Matches in SemOpenAlex for { <https://semopenalex.org/work/W2794289478> ?p ?o ?g. }
- W2794289478 abstract "Abstract Nonthrombogenic modifications of membranes for extracorporeal membrane oxygenators (ECMOs) are of key interest. The absence of hemocompatibility of these membranes and the need of anticoagulation of patients result in severe and potentially life‐threatening complications during ECMO treatment. To address the lack of hemocompatibility of the membrane, surface modifications are developed, which act as barriers to protein adsorption on the membrane and, in this way, prevent activation of the coagulation cascade. The modifications are based on nonionic and zwitterionic polymer brushes grafted directly from poly(4‐methyl‐1‐pentene) (TPX) membranes via single electron transfer‐living radical polymerization. Notably, this work introduces the first example of well‐controlled surface‐initiated radical polymerization of zwitterionic brushes. The antifouling layers markedly increase the recalcification time (a proxy of initiation of coagulation) compared to bare TPX membranes. Furthermore, platelet and leukocyte adhesion is drastically decreased, rendering the ECMO membranes hemocompatible." @default.
- W2794289478 created "2018-03-29" @default.
- W2794289478 creator A5020329666 @default.
- W2794289478 creator A5020594243 @default.
- W2794289478 creator A5034209189 @default.
- W2794289478 creator A5053008851 @default.
- W2794289478 creator A5053191210 @default.
- W2794289478 creator A5062934365 @default.
- W2794289478 creator A5072976896 @default.
- W2794289478 date "2018-01-22" @default.
- W2794289478 modified "2023-10-18" @default.
- W2794289478 title "Improving Hemocompatibility of Membranes for Extracorporeal Membrane Oxygenators by Grafting Nonthrombogenic Polymer Brushes" @default.
- W2794289478 cites W122937650 @default.
- W2794289478 cites W1535991112 @default.
- W2794289478 cites W1561516029 @default.
- W2794289478 cites W1584501180 @default.
- W2794289478 cites W1623612942 @default.
- W2794289478 cites W1811402656 @default.
- W2794289478 cites W1905734582 @default.
- W2794289478 cites W1906750864 @default.
- W2794289478 cites W1949480416 @default.
- W2794289478 cites W1968208857 @default.
- W2794289478 cites W1970338858 @default.
- W2794289478 cites W1974389677 @default.
- W2794289478 cites W1982346641 @default.
- W2794289478 cites W1983331713 @default.
- W2794289478 cites W1992214743 @default.
- W2794289478 cites W1994923017 @default.
- W2794289478 cites W1996146845 @default.
- W2794289478 cites W2000776189 @default.
- W2794289478 cites W2000893896 @default.
- W2794289478 cites W2002025851 @default.
- W2794289478 cites W2004162102 @default.
- W2794289478 cites W2007801653 @default.
- W2794289478 cites W2008510868 @default.
- W2794289478 cites W2010536508 @default.
- W2794289478 cites W2010912616 @default.
- W2794289478 cites W2013850549 @default.
- W2794289478 cites W2018929284 @default.
- W2794289478 cites W2021310172 @default.
- W2794289478 cites W2021623392 @default.
- W2794289478 cites W2022535023 @default.
- W2794289478 cites W2025275432 @default.
- W2794289478 cites W2034520377 @default.
- W2794289478 cites W2035473373 @default.
- W2794289478 cites W2036514461 @default.
- W2794289478 cites W2042312302 @default.
- W2794289478 cites W2042583456 @default.
- W2794289478 cites W2044000481 @default.
- W2794289478 cites W2050005607 @default.
- W2794289478 cites W2050187708 @default.
- W2794289478 cites W2050488145 @default.
- W2794289478 cites W2050712731 @default.
- W2794289478 cites W2050940330 @default.
- W2794289478 cites W2052675507 @default.
- W2794289478 cites W2054093494 @default.
- W2794289478 cites W2062535319 @default.
- W2794289478 cites W2064636572 @default.
- W2794289478 cites W2065154471 @default.
- W2794289478 cites W2069661192 @default.
- W2794289478 cites W2075972713 @default.
- W2794289478 cites W2081018972 @default.
- W2794289478 cites W2081492804 @default.
- W2794289478 cites W2082043280 @default.
- W2794289478 cites W2082700989 @default.
- W2794289478 cites W2084726980 @default.
- W2794289478 cites W2085519728 @default.
- W2794289478 cites W2085783349 @default.
- W2794289478 cites W2086187944 @default.
- W2794289478 cites W2098285181 @default.
- W2794289478 cites W2108220034 @default.
- W2794289478 cites W2110418406 @default.
- W2794289478 cites W2124221712 @default.
- W2794289478 cites W2128124893 @default.
- W2794289478 cites W2129865803 @default.
- W2794289478 cites W2133696164 @default.
- W2794289478 cites W2137783186 @default.
- W2794289478 cites W2142076308 @default.
- W2794289478 cites W2143007110 @default.
- W2794289478 cites W2146146963 @default.
- W2794289478 cites W2152921610 @default.
- W2794289478 cites W2161471392 @default.
- W2794289478 cites W2276609595 @default.
- W2794289478 cites W2288497241 @default.
- W2794289478 cites W2316287488 @default.
- W2794289478 cites W2317914143 @default.
- W2794289478 cites W2324177153 @default.
- W2794289478 cites W2331169062 @default.
- W2794289478 cites W2332819645 @default.
- W2794289478 cites W2333025280 @default.
- W2794289478 cites W2414793836 @default.
- W2794289478 cites W2499671090 @default.
- W2794289478 cites W2506332706 @default.
- W2794289478 cites W2535887885 @default.
- W2794289478 cites W2561582065 @default.
- W2794289478 cites W272142055 @default.
- W2794289478 cites W2750981523 @default.
- W2794289478 cites W4249526291 @default.
- W2794289478 doi "https://doi.org/10.1002/mabi.201700359" @default.
- W2794289478 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29356355" @default.