FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2724528048> ?p ?o ?g. }

• W2724528048 endingPage "2432" @default.
• W2724528048 startingPage "2420" @default.
• W2724528048 abstract "BACKGROUND Hepatitis C virus (HCV) is the leading cause of severe liver disease worldwide and is highly endemic in Africa, where it often has nosocomial spread. Little is known on the HCV prevalence, risk for transfusion‐transmitted HCV, and circulating genotypes in Rwanda. This study was performed to investigate the prevalence of anti‐HCV among blood donors from all regions of the country and genetically characterize identified HCV strains. STUDY DESIGN AND METHODS Data on anti‐HCV reactivity for all 45,061 Rwandan blood donations during 2014 were compiled. Samples from 720 blood donors were reanalyzed for anti‐HCV in Sweden. Line immunoassay INNO‐LIA HCV and detection of HCV RNA by polymerase chain reaction were used to confirm anti‐HCV reactivity. The NS5B and core regions were sequenced and phylogenetic analysis was performed. RESULTS The anti‐HCV prevalence among all first‐time blood donors was 1.6%, with the highest occurrence in donors from the eastern region. On further analysis, only 25 of 120 primarily anti‐HCV–reactive samples could be confirmed reactive and 15 samples had indeterminate results by INNO‐LIA. Confirmed reactivity was more common among females than males (p = 0.03) with no regional difference. Phylogenetic analysis of the sequences showed a predominance of subtypes 4k, 4q, and 4r, with no geographical difference in their distribution. CONCLUSION The prevalence of anti‐HCV among Rwandan blood donors has probably been overestimated previously due to the high rate of nonconfirmable anti‐HCV reactivity. Further study of the involved mechanism is needed to avoid loss of blood products and distress for blood donors and other test recipients." @default.
• W2724528048 created "2017-07-14" @default.
• W2724528048 creator A5013738125 @default.
• W2724528048 creator A5054255573 @default.
• W2724528048 creator A5055221957 @default.
• W2724528048 creator A5075939124 @default.
• W2724528048 creator A5084375501 @default.
• W2724528048 creator A5088169141 @default.
• W2724528048 date "2017-07-03" @default.
• W2724528048 modified "2023-10-17" @default.
• W2724528048 title "Low prevalence of hepatitis C virus RNA in blood donors with anti‐hepatitis C virus reactivity in Rwanda" @default.
• W2724528048 cites W1494031014 @default.
• W2724528048 cites W1515594846 @default.
• W2724528048 cites W1881009043 @default.
• W2724528048 cites W1963847565 @default.
• W2724528048 cites W1970962873 @default.
• W2724528048 cites W1977300462 @default.
• W2724528048 cites W1991752162 @default.
• W2724528048 cites W2009787031 @default.
• W2724528048 cites W2010317967 @default.
• W2724528048 cites W2012124362 @default.
• W2724528048 cites W2012709249 @default.
• W2724528048 cites W2042063943 @default.
• W2724528048 cites W2045898838 @default.
• W2724528048 cites W2049624486 @default.
• W2724528048 cites W2069597046 @default.
• W2724528048 cites W2070895726 @default.
• W2724528048 cites W2073809100 @default.
• W2724528048 cites W2096347191 @default.
• W2724528048 cites W2097710336 @default.
• W2724528048 cites W2099758818 @default.
• W2724528048 cites W2106110144 @default.
• W2724528048 cites W2116256458 @default.
• W2724528048 cites W2118398497 @default.
• W2724528048 cites W2120010688 @default.
• W2724528048 cites W2133036275 @default.
• W2724528048 cites W2134750892 @default.
• W2724528048 cites W2138568618 @default.
• W2724528048 cites W2142172776 @default.
• W2724528048 cites W2142681442 @default.
• W2724528048 cites W2143523085 @default.
• W2724528048 cites W2145708303 @default.
• W2724528048 cites W2147437748 @default.
• W2724528048 cites W2207138264 @default.
• W2724528048 cites W2247637054 @default.
• W2724528048 cites W2413303725 @default.
• W2724528048 cites W2435684008 @default.
• W2724528048 cites W2467808135 @default.
• W2724528048 cites W2507635332 @default.
• W2724528048 cites W2520597593 @default.
• W2724528048 cites W2568272164 @default.
• W2724528048 doi "https://doi.org/10.1111/trf.14204" @default.
• W2724528048 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28671283" @default.
• W2724528048 hasPublicationYear "2017" @default.
• W2724528048 type Work @default.
• W2724528048 sameAs 2724528048 @default.
• W2724528048 citedByCount "9" @default.
• W2724528048 countsByYear W27245280482018 @default.
• W2724528048 countsByYear W27245280482019 @default.
• W2724528048 countsByYear W27245280482021 @default.
• W2724528048 countsByYear W27245280482022 @default.
• W2724528048 countsByYear W27245280482023 @default.
• W2724528048 crossrefType "journal-article" @default.
• W2724528048 hasAuthorship W2724528048A5013738125 @default.
• W2724528048 hasAuthorship W2724528048A5054255573 @default.
• W2724528048 hasAuthorship W2724528048A5055221957 @default.
• W2724528048 hasAuthorship W2724528048A5075939124 @default.
• W2724528048 hasAuthorship W2724528048A5084375501 @default.
• W2724528048 hasAuthorship W2724528048A5088169141 @default.
• W2724528048 hasBestOaLocation W27245280481 @default.
• W2724528048 hasConcept C104317684 @default.
• W2724528048 hasConcept C135763542 @default.
• W2724528048 hasConcept C159047783 @default.
• W2724528048 hasConcept C203014093 @default.
• W2724528048 hasConcept C2522874641 @default.
• W2724528048 hasConcept C2776029263 @default.
• W2724528048 hasConcept C2776408679 @default.
• W2724528048 hasConcept C2776455275 @default.
• W2724528048 hasConcept C2777510210 @default.
• W2724528048 hasConcept C2780014101 @default.
• W2724528048 hasConcept C2780727368 @default.
• W2724528048 hasConcept C2781426373 @default.
• W2724528048 hasConcept C2781463415 @default.
• W2724528048 hasConcept C54355233 @default.
• W2724528048 hasConcept C71924100 @default.
• W2724528048 hasConcept C86803240 @default.
• W2724528048 hasConceptScore W2724528048C104317684 @default.
• W2724528048 hasConceptScore W2724528048C135763542 @default.
• W2724528048 hasConceptScore W2724528048C159047783 @default.
• W2724528048 hasConceptScore W2724528048C203014093 @default.
• W2724528048 hasConceptScore W2724528048C2522874641 @default.
• W2724528048 hasConceptScore W2724528048C2776029263 @default.
• W2724528048 hasConceptScore W2724528048C2776408679 @default.
• W2724528048 hasConceptScore W2724528048C2776455275 @default.
• W2724528048 hasConceptScore W2724528048C2777510210 @default.
• W2724528048 hasConceptScore W2724528048C2780014101 @default.
• W2724528048 hasConceptScore W2724528048C2780727368 @default.
• W2724528048 hasConceptScore W2724528048C2781426373 @default.

• next