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- W2798889330 abstract "Isolates of Fusarium oxysporum are adapted to survive a wide range of host and nonhost conditions. In addition, F. oxysporum was recently recognized as the top emerging opportunistic fungal pathogen infecting immunocompromised humans. The sensory and response networks of these fungi undoubtedly play a fundamental role in establishing the adaptability of this group. We have examined the kinomes of 12 F. oxysporum isolates and highlighted kinase families that distinguish F. oxysporum from other fungi, as well as different isolates from one another. The amplification of kinases involved in environmental signal relay and regulating downstream cellular responses clearly sets Fusarium apart from other Ascomycetes . Although the functions of many of these kinases are still unclear, their specific proliferation highlights them as a result of the evolutionary forces that have shaped this species complex and clearly marks them as targets for exploitation in order to combat disease." @default.
- W2798889330 created "2018-05-07" @default.
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- W2798889330 date "2018-06-27" @default.
- W2798889330 modified "2023-09-27" @default.
- W2798889330 title "Kinome Expansion in the Fusarium oxysporum Species Complex Driven by Accessory Chromosomes" @default.
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- W2798889330 doi "https://doi.org/10.1128/msphere.00231-18" @default.
- W2798889330 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6001611" @default.
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- W2798889330 hasPublicationYear "2018" @default.
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