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• W2564351372 abstract "Abstract Famotidine was labeled with iodine-125 to obtain 125 I-famotidine ( 125 I-fam) as an agent for ulcer imaging. The radiochemical yield of 125 I-famotidine reached approximately 98.5 ± 0.23% at optimum conditions of pH, oxidizing agent, reaction time and the amount of substrate. 125 I-fam was stable for 48 h. Different chromatographic techniques were used to determine the radiochemical yield and purity. Intravenous biodistribution studies of 125 I-fam revealed high concentration in the stomach ulcer, reaching about 65.9 ± 0.28% of the total injected dose at 30 min post injection. This concentration of 125 I-fam in stomach ulcer makes this agent promising for stomach ulcer imaging." @default.
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• W2564351372 date "2016-12-20" @default.
• W2564351372 modified "2023-09-23" @default.
• W2564351372 title "Radioiodinated famotidine as a new highly selective radiotracer for peptic ulcer disorder detection, diagnostic nuclear imaging and biodistribution" @default.
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• W2564351372 doi "https://doi.org/10.1515/ract-2016-2683" @default.
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