FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2754366909> ?p ?o ?g. }

• W2754366909 endingPage "7467" @default.
• W2754366909 startingPage "7459" @default.
• W2754366909 abstract "Periodontitis is a chronic oral inflammatory disease caused by microorganisms. Human β‑defensin‑3 (HBD‑3) is an endogenous antimicrobial peptide that inhibits a broad spectrum of microorganisms. Cell sheet technology has been widely applied in tissue and organ reconstructions. In the current study, it was aimed to investigate the anti‑inflammatory effect of periodontal tissue engineered by HBD‑3 gene‑modified periodontal ligament cell (PDLC) sheets, and to identify a suitable method of promoting the regeneration of periodontal tissues. Western blot analysis and antimicrobial tests were used to confirm the expression of HBD‑3. The effect of the cell sheets on anti‑inflammatory activity and bone remodeling in a dog model of periodontitis was demonstrated by immunohistochemistry. The results demonstrated that the transfected PDLCs stably expressed HBD‑3. Periodontal pathogens were susceptible to the antimicrobial activity of the cell sheets. In addition, the cell sheets relieved the bone resorption caused by inflammation in the in vivo model. HBD‑3 may potentially be applied in the treatment of periodontitis and may function as osteogenic promoter via its anti‑inflammatory effect." @default.
• W2754366909 created "2017-09-25" @default.
• W2754366909 creator A5008398381 @default.
• W2754366909 creator A5022728200 @default.
• W2754366909 creator A5024684580 @default.
• W2754366909 creator A5042423587 @default.
• W2754366909 creator A5083331160 @default.
• W2754366909 date "2017-05-01" @default.
• W2754366909 modified "2023-09-27" @default.
• W2754366909 title "Transplantation of periodontal ligament cell sheets expressing human β-defensin-3 promotes anti-inflammation in a canine model of periodontitis" @default.
• W2754366909 cites W1632320034 @default.
• W2754366909 cites W1976402706 @default.
• W2754366909 cites W1988459185 @default.
• W2754366909 cites W1990880480 @default.
• W2754366909 cites W1991380378 @default.
• W2754366909 cites W2000417048 @default.
• W2754366909 cites W2005255684 @default.
• W2754366909 cites W2014646480 @default.
• W2754366909 cites W2016235579 @default.
• W2754366909 cites W2021306520 @default.
• W2754366909 cites W2032883153 @default.
• W2754366909 cites W2039107163 @default.
• W2754366909 cites W2043709380 @default.
• W2754366909 cites W2048068596 @default.
• W2754366909 cites W2049358414 @default.
• W2754366909 cites W2057860375 @default.
• W2754366909 cites W2074819592 @default.
• W2754366909 cites W2082504241 @default.
• W2754366909 cites W2093158911 @default.
• W2754366909 cites W2099908438 @default.
• W2754366909 cites W2104265287 @default.
• W2754366909 cites W2115682933 @default.
• W2754366909 cites W2129867662 @default.
• W2754366909 cites W2137302297 @default.
• W2754366909 cites W2145280222 @default.
• W2754366909 cites W2155582295 @default.
• W2754366909 cites W2161180045 @default.
• W2754366909 cites W2179183038 @default.
• W2754366909 cites W2406801452 @default.
• W2754366909 cites W2729211028 @default.
• W2754366909 cites W4210956735 @default.
• W2754366909 cites W4210991094 @default.
• W2754366909 doi "https://doi.org/10.3892/mmr.2017.7514" @default.
• W2754366909 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5865878" @default.
• W2754366909 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28944821" @default.
• W2754366909 hasPublicationYear "2017" @default.
• W2754366909 type Work @default.
• W2754366909 sameAs 2754366909 @default.
• W2754366909 citedByCount "9" @default.
• W2754366909 countsByYear W27543669092018 @default.
• W2754366909 countsByYear W27543669092019 @default.
• W2754366909 countsByYear W27543669092020 @default.
• W2754366909 countsByYear W27543669092021 @default.
• W2754366909 countsByYear W27543669092022 @default.
• W2754366909 crossrefType "journal-article" @default.
• W2754366909 hasAuthorship W2754366909A5008398381 @default.
• W2754366909 hasAuthorship W2754366909A5022728200 @default.
• W2754366909 hasAuthorship W2754366909A5024684580 @default.
• W2754366909 hasAuthorship W2754366909A5042423587 @default.
• W2754366909 hasAuthorship W2754366909A5083331160 @default.
• W2754366909 hasBestOaLocation W27543669091 @default.
• W2754366909 hasConcept C126322002 @default.
• W2754366909 hasConcept C142724271 @default.
• W2754366909 hasConcept C1491633281 @default.
• W2754366909 hasConcept C199343813 @default.
• W2754366909 hasConcept C203014093 @default.
• W2754366909 hasConcept C2776914184 @default.
• W2754366909 hasConcept C2780385504 @default.
• W2754366909 hasConcept C2911091166 @default.
• W2754366909 hasConcept C41868710 @default.
• W2754366909 hasConcept C54355233 @default.
• W2754366909 hasConcept C673006 @default.
• W2754366909 hasConcept C71924100 @default.
• W2754366909 hasConcept C86803240 @default.
• W2754366909 hasConceptScore W2754366909C126322002 @default.
• W2754366909 hasConceptScore W2754366909C142724271 @default.
• W2754366909 hasConceptScore W2754366909C1491633281 @default.
• W2754366909 hasConceptScore W2754366909C199343813 @default.
• W2754366909 hasConceptScore W2754366909C203014093 @default.
• W2754366909 hasConceptScore W2754366909C2776914184 @default.
• W2754366909 hasConceptScore W2754366909C2780385504 @default.
• W2754366909 hasConceptScore W2754366909C2911091166 @default.
• W2754366909 hasConceptScore W2754366909C41868710 @default.
• W2754366909 hasConceptScore W2754366909C54355233 @default.
• W2754366909 hasConceptScore W2754366909C673006 @default.
• W2754366909 hasConceptScore W2754366909C71924100 @default.
• W2754366909 hasConceptScore W2754366909C86803240 @default.
• W2754366909 hasIssue "5" @default.
• W2754366909 hasLocation W27543669091 @default.
• W2754366909 hasLocation W27543669092 @default.
• W2754366909 hasLocation W27543669093 @default.
• W2754366909 hasLocation W27543669094 @default.
• W2754366909 hasOpenAccess W2754366909 @default.
• W2754366909 hasPrimaryLocation W27543669091 @default.
• W2754366909 hasRelatedWork W2008763094 @default.
• W2754366909 hasRelatedWork W2134238842 @default.
• W2754366909 hasRelatedWork W2138348049 @default.
• W2754366909 hasRelatedWork W2171681536 @default.

• next