FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2810139938> ?p ?o ?g. }

• W2810139938 endingPage "e469" @default.
• W2810139938 startingPage "e462" @default.
• W2810139938 abstract "Background: Clubfoot is a common congenital anomaly with multiple potential risk factors. Identification of modifiable risk factors may minimize future incidence of clubfoot. The aim of this meta-analysis was to systematically review and analyze the best clinical evidence regarding risk factors associated with clubfoot. Methods: Medline, Embase, and Cochrane databases were systematically searched from 1967 to May 11, 2016 for studies reporting risk factors for clubfoot. Randomized trials and observational studies were eligible for inclusion, and assessed in duplicate. Study quality was assessed with the Newcastle-Ottawa Scale or Cochrane risk of bias tool; low quality studies were excluded, all randomized trials were included. Two reviewers extracted data independently. This meta-analysis was conducted in accordance with PRISMA guidelines. Pooled effect estimates for the odds of clubfoot were calculated using random or fixed-effects models based on heterogeneity. Results: Forty-two studies (28 case-control, 10 cohort, 4 randomized trials) comprising 31,844 clubfoot cases and 6,604,013 controls were included. Risk factors associated with increased odds of clubfoot included maternal smoking [odds ratio (OR)=1.65; 95% confidence interval (CI), 1.54-1.78], paternal smoking (OR=1.72; 95% CI, 1.05-2.84), maternal body mass index >30 (OR=1.46; 95% CI, 1.29-1.65), family history (OR=7.80; 95% CI, 4.04-15.04), amniocentesis (OR=2.08; 95% CI, 1.34-3.21), selective serotonin reuptake inhibitor exposure (OR=1.78; 95% CI, 1.34-2.37) maternal single status (OR=1.17; 95% CI, 1.11-1.23), gestational diabetes (OR=1.40; 95% CI, 1.13-1.72), nulliparity (OR=1.32; 95% CI, 1.19-1.45), male sex (OR=1.68; 95% CI, 1.48-1.94), and aboriginal Australian race (OR=2.35; 95% CI, 1.63-3.38). Conclusions: Smoking, maternal obesity, family history, amniocentesis, and some selective serotonin reuptake inhibitor exposures are the most clinically relevant exposures associated with increased odds of clubfoot, with family history representing the greatest risk. Recognition of modifiable risk factors may help in counseling patients, and minimizing clubfoot incidence. Level of Evidence: Level II." @default.
• W2810139938 created "2018-07-10" @default.
• W2810139938 creator A5007105066 @default.
• W2810139938 creator A5010771835 @default.
• W2810139938 creator A5031506995 @default.
• W2810139938 creator A5041571206 @default.
• W2810139938 creator A5044629732 @default.
• W2810139938 creator A5067640153 @default.
• W2810139938 date "2018-09-01" @default.
• W2810139938 modified "2023-10-09" @default.
• W2810139938 title "Clubfoot Etiology: A Meta-Analysis and Systematic Review of Observational and Randomized Trials" @default.
• W2810139938 cites W1542278706 @default.
• W2810139938 cites W1849790101 @default.
• W2810139938 cites W1866814291 @default.
• W2810139938 cites W1917624945 @default.
• W2810139938 cites W1964334498 @default.
• W2810139938 cites W1968660943 @default.
• W2810139938 cites W1970712275 @default.
• W2810139938 cites W1976065070 @default.
• W2810139938 cites W1978332054 @default.
• W2810139938 cites W1978351931 @default.
• W2810139938 cites W1979773486 @default.
• W2810139938 cites W1981640001 @default.
• W2810139938 cites W1985513433 @default.
• W2810139938 cites W1995607200 @default.
• W2810139938 cites W1997491570 @default.
• W2810139938 cites W2019039076 @default.
• W2810139938 cites W2019746422 @default.
• W2810139938 cites W2026042308 @default.
• W2810139938 cites W2036668716 @default.
• W2810139938 cites W2042496376 @default.
• W2810139938 cites W2043073846 @default.
• W2810139938 cites W2045204838 @default.
• W2810139938 cites W2046925315 @default.
• W2810139938 cites W2054268328 @default.
• W2810139938 cites W2057537068 @default.
• W2810139938 cites W2062240933 @default.
• W2810139938 cites W2062348222 @default.
• W2810139938 cites W2063287476 @default.
• W2810139938 cites W2064066659 @default.
• W2810139938 cites W2064346773 @default.
• W2810139938 cites W2065668769 @default.
• W2810139938 cites W2066048508 @default.
• W2810139938 cites W2071658829 @default.
• W2810139938 cites W2077097882 @default.
• W2810139938 cites W2092264828 @default.
• W2810139938 cites W2094865845 @default.
• W2810139938 cites W2095924616 @default.
• W2810139938 cites W2100717646 @default.
• W2810139938 cites W2103044944 @default.
• W2810139938 cites W2103515441 @default.
• W2810139938 cites W2105787554 @default.
• W2810139938 cites W2111286338 @default.
• W2810139938 cites W2113801080 @default.
• W2810139938 cites W2126350559 @default.
• W2810139938 cites W2128496895 @default.
• W2810139938 cites W2132966541 @default.
• W2810139938 cites W2150089027 @default.
• W2810139938 cites W2168557507 @default.
• W2810139938 cites W2168922114 @default.
• W2810139938 cites W2180705671 @default.
• W2810139938 cites W2281733839 @default.
• W2810139938 cites W2297477869 @default.
• W2810139938 cites W2298222525 @default.
• W2810139938 cites W2322295361 @default.
• W2810139938 cites W2333543920 @default.
• W2810139938 cites W2334484285 @default.
• W2810139938 cites W2386782607 @default.
• W2810139938 cites W2473931391 @default.
• W2810139938 cites W273964938 @default.
• W2810139938 cites W2950622697 @default.
• W2810139938 cites W4236738052 @default.
• W2810139938 cites W4244314296 @default.
• W2810139938 cites W4246134835 @default.
• W2810139938 doi "https://doi.org/10.1097/bpo.0000000000001191" @default.
• W2810139938 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29917009" @default.
• W2810139938 hasPublicationYear "2018" @default.
• W2810139938 type Work @default.
• W2810139938 sameAs 2810139938 @default.
• W2810139938 citedByCount "33" @default.
• W2810139938 countsByYear W28101399382019 @default.
• W2810139938 countsByYear W28101399382020 @default.
• W2810139938 countsByYear W28101399382021 @default.
• W2810139938 countsByYear W28101399382022 @default.
• W2810139938 countsByYear W28101399382023 @default.
• W2810139938 crossrefType "journal-article" @default.
• W2810139938 hasAuthorship W2810139938A5007105066 @default.
• W2810139938 hasAuthorship W2810139938A5010771835 @default.
• W2810139938 hasAuthorship W2810139938A5031506995 @default.
• W2810139938 hasAuthorship W2810139938A5041571206 @default.
• W2810139938 hasAuthorship W2810139938A5044629732 @default.
• W2810139938 hasAuthorship W2810139938A5067640153 @default.
• W2810139938 hasConcept C126322002 @default.
• W2810139938 hasConcept C141071460 @default.
• W2810139938 hasConcept C156957248 @default.
• W2810139938 hasConcept C168563851 @default.
• W2810139938 hasConcept C187212893 @default.
• W2810139938 hasConcept C23131810 @default.

• next