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- W2754536701 endingPage "1037" @default.
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- W2754536701 abstract "Pain is both a major clinical and economic problem, affecting more people than diabetes, heart disease, and cancer combined. While a variety of prescribed or over-the-counter (OTC) medications are available for pain management, opioid medications, especially those acting on the μ-opioid receptor (μOR) and related pathways, have proven to be the most effective, despite some serious side effects including respiration depression, pruritus, dependence, and constipation. It is therefore imperative that both academia and industry develop novel μOR analgesics which retain their opioid analgesic properties but with fewer or no adverse effects. In this review we outline recent progress towards the discovery of safer opioid analgesics." @default.
- W2754536701 created "2017-09-25" @default.
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- W2754536701 creator A5053118577 @default.
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- W2754536701 date "2017-11-01" @default.
- W2754536701 modified "2023-10-03" @default.
- W2754536701 title "Designing Safer Analgesics via μ-Opioid Receptor Pathways" @default.
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- W2754536701 doi "https://doi.org/10.1016/j.tips.2017.08.004" @default.
- W2754536701 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5690544" @default.
- W2754536701 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28935293" @default.
- W2754536701 hasPublicationYear "2017" @default.
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