FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2330241036> ?p ?o ?g. }

• W2330241036 endingPage "73" @default.
• W2330241036 startingPage "56" @default.
• W2330241036 abstract "It is now well established by many groups that surgery on the aortic arch may be achieved with consistently low morbidity and mortality along with relatively good survival compared to estimated natural history for a number of aortic arch pathologies. The objectives of this study were to: 1) report, compare, and analyze our morbidity and mortality outcomes for hemiarch and total aortic arch surgery; 2) examine the survival benefit of hemiarch and total aortic arch surgery compared to age- and sex-matched controls; and 3) define factors which influence survival in these two groups and, in particular, identify those that are modifiable and potentially actionable.Outcomes from patients undergoing surgical resection of both hemiarch and total aortic arch at the Liverpool Heart and Chest Hospital between June 1999 and December 2012 were examined in a retrospective analysis of data collected for The Society for Cardiothoracic Surgeons (UK).Over the period studied, a total of 1240 patients underwent aortic surgery, from which 287 were identified as having undergone hemi to total aortic arch surgery under deep or moderate hypothermic circulatory arrest. Twenty three percent of patients' surgeries were nonelective. The median age at the time of patients undergoing elective hemiarch was 64.3 years and total arch was 65.3 years (P = 0.25), with 40.1% being female in the entire group. A total of 140 patients underwent elective hemiarch replacement, while 81 underwent elective total arch replacement. Etiology of the aortic pathology was degenerative in 51.2% of the two groups, with 87.1% requiring aortic valve repair in the elective hemiarch group and 64.2% in the elective total arch group (P < 0.001). Elective in-hospital mortality was 2.1% in the hemiarch group and 6.2% (P = 0.15) in the total arch group with corresponding rates of stroke (2.9% versus 4.9%, P = 0.47), renal failure (4.3% versus 6.2%, P = 0.54), reexploration for bleeding (4.3% versus 4.9%, P > 0.99), and prolonged ventilation (8.6% versus 16.1%, P = 0.09). Overall mortality was 20.9% at 5 years, while it was 15.7% in the elective hemiarch and 25.9% in the total arch group (P = 0.065). Process control charts demonstrated stability of annualized mortality outcomes over the study period. Survival curve was flat and parallel compared to age- and sex-matched controls beyond 2 years. Multivariate analysis demonstrated the following independent factors associated with survival: renal dysfunction [hazard ratio (HR) = 3.11; 95% confidence interval (CI) = 1.44-6.73], New York Heart Association (NYHA) class ≥ III (HR = 2.25; 95% CI = 1.38-3.67), circulatory arrest time > 100 minutes (HR = 2.92; 95% CI = 1.57-5.43), peripheral vascular disease (HR = 2.44; 95% CI = 1.25-4.74), and concomitant coronary artery bypass graft operation (HR = 2.14; 95% CI = 1.20-3.80).Morbidity, mortality, and medium-term survival were not statistically different for patients undergoing elective hemi-aortic arch and total aortic arch surgery. The survival curve in this group of patients is flat and parallel to sex- and age-matched controls beyond 2 years. Multivariate analysis identified independent influences on survival as renal dysfunction, NYHA class ≥ III, circulatory arrest time (> 100 min), peripheral vascular disease, and concomitant coronary artery bypass grafting. Focus on preoperative optimization of some of these variables may positively influence long-term survival." @default.
• W2330241036 created "2016-06-24" @default.
• W2330241036 creator A5012742034 @default.
• W2330241036 creator A5031624655 @default.
• W2330241036 creator A5033307594 @default.
• W2330241036 creator A5062253375 @default.
• W2330241036 creator A5064460956 @default.
• W2330241036 creator A5084280701 @default.
• W2330241036 creator A5084609586 @default.
• W2330241036 date "2014-04-01" @default.
• W2330241036 modified "2023-10-06" @default.
• W2330241036 title "Influences on Early and Medium-Term Survival Following Surgical Repair of the Aortic Arch" @default.
• W2330241036 cites W100211326 @default.
• W2330241036 cites W1542136430 @default.
• W2330241036 cites W1857214598 @default.
• W2330241036 cites W1860083870 @default.
• W2330241036 cites W1906706858 @default.
• W2330241036 cites W1991972067 @default.
• W2330241036 cites W1993871176 @default.
• W2330241036 cites W2009836882 @default.
• W2330241036 cites W2027671610 @default.
• W2330241036 cites W2029780389 @default.
• W2330241036 cites W2040379154 @default.
• W2330241036 cites W2048619972 @default.
• W2330241036 cites W2049334300 @default.
• W2330241036 cites W2050808150 @default.
• W2330241036 cites W2054191022 @default.
• W2330241036 cites W2060188126 @default.
• W2330241036 cites W2071127301 @default.
• W2330241036 cites W2113313998 @default.
• W2330241036 cites W2133003685 @default.
• W2330241036 cites W2154145185 @default.
• W2330241036 cites W2165306195 @default.
• W2330241036 cites W2222697657 @default.
• W2330241036 cites W2613454590 @default.
• W2330241036 doi "https://doi.org/10.12945/j.aorta.2014.13-040" @default.
• W2330241036 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4682757" @default.
• W2330241036 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26798716" @default.
• W2330241036 hasPublicationYear "2014" @default.
• W2330241036 type Work @default.
• W2330241036 sameAs 2330241036 @default.
• W2330241036 citedByCount "3" @default.
• W2330241036 countsByYear W23302410362018 @default.
• W2330241036 countsByYear W23302410362019 @default.
• W2330241036 countsByYear W23302410362020 @default.
• W2330241036 crossrefType "journal-article" @default.
• W2330241036 hasAuthorship W2330241036A5012742034 @default.
• W2330241036 hasAuthorship W2330241036A5031624655 @default.
• W2330241036 hasAuthorship W2330241036A5033307594 @default.
• W2330241036 hasAuthorship W2330241036A5062253375 @default.
• W2330241036 hasAuthorship W2330241036A5064460956 @default.
• W2330241036 hasAuthorship W2330241036A5084280701 @default.
• W2330241036 hasAuthorship W2330241036A5084609586 @default.
• W2330241036 hasBestOaLocation W23302410361 @default.
• W2330241036 hasConcept C126322002 @default.
• W2330241036 hasConcept C137627325 @default.
• W2330241036 hasConcept C141071460 @default.
• W2330241036 hasConcept C146957229 @default.
• W2330241036 hasConcept C154281038 @default.
• W2330241036 hasConcept C160022790 @default.
• W2330241036 hasConcept C164705383 @default.
• W2330241036 hasConcept C2777323849 @default.
• W2330241036 hasConcept C2779980429 @default.
• W2330241036 hasConcept C2780631194 @default.
• W2330241036 hasConcept C2781285907 @default.
• W2330241036 hasConcept C71924100 @default.
• W2330241036 hasConceptScore W2330241036C126322002 @default.
• W2330241036 hasConceptScore W2330241036C137627325 @default.
• W2330241036 hasConceptScore W2330241036C141071460 @default.
• W2330241036 hasConceptScore W2330241036C146957229 @default.
• W2330241036 hasConceptScore W2330241036C154281038 @default.
• W2330241036 hasConceptScore W2330241036C160022790 @default.
• W2330241036 hasConceptScore W2330241036C164705383 @default.
• W2330241036 hasConceptScore W2330241036C2777323849 @default.
• W2330241036 hasConceptScore W2330241036C2779980429 @default.
• W2330241036 hasConceptScore W2330241036C2780631194 @default.
• W2330241036 hasConceptScore W2330241036C2781285907 @default.
• W2330241036 hasConceptScore W2330241036C71924100 @default.
• W2330241036 hasIssue "2" @default.
• W2330241036 hasLocation W23302410361 @default.
• W2330241036 hasLocation W23302410362 @default.
• W2330241036 hasLocation W23302410363 @default.
• W2330241036 hasLocation W23302410364 @default.
• W2330241036 hasOpenAccess W2330241036 @default.
• W2330241036 hasPrimaryLocation W23302410361 @default.
• W2330241036 hasRelatedWork W1973079618 @default.
• W2330241036 hasRelatedWork W2011002006 @default.
• W2330241036 hasRelatedWork W2042713126 @default.
• W2330241036 hasRelatedWork W2363695337 @default.
• W2330241036 hasRelatedWork W2412711156 @default.
• W2330241036 hasRelatedWork W2417076022 @default.
• W2330241036 hasRelatedWork W4223604533 @default.
• W2330241036 hasRelatedWork W4251337095 @default.
• W2330241036 hasRelatedWork W4308515293 @default.
• W2330241036 hasRelatedWork W2413846686 @default.
• W2330241036 hasVolume "2" @default.
• W2330241036 isParatext "false" @default.
• W2330241036 isRetracted "false" @default.

• next