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• W2555532946 startingPage "357" @default.
• W2555532946 abstract "The introduction of Ipilimumab (2011), a monoclonal antibody (mAb) binding to CTLA4, for the treatment of metastatic melanoma represents a turning point in the history of cancer therapy. This agent offers the possibility of long-term remission for a previously incurable and rapidly fatal disease. Furthermore, its novel mechanism of activating the immune system to recognize and eliminate cancer is potentially applicable to all tumors. The initial breakthrough medicines are mAbs that antagonize cell surface protein–protein interactions. This chapter outlines the basic principles of immuno-oncology, provides examples of potential drug targets, and assesses the current status of immuno-oncology small molecule drug discovery efforts for these targets." @default.
• W2555532946 created "2016-11-30" @default.
• W2555532946 creator A5014347899 @default.
• W2555532946 creator A5037776761 @default.
• W2555532946 creator A5068588644 @default.
• W2555532946 creator A5082369877 @default.
• W2555532946 date "2017-01-01" @default.
• W2555532946 modified "2023-10-16" @default.
• W2555532946 title "Cancer Immunotherapy—An Emerging Field That Bridges Oncology and Immunology Research" @default.
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