FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2913306983> ?p ?o ?g. }

• W2913306983 abstract "Background: Patients with high-risk coronary artery disease (CAD) may be difficult to identify. Methods: Using the PROMISE (Prospective Multicenter Imaging Study for Evaluation of Chest Pain) cohort randomized to coronary computed tomographic angiography (n=4589), 2 predictive models were developed for high-risk CAD, defined as left main stenosis (≥50% stenosis) or either (1) ≥50% stenosis [50] or (2) ≥70% stenosis [70] of 3 vessels or 2-vessel CAD involving the proximal left anterior descending artery. Pretest predictors were examined using stepwise logistic regression and assessed for discrimination and calibration. Results: High-risk CAD was identified in 6.6% [50] and 2.4% [70] of patients. Models developed to predict high-risk CAD discriminated well: [50], bias-corrected C statistic=0.73 (95% CI, 0.71−0.76); [70], bias-corrected C statistic=0.73 (95% CI, 0.68−0.77). Variables predictive of CAD in both models included family history of premature CAD, age, male sex, lower glomerular filtration rate, diabetes mellitus, elevated systolic blood pressure, and angina. Additionally, smoking history was predictive of [50] CAD and sedentary lifestyle of [70] CAD. Both models characterized high-risk CAD better than the Pooled Cohort Equation (area under the curve=0.70 and 0.71 for [50] and [70], respectively) and Diamond-Forrester risk scores (area under the curve=0.68 and 0.71, respectively). Both [50] and [70] CAD was associated with more frequent invasive interventions and adverse events than non-high-risk CAD (all P <0.0001). Conclusions: In contemporary practice, 2.4% to 6.6% of stable, symptomatic patients requiring noninvasive testing have high-risk CAD. A simple combination of pretest clinical variables improves prediction of high-risk CAD over traditional risk assessments. Clinical Trial Registration: URL: https://www.clinicaltrials.gov . Unique identifier: NCT01174550." @default.
• W2913306983 created "2019-02-21" @default.
• W2913306983 creator A5006133112 @default.
• W2913306983 creator A5007974856 @default.
• W2913306983 creator A5014777482 @default.
• W2913306983 creator A5023757786 @default.
• W2913306983 creator A5024590816 @default.
• W2913306983 creator A5025924520 @default.
• W2913306983 creator A5026357411 @default.
• W2913306983 creator A5033980948 @default.
• W2913306983 creator A5034130923 @default.
• W2913306983 creator A5057932551 @default.
• W2913306983 creator A5070050361 @default.
• W2913306983 creator A5079896280 @default.
• W2913306983 creator A5080161610 @default.
• W2913306983 creator A5080222829 @default.
• W2913306983 creator A5085820099 @default.
• W2913306983 date "2019-02-01" @default.
• W2913306983 modified "2023-10-15" @default.
• W2913306983 title "Predictive Model for High-Risk Coronary Artery Disease" @default.
• W2913306983 cites W141291462 @default.
• W2913306983 cites W177631884 @default.
• W2913306983 cites W178020778 @default.
• W2913306983 cites W1969839704 @default.
• W2913306983 cites W198055846 @default.
• W2913306983 cites W2009836882 @default.
• W2913306983 cites W2012192382 @default.
• W2913306983 cites W2024931228 @default.
• W2913306983 cites W2052209391 @default.
• W2913306983 cites W2067776095 @default.
• W2913306983 cites W2078233084 @default.
• W2913306983 cites W2087697674 @default.
• W2913306983 cites W2090087329 @default.
• W2913306983 cites W2097623458 @default.
• W2913306983 cites W2098674170 @default.
• W2913306983 cites W2103494211 @default.
• W2913306983 cites W2121504382 @default.
• W2913306983 cites W2126900802 @default.
• W2913306983 cites W2139948144 @default.
• W2913306983 cites W2140991303 @default.
• W2913306983 cites W2149755434 @default.
• W2913306983 cites W2153379234 @default.
• W2913306983 cites W2160133249 @default.
• W2913306983 cites W2166844418 @default.
• W2913306983 cites W2168536722 @default.
• W2913306983 cites W2171155303 @default.
• W2913306983 cites W2186191235 @default.
• W2913306983 cites W2225109326 @default.
• W2913306983 cites W2328176404 @default.
• W2913306983 cites W2334748255 @default.
• W2913306983 cites W2462699261 @default.
• W2913306983 cites W3001764054 @default.
• W2913306983 cites W3175417087 @default.
• W2913306983 cites W4300481656 @default.
• W2913306983 cites W4302867446 @default.
• W2913306983 doi "https://doi.org/10.1161/circimaging.118.007940" @default.
• W2913306983 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6368397" @default.
• W2913306983 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30712364" @default.
• W2913306983 hasPublicationYear "2019" @default.
• W2913306983 type Work @default.
• W2913306983 sameAs 2913306983 @default.
• W2913306983 citedByCount "22" @default.
• W2913306983 countsByYear W29133069832019 @default.
• W2913306983 countsByYear W29133069832020 @default.
• W2913306983 countsByYear W29133069832021 @default.
• W2913306983 countsByYear W29133069832022 @default.
• W2913306983 countsByYear W29133069832023 @default.
• W2913306983 crossrefType "journal-article" @default.
• W2913306983 hasAuthorship W2913306983A5006133112 @default.
• W2913306983 hasAuthorship W2913306983A5007974856 @default.
• W2913306983 hasAuthorship W2913306983A5014777482 @default.
• W2913306983 hasAuthorship W2913306983A5023757786 @default.
• W2913306983 hasAuthorship W2913306983A5024590816 @default.
• W2913306983 hasAuthorship W2913306983A5025924520 @default.
• W2913306983 hasAuthorship W2913306983A5026357411 @default.
• W2913306983 hasAuthorship W2913306983A5033980948 @default.
• W2913306983 hasAuthorship W2913306983A5034130923 @default.
• W2913306983 hasAuthorship W2913306983A5057932551 @default.
• W2913306983 hasAuthorship W2913306983A5070050361 @default.
• W2913306983 hasAuthorship W2913306983A5079896280 @default.
• W2913306983 hasAuthorship W2913306983A5080161610 @default.
• W2913306983 hasAuthorship W2913306983A5080222829 @default.
• W2913306983 hasAuthorship W2913306983A5085820099 @default.
• W2913306983 hasBestOaLocation W29133069831 @default.
• W2913306983 hasConcept C126322002 @default.
• W2913306983 hasConcept C127413603 @default.
• W2913306983 hasConcept C164705383 @default.
• W2913306983 hasConcept C194789388 @default.
• W2913306983 hasConcept C199639397 @default.
• W2913306983 hasConcept C2778213512 @default.
• W2913306983 hasConcept C2778704086 @default.
• W2913306983 hasConcept C2780007028 @default.
• W2913306983 hasConcept C71924100 @default.
• W2913306983 hasConcept C72563966 @default.
• W2913306983 hasConceptScore W2913306983C126322002 @default.
• W2913306983 hasConceptScore W2913306983C127413603 @default.
• W2913306983 hasConceptScore W2913306983C164705383 @default.
• W2913306983 hasConceptScore W2913306983C194789388 @default.
• W2913306983 hasConceptScore W2913306983C199639397 @default.
• W2913306983 hasConceptScore W2913306983C2778213512 @default.

• next