Matches in SemOpenAlex for { <https://semopenalex.org/work/W2490174672> ?p ?o ?g. }
- W2490174672 abstract "Despite our increasing understanding of molecular mechanisms controlling embryogenesis, the identification and characterization of teratogenic substances still heavily relies on animal testing. Embryonic development depends on cell-autonomous and non-autonomous processes including spatiotemporally regulated extracellular signaling activities. These have been elucidated in transgenic mouse models harboring easily detectable reporter genes under the control of evolutionarily conserved signaling cascades. We propose combining these transgenic mouse models and cells derived thereof with existing alternative toxicological testing strategies. This would enable the plausibility of in vitro data to be verified in light of in vivo data and, ultimately, facilitate regulatory acceptance of in vitro test methods." @default.
- W2490174672 created "2016-08-23" @default.
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- W2490174672 date "2016-10-01" @default.
- W2490174672 modified "2023-09-27" @default.
- W2490174672 title "Transgenic Mouse Models Transferred into the Test Tube: New Perspectives for Developmental Toxicity Testing In Vitro ?" @default.
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- W2490174672 cites W1985007684 @default.
- W2490174672 cites W1985303224 @default.
- W2490174672 cites W1986813124 @default.
- W2490174672 cites W1990124144 @default.
- W2490174672 cites W1991156103 @default.
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- W2490174672 doi "https://doi.org/10.1016/j.tips.2016.06.009" @default.
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