Matches in SemOpenAlex for { <https://semopenalex.org/work/W2913305810> ?p ?o ?g. }
- W2913305810 abstract "Great progress has been made in the therapeutic strategies of multiple diseases that lack curative treatments with the transplantation of mesenchymal stem cells (MSC), such as in onco-hematological diseases, myocardial infarction (MI), cerebrovascular diseases, degenerative diseases of the nervous system (multiple sclerosis, Alzheimer’s disease), and diseases of the immune system, among others. Stem cells (SC) participate in the biological processes of tissue regeneration and repair through cell replication. Recently, the beneficial therapeutic effects of SCs that are generated by the release of proteins with paracrine actions and not by cell differentiation are more well known, and 80% of the therapeutic effect of SC is attributed to paracrine actions. The MSCs release large amounts of proteins and growth factors (GF), nucleic acids, proteasomes, exosomes, and microRNA, and membrane vesicles known as the secretome are released into the extracellular space, regulating multiple biological processes. Currently, the therapeutic strategies in tissue engineering (TE) and regenerative medicine (RM) are focused on the management of products derived from cells that act, both locally and remotely, in the affected tissue or organ, achieving regenerative actions. The application of new knowledge of the secretome initiates a change in the paradigm of regenerative therapy by knowing more about and using cell products derived from cells as a “factory” for biological drugs." @default.
- W2913305810 created "2019-02-21" @default.
- W2913305810 creator A5022880024 @default.
- W2913305810 creator A5029180656 @default.
- W2913305810 creator A5029509282 @default.
- W2913305810 creator A5065525353 @default.
- W2913305810 creator A5068702152 @default.
- W2913305810 date "2019-01-23" @default.
- W2913305810 modified "2023-09-26" @default.
- W2913305810 title "Therapeutic Strategies of Secretome of Mesenchymal Stem Cell" @default.
- W2913305810 cites W1490526869 @default.
- W2913305810 cites W1571387405 @default.
- W2913305810 cites W1972694890 @default.
- W2913305810 cites W1974506577 @default.
- W2913305810 cites W1986321004 @default.
- W2913305810 cites W1988249798 @default.
- W2913305810 cites W1994686590 @default.
- W2913305810 cites W2000115558 @default.
- W2913305810 cites W2016834327 @default.
- W2913305810 cites W2018106032 @default.
- W2913305810 cites W2018258390 @default.
- W2913305810 cites W2019081320 @default.
- W2913305810 cites W2020992406 @default.
- W2913305810 cites W2025371271 @default.
- W2913305810 cites W2035844407 @default.
- W2913305810 cites W2039109621 @default.
- W2913305810 cites W2051825245 @default.
- W2913305810 cites W2052344110 @default.
- W2913305810 cites W2052687049 @default.
- W2913305810 cites W2054410308 @default.
- W2913305810 cites W2056510698 @default.
- W2913305810 cites W2060738125 @default.
- W2913305810 cites W2067024175 @default.
- W2913305810 cites W2074420452 @default.
- W2913305810 cites W2076491580 @default.
- W2913305810 cites W2081191481 @default.
- W2913305810 cites W2086914356 @default.
- W2913305810 cites W2091618419 @default.
- W2913305810 cites W2098234863 @default.
- W2913305810 cites W2098259366 @default.
- W2913305810 cites W2102085111 @default.
- W2913305810 cites W2106111979 @default.
- W2913305810 cites W2108881298 @default.
- W2913305810 cites W2110576880 @default.
- W2913305810 cites W2111004371 @default.
- W2913305810 cites W2115093090 @default.
- W2913305810 cites W2116843487 @default.
- W2913305810 cites W2118934189 @default.
- W2913305810 cites W2121882633 @default.
- W2913305810 cites W2122099309 @default.
- W2913305810 cites W2123771262 @default.
- W2913305810 cites W2129396577 @default.
- W2913305810 cites W2147083075 @default.
- W2913305810 cites W2155401787 @default.
- W2913305810 cites W2156930945 @default.
- W2913305810 cites W2163260113 @default.
- W2913305810 cites W2170852633 @default.
- W2913305810 cites W2171067954 @default.
- W2913305810 cites W2171261585 @default.
- W2913305810 cites W2197714088 @default.
- W2913305810 cites W2203046332 @default.
- W2913305810 cites W2220182948 @default.
- W2913305810 cites W2235029947 @default.
- W2913305810 cites W2281134225 @default.
- W2913305810 cites W2289101307 @default.
- W2913305810 cites W2289635694 @default.
- W2913305810 cites W2296538017 @default.
- W2913305810 cites W2312836697 @default.
- W2913305810 cites W2344378731 @default.
- W2913305810 cites W2519218117 @default.
- W2913305810 cites W2526181526 @default.
- W2913305810 cites W2555060163 @default.
- W2913305810 cites W2564450069 @default.
- W2913305810 cites W2586399067 @default.
- W2913305810 cites W2587850954 @default.
- W2913305810 cites W2593611230 @default.
- W2913305810 cites W2605484523 @default.
- W2913305810 cites W2737111284 @default.
- W2913305810 cites W2756843858 @default.
- W2913305810 cites W2757470567 @default.
- W2913305810 cites W2757923258 @default.
- W2913305810 cites W2766161142 @default.
- W2913305810 cites W2767025366 @default.
- W2913305810 cites W2778323315 @default.
- W2913305810 cites W2926339741 @default.
- W2913305810 doi "https://doi.org/10.5772/intechopen.78092" @default.
- W2913305810 hasPublicationYear "2019" @default.
- W2913305810 type Work @default.
- W2913305810 sameAs 2913305810 @default.
- W2913305810 citedByCount "1" @default.
- W2913305810 countsByYear W29133058102019 @default.
- W2913305810 crossrefType "book-chapter" @default.
- W2913305810 hasAuthorship W2913305810A5022880024 @default.
- W2913305810 hasAuthorship W2913305810A5029180656 @default.
- W2913305810 hasAuthorship W2913305810A5029509282 @default.
- W2913305810 hasAuthorship W2913305810A5065525353 @default.
- W2913305810 hasAuthorship W2913305810A5068702152 @default.
- W2913305810 hasBestOaLocation W29133058101 @default.
- W2913305810 hasConcept C104317684 @default.
- W2913305810 hasConcept C10854531 @default.