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• W2912561621 abstract "Microscopic polyangiitis (MPA) is a rare autoimmune disease causing necrotizing small vessel vasculitis and glomerulonephritis. In addition to general nonspecific symptoms, renal and pulmonary involvement with organ dysfunction are frequent and may cause severe morbidity and mortality. Any organ system may be affected by the vasculitic process with a variety of additional clinical manifestations. Most patients have antineutrophil cytoplasmic antibodies (ANCA) and these autoantibodies are considered important in the pathophysiology. Immunosuppressive therapy with cyclophosphamide and corticosteroids is highly effective but not without risks, and induce remission in most patients. Maintenance immunosuppression is instituted for reducing relapses of vasculitic activity." @default.
• W2912561621 created "2019-02-21" @default.
• W2912561621 creator A5032246543 @default.
• W2912561621 date "2012-05-03" @default.
• W2912561621 modified "2023-10-14" @default.
• W2912561621 title "Microscopic Polyangiitis" @default.
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• W2912561621 doi "https://doi.org/10.1002/9781118355244.ch21" @default.
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