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- W2893669826 abstract "Endometriosis is an estrogen-dependent, progesterone-resistant, inflammatory disease with symptoms that include pelvic pain, infertility, and compromised quality of life in millions of women worldwide. Approximately 50% of the risk of developing endometriosis is due to genetic factors with the remaining 50% due to environmental (i.e., exposome) causes. Treatments are hormonal, surgical, or both, with limited efficacy in the long term. Diagnosis of pelvic endometriosis is through visual identification and confirmatory histopathology of lesions. Recent innovations in genomics, genetics and epigenetics, molecular and cell biology, imaging, and a worldwide effort to standardize patient phenotyping and biospecimen collection have contributed to understanding mechanisms underlying the pathogenesis and pathophysiology of endometriosis. Furthermore, integration of “big data” obtained through these technologies holds great promise for novel targeted therapies, noninvasive diagnostics, and prognostic indicators. This chapter reviews current advances in genomics, genetics, and epigenetics of endometriosis that are providing translational approaches for preventing, diagnosing, and effectively treating this enigmatic disease." @default.
- W2893669826 created "2018-10-05" @default.
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- W2893669826 date "2019-01-01" @default.
- W2893669826 modified "2023-10-18" @default.
- W2893669826 title "Genetics and Genomics of Endometriosis" @default.
- W2893669826 cites W144423133 @default.
- W2893669826 cites W1513717411 @default.
- W2893669826 cites W1594350035 @default.
- W2893669826 cites W1744127096 @default.
- W2893669826 cites W1885849841 @default.
- W2893669826 cites W1908598451 @default.
- W2893669826 cites W1947692703 @default.
- W2893669826 cites W1964106075 @default.
- W2893669826 cites W1972640183 @default.
- W2893669826 cites W1974053954 @default.
- W2893669826 cites W1976214975 @default.
- W2893669826 cites W1982948669 @default.
- W2893669826 cites W1984211786 @default.
- W2893669826 cites W1984413516 @default.
- W2893669826 cites W1986914259 @default.
- W2893669826 cites W1988817794 @default.
- W2893669826 cites W1993162436 @default.
- W2893669826 cites W1993925306 @default.
- W2893669826 cites W1994878657 @default.
- W2893669826 cites W2000311445 @default.
- W2893669826 cites W2001524362 @default.
- W2893669826 cites W2004242608 @default.
- W2893669826 cites W2004442355 @default.
- W2893669826 cites W2007347214 @default.
- W2893669826 cites W2007359876 @default.
- W2893669826 cites W2008978345 @default.
- W2893669826 cites W2009015643 @default.
- W2893669826 cites W2012650501 @default.
- W2893669826 cites W2020639636 @default.
- W2893669826 cites W2021270230 @default.
- W2893669826 cites W2026056052 @default.
- W2893669826 cites W2027489327 @default.
- W2893669826 cites W2033961624 @default.
- W2893669826 cites W2034852369 @default.
- W2893669826 cites W2044038984 @default.
- W2893669826 cites W2045663983 @default.
- W2893669826 cites W2048280620 @default.
- W2893669826 cites W2049790971 @default.
- W2893669826 cites W2050152897 @default.
- W2893669826 cites W2051994829 @default.
- W2893669826 cites W2052734212 @default.
- W2893669826 cites W2054798875 @default.
- W2893669826 cites W2055716477 @default.
- W2893669826 cites W2056128773 @default.
- W2893669826 cites W2057436775 @default.
- W2893669826 cites W2062495971 @default.
- W2893669826 cites W2064286496 @default.
- W2893669826 cites W2069092181 @default.
- W2893669826 cites W2071667212 @default.
- W2893669826 cites W2074230554 @default.
- W2893669826 cites W2074400318 @default.
- W2893669826 cites W2076128837 @default.
- W2893669826 cites W2076213656 @default.
- W2893669826 cites W2077405130 @default.
- W2893669826 cites W2093865824 @default.
- W2893669826 cites W2095891594 @default.
- W2893669826 cites W2097313599 @default.
- W2893669826 cites W2108178559 @default.
- W2893669826 cites W2113280294 @default.
- W2893669826 cites W2114673109 @default.
- W2893669826 cites W2116069971 @default.
- W2893669826 cites W2119663632 @default.
- W2893669826 cites W2121091987 @default.
- W2893669826 cites W2121440326 @default.
- W2893669826 cites W2121772019 @default.
- W2893669826 cites W2122039871 @default.
- W2893669826 cites W2122501446 @default.
- W2893669826 cites W2123971761 @default.
- W2893669826 cites W2124424570 @default.
- W2893669826 cites W2128590024 @default.
- W2893669826 cites W2130359564 @default.
- W2893669826 cites W2133738594 @default.
- W2893669826 cites W2138664009 @default.
- W2893669826 cites W2141380825 @default.
- W2893669826 cites W2141948830 @default.
- W2893669826 cites W2143658931 @default.
- W2893669826 cites W2144772612 @default.
- W2893669826 cites W2145383112 @default.
- W2893669826 cites W2147524392 @default.
- W2893669826 cites W2147618659 @default.
- W2893669826 cites W2150404274 @default.
- W2893669826 cites W2150684041 @default.
- W2893669826 cites W2151934245 @default.
- W2893669826 cites W2158134092 @default.
- W2893669826 cites W2159517888 @default.