585088 @default.
- W2293462703 cites W2034076799 @default.
- W2293462703 cites W2035306395 @default.
- W2293462703 cites W2035332451 @default.
- W2293462703 cites W2056127911 @default.
- W2293462703 cites W2057517370 @default.
- W2293462703 cites W2059255935 @default.
- W2293462703 cites W2060312517 @default.
- W2293462703 cites W2079602279 @default.
- W2293462703 cites W2081695565 @default.
- W2293462703 cites W2083556833 @default.
- W2293462703 cites W2103739638 @default.
- W2293462703 cites W2114578038 @default.
- W2293462703 cites W2116416536 @default.
- W2293462703 cites W2117571129 @default.
- W2293462703 cites W2155189614 @default.
- W2293462703 cites W2155266621 @default.
- W2293462703 cites W2157214340 @default.
- W2293462703 cites W2164697448 @default.
- W2293462703 cites W2171459724 @default.
- W2293462703 cites W4230575387 @default.
- W2293462703 doi "https://doi.org/10.1016/j.bios.2016.01.051" @default.
- W2293462703 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26826877" @default.
- W2293462703 hasPublicationYear "2016" @default.
- W2293462703 type Work @default.
- W2293462703 sameAs 2293462703 @default.
- W2293462703 citedByCount "19" @default.
- W2293462703 countsByYear W22934627032016 @default.
- W2293462703 countsByYear W22934627032018 @default.
- W2293462703 countsByYear W22934627032019 @default.
- W2293462703 countsByYear W22934627032020 @default.
- W2293462703 countsByYear W22934627032021 @default.
- W2293462703 countsByYear W22934627032022 @default.
- W2293462703 crossrefType "journal-article" @default.
- W2293462703 hasAuthorship W2293462703A5011072613 @default.
- W2293462703 hasAuthorship W2293462703A5012593770 @default.
- W2293462703 hasAuthorship W2293462703A5014221001 @default.
- W2293462703 hasAuthorship W2293462703A5023341393 @default.
- W2293462703 hasAuthorship W2293462703A5024615055 @default.
- W2293462703 hasAuthorship W2293462703A5025615356 @default.
- W2293462703 hasAuthorship W2293462703A5030305532 @default.
- W2293462703 hasAuthorship W2293462703A5038994472 @default.
- W2293462703 hasAuthorship W2293462703A5055383144 @default.
- W2293462703 hasBestOaLocation W22934627031 @default.
- W2293462703 hasConcept C115537861 @default.
- W2293462703 hasConcept C119128265 @default.
- W2293462703 hasConcept C136525101 @default.
- W2293462703 hasConcept C142724271 @default.
- W2293462703 hasConcept C147789679 @default.
- W2293462703 hasConcept C160756335 @default.
- W2293462703 hasConcept C171250308 @default.
- W2293462703 hasConcept C185592680 @default.
- W2293462703 hasConcept C192562407 @default.
- W2293462703 hasConcept C204787440 @default.
- W2293462703 hasConcept C43617362 @default.
- W2293462703 hasConcept C49040817 @default.
- W2293462703 hasConcept C71924100 @default.
- W2293462703 hasConcept C8673954 @default.
- W2293462703 hasConcept C97126364 @default.
- W2293462703 hasConceptScore W2293462703C115537861 @default.
- W2293462703 hasConceptScore W2293462703C119128265 @default.
- W2293462703 hasConceptScore W2293462703C136525101 @default.
- W2293462703 hasConceptScore W2293462703C142724271 @default.
- W2293462703 hasConceptScore W2293462703C147789679 @default.
- W2293462703 hasConceptScore W2293462703C160756335 @default.
- W2293462703 hasConceptScore W2293462703C171250308 @default.
- W2293462703 hasConceptScore W2293462703C185592680 @default.
- W2293462703 hasConceptScore W2293462703C192562407 @default.
- W2293462703 hasConceptScore W2293462703C204787440 @default.
- W2293462703 hasConceptScore W2293462703C43617362 @default.
- W2293462703 hasConceptScore W2293462703C49040817 @default.
- W2293462703 hasConceptScore W2293462703C71924100 @default.