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• W2805088892 abstract "Metastatic or relapsed angiosarcoma has a poor prognosis and the efficacy of conventional chemotherapy is often limited. Apatinib, a novel tyrosine kinase inhibitor (TKI) targeting vascular endothelial growth factor receptor-2 (VEGFR2), has been approved for the treatment of advanced gastric cancer. Herein, we report a patient with advanced angiosarcoma, who received apatinib at a daily dose of 250 to 725 mg, resulting in a partial response for three months, which may be related to Kinase Insert Domain Receptor (KDR) gene amplification. Our experience reported here indicated that apatinib may be a useful therapeutic option for treatment of patients with advanced angiosarcoma." @default.
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• W2805088892 date "2018-05-31" @default.
• W2805088892 modified "2023-10-17" @default.
• W2805088892 title "Apatinib treatment for KIT- and KDR-amplified angiosarcoma: a case report" @default.
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• W2805088892 doi "https://doi.org/10.1186/s12885-018-4523-2" @default.
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