Matches in SemOpenAlex for { <https://semopenalex.org/work/W2905067541> ?p ?o ?g. }
- W2905067541 endingPage "435" @default.
- W2905067541 startingPage "427" @default.
- W2905067541 abstract "Pediatric recipients of liver transplantation (LT) often report lower Health-Related Quality of Life (HRQOL) than healthy controls when assessed on generic HRQOL measurement tools. The recent addition of the Pediatric Liver Transplant Quality of Life (PeLTQL), a novel disease-specific HRQOL instrument for pediatric LT recipients, into the clinical armamentarium of tools now routinely available to clinical care teams, provides the unique opportunity to identify disease-related challenges in children who have undergone this life-saving intervention. This study assesses HRQOL in pre-adolescent aged patients with a primary diagnosis of biliary atresia (BA) who underwent LT as an infant, using both generic and disease-specific HRQOL instruments validated for children. We also examined modifiable factors associated with HRQOL after pediatric LT.HRQOL was the primary outcome of this study assessed using the disease-specific PeLTQL and the generic Pediatric Quality of Life Inventory 4.0 (PedsQL). Exposure variables of interest included medication status (e.g., monotherapy, dual therapy) and participation in sports.A total of 70 (56% female, mean age 9.89 ± 1.25 years) pediatric LT recipients (mean interval since LT was 9.0 ± 1.26 years) comprised the study cohort. LT recipients reported significantly lower PedsQL Scores relative to the general population. Immunosuppression monotherapy was associated with higher patient-reported PeLTQL Scores, and sports participation was associated with higher parent-reported PedsQL Scores.Pre-adolescents who underwent LT as an infant with BA, self-report low HRQOL on both disease-specific and generic HRQOL tools. Further research targeting sports participation and simplifying immunosuppression may further optimize quality of life years restored by life-saving LT." @default.
- W2905067541 created "2018-12-22" @default.
- W2905067541 creator A5003219968 @default.
- W2905067541 creator A5009726520 @default.
- W2905067541 creator A5012844484 @default.
- W2905067541 creator A5018583602 @default.
- W2905067541 creator A5019018783 @default.
- W2905067541 creator A5033236189 @default.
- W2905067541 creator A5042246134 @default.
- W2905067541 creator A5044332612 @default.
- W2905067541 creator A5050927122 @default.
- W2905067541 creator A5055875110 @default.
- W2905067541 creator A5066761281 @default.
- W2905067541 creator A5073711492 @default.
- W2905067541 creator A5077282683 @default.
- W2905067541 creator A5080026904 @default.
- W2905067541 date "2019-08-01" @default.
- W2905067541 modified "2023-10-04" @default.
- W2905067541 title "Health-related quality of life in pre-adolescent liver transplant recipients with biliary atresia: A cross-sectional study" @default.
- W2905067541 cites W1492442540 @default.
- W2905067541 cites W1604323897 @default.
- W2905067541 cites W1967393185 @default.
- W2905067541 cites W1976099340 @default.
- W2905067541 cites W1982893182 @default.
- W2905067541 cites W1983713464 @default.
- W2905067541 cites W2010424626 @default.
- W2905067541 cites W2012850164 @default.
- W2905067541 cites W2013212520 @default.
- W2905067541 cites W2031668210 @default.
- W2905067541 cites W2033513592 @default.
- W2905067541 cites W2038805298 @default.
- W2905067541 cites W2047227164 @default.
- W2905067541 cites W2050878694 @default.
- W2905067541 cites W2067724039 @default.
- W2905067541 cites W2077975927 @default.
- W2905067541 cites W2087418814 @default.
- W2905067541 cites W2087721390 @default.
- W2905067541 cites W2100627026 @default.
- W2905067541 cites W2104790602 @default.
- W2905067541 cites W2122681878 @default.
- W2905067541 cites W2125103893 @default.
- W2905067541 cites W2150292700 @default.
- W2905067541 cites W2156702515 @default.
- W2905067541 cites W2254456561 @default.
- W2905067541 cites W2323149989 @default.
- W2905067541 cites W2565294627 @default.
- W2905067541 cites W2587671257 @default.
- W2905067541 cites W2596378384 @default.
- W2905067541 cites W2599884304 @default.
- W2905067541 cites W2761821607 @default.
- W2905067541 doi "https://doi.org/10.1016/j.clinre.2018.10.018" @default.
- W2905067541 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30528863" @default.
- W2905067541 hasPublicationYear "2019" @default.
- W2905067541 type Work @default.
- W2905067541 sameAs 2905067541 @default.
- W2905067541 citedByCount "11" @default.
- W2905067541 countsByYear W29050675412020 @default.
- W2905067541 countsByYear W29050675412021 @default.
- W2905067541 countsByYear W29050675412022 @default.
- W2905067541 crossrefType "journal-article" @default.
- W2905067541 hasAuthorship W2905067541A5003219968 @default.
- W2905067541 hasAuthorship W2905067541A5009726520 @default.
- W2905067541 hasAuthorship W2905067541A5012844484 @default.
- W2905067541 hasAuthorship W2905067541A5018583602 @default.
- W2905067541 hasAuthorship W2905067541A5019018783 @default.
- W2905067541 hasAuthorship W2905067541A5033236189 @default.
- W2905067541 hasAuthorship W2905067541A5042246134 @default.
- W2905067541 hasAuthorship W2905067541A5044332612 @default.
- W2905067541 hasAuthorship W2905067541A5050927122 @default.
- W2905067541 hasAuthorship W2905067541A5055875110 @default.
- W2905067541 hasAuthorship W2905067541A5066761281 @default.
- W2905067541 hasAuthorship W2905067541A5073711492 @default.
- W2905067541 hasAuthorship W2905067541A5077282683 @default.
- W2905067541 hasAuthorship W2905067541A5080026904 @default.
- W2905067541 hasConcept C126322002 @default.
- W2905067541 hasConcept C142052008 @default.
- W2905067541 hasConcept C142724271 @default.
- W2905067541 hasConcept C159110408 @default.
- W2905067541 hasConcept C1862650 @default.
- W2905067541 hasConcept C187212893 @default.
- W2905067541 hasConcept C2777075537 @default.
- W2905067541 hasConcept C2779134260 @default.
- W2905067541 hasConcept C2779243279 @default.
- W2905067541 hasConcept C2779609443 @default.
- W2905067541 hasConcept C2779951463 @default.
- W2905067541 hasConcept C2780252810 @default.
- W2905067541 hasConcept C2908647359 @default.
- W2905067541 hasConcept C2911091166 @default.
- W2905067541 hasConcept C71924100 @default.
- W2905067541 hasConcept C72563966 @default.
- W2905067541 hasConcept C99454951 @default.
- W2905067541 hasConceptScore W2905067541C126322002 @default.
- W2905067541 hasConceptScore W2905067541C142052008 @default.
- W2905067541 hasConceptScore W2905067541C142724271 @default.
- W2905067541 hasConceptScore W2905067541C159110408 @default.
- W2905067541 hasConceptScore W2905067541C1862650 @default.
- W2905067541 hasConceptScore W2905067541C187212893 @default.
- W2905067541 hasConceptScore W2905067541C2777075537 @default.