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- W2912441054 abstract "Although solution-state NMR is frequently used in metrologically-traceable quantification studies, this is not the case for solid-state NMR. However, solid-state NMR allows quantification of substances without the need of dissolution, providing a truly non-destructive approach, and extending metrologically-traceable quantitative NMR to sample classes that are difficult to characterize in solution. In this contribution we present a thorough and rigorous protocol for 19F quantitative solid-state NMR employing a certified reference material as external calibrant to provide metrological traceability to absolutely quantify the content of trifluoroacetic acid (TFA) in a peptide sample, typically the major impurity in synthetic peptides. The protocol includes determining the quantitative volume of the solid-state NMR sample holder (rotor), the ERETIC (electronic reference to access in vivo concentrations) method (Akoka et al 1999 Anal. Chem. 71 2554) to compensate for variations in the sensitivity of the radio frequency resonant circuit when an external calibrant is used, and the EASY (elimination of artefacts in NMR spectroscopy) method (Jaeger and Hemmann 2014 Solid State Nucl. Magn. Reson. 57–58 22) to effectively suppress the 19F NMR background signal from the probe head. We applied the protocol to quantify the amount of TFA in a candidate NRC certified reference material of the peptide angiotensin II. The results obtained by 19F quantitative solid-state NMR are in excellent agreement with those obtained by quantitative NMR in solution employing an internal calibrant." @default.
- W2912441054 created "2019-02-21" @default.
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- W2912441054 date "2019-02-22" @default.
- W2912441054 modified "2023-09-25" @default.
- W2912441054 title "Metrologically traceable quantification of trifluoroacetic acid content in peptide reference materials by<sup>19</sup>F solid-state NMR" @default.
- W2912441054 cites W1504366750 @default.
- W2912441054 cites W181801465 @default.
- W2912441054 cites W1967998310 @default.
- W2912441054 cites W1974836081 @default.
- W2912441054 cites W1975340444 @default.
- W2912441054 cites W1975475877 @default.
- W2912441054 cites W1975486119 @default.
- W2912441054 cites W1975487233 @default.
- W2912441054 cites W1977390000 @default.
- W2912441054 cites W1977579538 @default.
- W2912441054 cites W1989031948 @default.
- W2912441054 cites W1989307669 @default.
- W2912441054 cites W1990889829 @default.
- W2912441054 cites W1995783473 @default.
- W2912441054 cites W1996659214 @default.
- W2912441054 cites W1997041219 @default.
- W2912441054 cites W2006710432 @default.
- W2912441054 cites W2014453289 @default.
- W2912441054 cites W2014774696 @default.
- W2912441054 cites W2018230358 @default.
- W2912441054 cites W2018437153 @default.
- W2912441054 cites W2019037456 @default.
- W2912441054 cites W2022635032 @default.
- W2912441054 cites W2023665676 @default.
- W2912441054 cites W2024903534 @default.
- W2912441054 cites W2033057757 @default.
- W2912441054 cites W2037723020 @default.
- W2912441054 cites W2044577973 @default.
- W2912441054 cites W2045722971 @default.
- W2912441054 cites W2045925085 @default.
- W2912441054 cites W2046090790 @default.
- W2912441054 cites W2046152748 @default.
- W2912441054 cites W2046520841 @default.
- W2912441054 cites W2049104354 @default.
- W2912441054 cites W2050020004 @default.
- W2912441054 cites W2052665099 @default.
- W2912441054 cites W2056702184 @default.
- W2912441054 cites W2058740696 @default.
- W2912441054 cites W2062311136 @default.
- W2912441054 cites W2063958263 @default.
- W2912441054 cites W2064436757 @default.
- W2912441054 cites W2064625584 @default.
- W2912441054 cites W2065497396 @default.
- W2912441054 cites W2066271048 @default.
- W2912441054 cites W2066467192 @default.
- W2912441054 cites W2069086753 @default.
- W2912441054 cites W2070041260 @default.
- W2912441054 cites W2073467704 @default.
- W2912441054 cites W2075094446 @default.
- W2912441054 cites W2078148933 @default.
- W2912441054 cites W2083850254 @default.
- W2912441054 cites W2084402667 @default.
- W2912441054 cites W2089976987 @default.
- W2912441054 cites W2090105949 @default.
- W2912441054 cites W2097231210 @default.
- W2912441054 cites W2109199498 @default.
- W2912441054 cites W2112688502 @default.
- W2912441054 cites W2114220158 @default.
- W2912441054 cites W2128671350 @default.
- W2912441054 cites W2149658002 @default.
- W2912441054 cites W2154804998 @default.
- W2912441054 cites W2264053766 @default.
- W2912441054 cites W2317714363 @default.
- W2912441054 cites W2332879618 @default.
- W2912441054 cites W2407944512 @default.
- W2912441054 cites W2466094451 @default.
- W2912441054 cites W2493820728 @default.
- W2912441054 cites W2500892625 @default.
- W2912441054 cites W2589472505 @default.
- W2912441054 cites W2597218406 @default.
- W2912441054 cites W2734386027 @default.
- W2912441054 cites W2769780115 @default.
- W2912441054 cites W2888487410 @default.
- W2912441054 cites W2888607831 @default.
- W2912441054 cites W2897335047 @default.
- W2912441054 cites W2905045730 @default.
- W2912441054 cites W4230713808 @default.
- W2912441054 cites W4240506054 @default.
- W2912441054 doi "https://doi.org/10.1088/1681-7575/ab04e3" @default.
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