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• W244868270 endingPage "504" @default.
• W244868270 startingPage "496" @default.
• W244868270 abstract "The present experiment was carried out to clarify the effect of administration of the prostaglandin F2α (PGF2α)-analogue on the luteal function and the maintenance of pregnancy in bitches. Fifty-one bitches received a single inoculation of PGF2α-analogue by intramuscular injection. The effect of this agent was observed by monitoring progesterone (P) levels and the state of the uterus by laparotomy, the occurrence of abortion, and the state of parturition. As a result, when bitches were administered with 100-400 μg at the beginning of the luteal phase, the decrease in the P level was temporary. In bitches inoculated with 100-800 μg of PGF2α-analogue at the functional luteal stage, the P level began to decrease as early as on the following day after injection. In those treated with 100-200 μg of PGF2α-analogue at 10-15 days of pregnancy, pregnancy was maintained in 3 of 5 bitches that had received the treatment at day 10, while in the remaining two, all embryos died after implantation. In those that had received the same treatment at day 15, only 2 of 7 maintained pregnancy. Pregnancy was interrupted in eight bitches treated with doses of 100-200 μg at days 25-45. In four bitches treated with doses of 100-200 μg at day 55, premature birth was induced after 30-44 hr. In conclusion, regression of the corpus luteum, abortion, and premature birth were induced in bitches treated with 100-200 μg at each stage, except the beginning of the luteal phase and of the pregnancy." @default.
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• W244868270 date "1989-01-01" @default.
• W244868270 modified "2023-10-14" @default.
• W244868270 title "Effects of prostaglandin F2.ALPHA.-analogue administration on luteal function, implantation of embryos and maintenance of pregnancy in bitches." @default.
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• W244868270 doi "https://doi.org/10.1292/jvms1939.51.496" @default.
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