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• W2500979587 abstract "2‐(2‐Amino‐3,5‐dinitrophenyl)‐2‐oxoacetic acid ( 2 ) was obtained from hydrolysis of 5,7‐dinitroisatin ( 1 ) in alkaline media. A novel quinoxaline derivative ( 3 ) was synthesized from the reaction of the same compound ( 1 ) with o ‐phenylenediamine. Reacting 2 with ethyl 3‐oxo‐3‐phenylpropanoate yields 6,8‐dinitro‐2‐phenylquinoline‐3,4‐dicarboxylic acid ( 4 ). Then, 4 was converted into new quinoline‐diacylchloride, quinoline‐ester, quinoline‐dicarboxamide, pyridazine, and pyrroledione derivatives ( 5 , 6a , 6b , 6c , 6d , 7a , 7b , 7c , 7d , 8 , 9 , 10a , 10b , 10c , 10d , 11a , 11b , 12 ) with SOCl 2 , alcohols, amines, and hydrazines, respectively. The structures of synthesized compounds were clarified by 1 H NMR, 13 C NMR, IR, mass and elemental analysis methods." @default.
• W2500979587 created "2016-08-23" @default.
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• W2500979587 date "2013-10-31" @default.
• W2500979587 modified "2023-10-13" @default.
• W2500979587 title "Utility of the Pfitzinger Reaction in the Synthesis of Novel Quinoline Derivatives and Related Heterocycles" @default.
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• W2500979587 doi "https://doi.org/10.1002/jhet.1607" @default.
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