FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2803433271> ?p ?o ?g. }

• W2803433271 abstract "Pierce’s disease is a major threat to grapevines caused by the bacterium Xylella fastidiosa. Although devoid of a type 3 secretion system commonly employed by bacterial pathogens to deliver effectors inside host cells, this pathogen is able to influence host parenchymal cells from the xylem lumen by secreting a battery of hydrolytic enzymes. Defining the cellular and biochemical changes induced during disease can foster the development of novel therapeutic strategies aimed at reducing the pathogen fitness and increasing plant health. To this end we investigated the transcriptional, proteomic and metabolomic responses of diseased Vitis vinifera compared to healthy plants. We found that several antioxidant strategies were induced, including the accumulation of gamma-aminobutyric acid (GABA), and polyamine metabolism, as well as iron and copper chelation, but these were insufficient to protect the plant from chronic oxidative stress and disease symptom development. Notable upregulation of phytoalexins, pathogenesis-related proteins and various aromatic acid metabolites were part of the host responses observed. Moreover, upregulation of various cell wall modification enzymes followed the proliferation of the pathogen within xylem vessels, consistent with the intensive thickening of vessels’ secondary walls observed by magnetic resonance imaging. By interpreting the molecular profile changes taking place in symptomatic tissues, we report a set of molecular markers that can be further explored to aid in disease detection, breeding for resistance, and developing therapeutics." @default.
• W2803433271 created "2018-06-01" @default.
• W2803433271 creator A5015254145 @default.
• W2803433271 creator A5021392718 @default.
• W2803433271 creator A5028903576 @default.
• W2803433271 creator A5037521623 @default.
• W2803433271 creator A5046916304 @default.
• W2803433271 creator A5072149664 @default.
• W2803433271 creator A5084103320 @default.
• W2803433271 creator A5091011677 @default.
• W2803433271 date "2018-06-08" @default.
• W2803433271 modified "2023-09-27" @default.
• W2803433271 title "Molecular Profiling of Pierce’s Disease Outlines the Response Circuitry of Vitis vinifera to Xylella fastidiosa Infection" @default.
• W2803433271 cites W1526356907 @default.
• W2803433271 cites W1531285572 @default.
• W2803433271 cites W1621670869 @default.
• W2803433271 cites W1723083414 @default.
• W2803433271 cites W1850084715 @default.
• W2803433271 cites W1968056020 @default.
• W2803433271 cites W1973456185 @default.
• W2803433271 cites W1975044934 @default.
• W2803433271 cites W1983002021 @default.
• W2803433271 cites W1984444442 @default.
• W2803433271 cites W1985587585 @default.
• W2803433271 cites W1986292144 @default.
• W2803433271 cites W1986662234 @default.
• W2803433271 cites W1989369503 @default.
• W2803433271 cites W1990105826 @default.
• W2803433271 cites W1994145712 @default.
• W2803433271 cites W1998290817 @default.
• W2803433271 cites W1999905853 @default.
• W2803433271 cites W2003265698 @default.
• W2803433271 cites W2009967509 @default.
• W2803433271 cites W2019402080 @default.
• W2803433271 cites W2020026716 @default.
• W2803433271 cites W2022755028 @default.
• W2803433271 cites W2022983919 @default.
• W2803433271 cites W2035276838 @default.
• W2803433271 cites W2038089738 @default.
• W2803433271 cites W2040879655 @default.
• W2803433271 cites W2063888937 @default.
• W2803433271 cites W2067886035 @default.
• W2803433271 cites W2072277816 @default.
• W2803433271 cites W2073319037 @default.
• W2803433271 cites W2073769445 @default.
• W2803433271 cites W2078466815 @default.
• W2803433271 cites W2081090935 @default.
• W2803433271 cites W2082006641 @default.
• W2803433271 cites W2088790569 @default.
• W2803433271 cites W2097446697 @default.
• W2803433271 cites W2098832713 @default.
• W2803433271 cites W2102154098 @default.
• W2803433271 cites W2106530784 @default.
• W2803433271 cites W2106780701 @default.
• W2803433271 cites W2111479128 @default.
• W2803433271 cites W2114104545 @default.
• W2803433271 cites W2119166075 @default.
• W2803433271 cites W2125504032 @default.
• W2803433271 cites W2126191743 @default.
• W2803433271 cites W2133538832 @default.
• W2803433271 cites W2146890648 @default.
• W2803433271 cites W2148272131 @default.
• W2803433271 cites W2156462622 @default.
• W2803433271 cites W2158804744 @default.
• W2803433271 cites W2160458586 @default.
• W2803433271 cites W2167417738 @default.
• W2803433271 cites W2167736573 @default.
• W2803433271 cites W2168302624 @default.
• W2803433271 cites W2170551349 @default.
• W2803433271 cites W2211341584 @default.
• W2803433271 cites W2223549218 @default.
• W2803433271 cites W2271011195 @default.
• W2803433271 cites W2287623666 @default.
• W2803433271 cites W2311871742 @default.
• W2803433271 cites W2319896479 @default.
• W2803433271 cites W2331748692 @default.
• W2803433271 cites W2402566654 @default.
• W2803433271 cites W2471411197 @default.
• W2803433271 cites W2496220225 @default.
• W2803433271 cites W2521662433 @default.
• W2803433271 cites W2578996068 @default.
• W2803433271 cites W2599661594 @default.
• W2803433271 cites W2786154825 @default.
• W2803433271 cites W4237809070 @default.
• W2803433271 cites W4285719527 @default.
• W2803433271 doi "https://doi.org/10.3389/fpls.2018.00771" @default.
• W2803433271 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6002507" @default.
• W2803433271 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29937771" @default.
• W2803433271 hasPublicationYear "2018" @default.
• W2803433271 type Work @default.
• W2803433271 sameAs 2803433271 @default.
• W2803433271 citedByCount "27" @default.
• W2803433271 countsByYear W28034332712018 @default.
• W2803433271 countsByYear W28034332712019 @default.
• W2803433271 countsByYear W28034332712020 @default.
• W2803433271 countsByYear W28034332712021 @default.
• W2803433271 countsByYear W28034332712022 @default.
• W2803433271 countsByYear W28034332712023 @default.
• W2803433271 crossrefType "journal-article" @default.
• W2803433271 hasAuthorship W2803433271A5015254145 @default.

• next