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• W2787103621 abstract "The aim of this study is to determine whether the saliva analysis is an alternative to routine biochemical and immunoassay analyses in patients undergoing perito - neal dialysis (PD) or hemodialysis (HD).Study group consisted of 40 healthy control, 44 PD and 44 HD patients. Routine biochemical analytes, thyroid stimulating hormone (TSH), free T3, free T4, vitamin B12, ferritin and folic acid were measured.Compared to pre-HD, urea, creatinine, uric acid, potassium levels were lower in post-HD, and calcium, magnesium, vitamin B12 levels were higher in post-HD both in saliva and serum. Positive correlations between saliva and serum were found for TSH and ferritin in control; urea, LDH, K in PD; urea, creatinine, alkaline phosphatase in pre-HD, and gamma-glutamyl transferase, iron, TSH in post-HD. There was a negative correlation only for creatine kinase and Mg in pre-HD and calcium in post-HD. In all groups, a positive correlation was found for urea, creatinine and a negative correlation was found for magnesium.Our study showed higher salivary urea and creatinine levels in patient groups, consistent with serum levels. Based on these results, salivary urea and creatinine levels may be useful in the evaluation of azotemia in dialysis patients.Cilj ove studije je da se utvrdi da li analiza salive predstavlja alternativu rutinskim biohemijskim analizama i imunoesejima kod pacijenata podvrgnutih peritonealnoj dijalizi (PD) ili hemodijalizi (HD).Grupu ispitanika činilo je 40 zdravih kontrolnih subjekata, 44 pacijenta na PD i 44 na HD. Mereni su rutinski biohemijski analiti, tireostimulišući hormon (TSH), slobodni T3, slobodni T4, vitamin B12, feritin i folna kiselina.U poređenju sa stanjem pre HD, nivoi uree, kreatinina, mokraćne kiseline, kalijuma bili su niži posle HD, dok su nivoi kalcijuma, magnezijuma, vitamina B12 bili viši posle HD kako u salivi tako i u serumu. Pozitivne korelacije između salive i seruma nađene su za TSH i feritin u kontrolnoj grupi; ureu, LDH, K u PD; ureu, kreatinin, alkalnu fosfatazu pre HD, i gama-glutamil transferazu, gvožđe, TSH posle HD. Negativna korelacija je postojala samo za kreatin-kinazu i Mg pre HD i kalcijum posle HD. U svim grupama nađena je pozitivna korelacija za ureu, kreatinin, a negativna korelacija je nađena za magnezijum.Naša studija je pokazala više nivoe uree i kreatinina u salivi u grupama pacijenata, koji su odgovarali serumskim nivoima. Ovi rezultati pokazuju da bi salivarni nivoi uree i kreatinina mogli biti korisni u proceni azotemije kod pacijenata na dijalizi." @default.
• W2787103621 created "2018-02-23" @default.
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• W2787103621 date "2018-07-01" @default.
• W2787103621 modified "2023-10-18" @default.
• W2787103621 title "Comparison of Widely Used Biochemical Analytes in the Serum and Saliva Samples of Dialysis Patients" @default.
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• W2787103621 doi "https://doi.org/10.1515/jomb-2017-0056" @default.
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