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- W2936703617 abstract "Herein, we developed a simple and rapid strategy to synthesize gold/silver bimetallic nanoclusters (Au/Ag NCs) with highly biochemical stability by a one-pot route. The Au/Ag NCs were obtained via a chemical reduction procedure in alkaline aqueous solution at 75 °C within only 20 min by employing bovine serum albumin (BSA) as both ligand and reductant. The as-obtained Au/Ag NCs displayed bright orange fluorescence with an emission peak located at 570 nm and temperature-dependent fluorescence property, which were utilized as fluorescent thermometer directly. More intriguingly, the Au/Ag NCs were very stable against various pH values, ions, biothiols, H2O2, fetal bovine serum (FBS), RPMI 1640 medium and amino acids. Taking advantage of the excellent biochemical stability, a ratiometric fluorescence biosensor, fluorescein-5-isothiocyanate (FITC)-Au/Ag NCs, was constructed for pH sensing based on the incorporation of FITC into the Au/Ag NCs. Furthermore, the ratiometric pH sensor was also successfully applied on the model of HeLa cells." @default.
- W2936703617 created "2019-04-25" @default.
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- W2936703617 date "2019-09-01" @default.
- W2936703617 modified "2023-10-18" @default.
- W2936703617 title "Rapid synthesis of Au/Ag bimetallic nanoclusters with highly biochemical stability and its applications for temperature and ratiometric pH sensing" @default.
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- W2936703617 doi "https://doi.org/10.1016/j.aca.2019.04.029" @default.
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