Matches in SemOpenAlex for { <https://semopenalex.org/work/W2950381989> ?p ?o ?g. }
- W2950381989 abstract "Campylobacter jejuni is the leading cause of bacterial gastroenteritis (campylobacteriosis) in humans worldwide, and the most frequent pathogen associated with Guillain-Barré syndrome (GBS) and Miller-Fisher syndrome (MFS). The study was designed in order to assess similarities between genomes of Campylobacter jejuni strains, isolated from children suffering from acute diarrhea in northeastern Poland, in comparison to C.jejuni genomes stored in public databases. The analysis involved phylogeny, resistome and virulome. In addition, the Campylobacter PubMLST database was used to estimate the prevalence of the analyzed C. jejuni sequence type (STs) in other countries.Campylobacter jejuni ST50, ST257 and ST51 represented 5.3%, 4.5% and 2.2% of the PubMLST records, respectively. Overall, strains representing the STs showed common resistance to tetracyclines (51.3%) and fluoroquinolones (31.8%), mediated through the tetO gene (98.2%) and point mutation (T86I) in the gyrA gene (100%). However, the latter was present in all our isolates. The major differences in virulence patterns concerned serotypes, lipooligosaccharide (LOS) classes and certain clinically relevant genes.Campylobacter jejuni ST50, ST51 and ST257 are among the top ten of STs isolated in Europe. WGS revealed diversity of serotypes and LOS classes in ST50 strains, that deserves further clinical and epidemiological investigations as it might be related to a risk of post-infectious neurological sequels such as Guillain-Barré syndrome. Additionally, the results implicate lower pathogenic potential and distinct transmission chains or reservoirs for C. jejuni ST51 isolates responsible for campylobacteriosis in northeastern Poland." @default.
- W2950381989 created "2019-06-27" @default.
- W2950381989 creator A5002237306 @default.
- W2950381989 creator A5011640988 @default.
- W2950381989 creator A5015422386 @default.
- W2950381989 creator A5032690853 @default.
- W2950381989 creator A5058359446 @default.
- W2950381989 creator A5062076988 @default.
- W2950381989 date "2019-06-19" @default.
- W2950381989 modified "2023-10-13" @default.
- W2950381989 title "Whole-genome comparative analysis of Campylobacter jejuni strains isolated from patients with diarrhea in northeastern Poland" @default.
- W2950381989 cites W128985141 @default.
- W2950381989 cites W1571121309 @default.
- W2950381989 cites W1837396250 @default.
- W2950381989 cites W1849301422 @default.
- W2950381989 cites W1937678612 @default.
- W2950381989 cites W1977184995 @default.
- W2950381989 cites W2004734915 @default.
- W2950381989 cites W2039114957 @default.
- W2950381989 cites W2059062594 @default.
- W2950381989 cites W2079617293 @default.
- W2950381989 cites W2096093282 @default.
- W2950381989 cites W2096682528 @default.
- W2950381989 cites W2099837668 @default.
- W2950381989 cites W2101378591 @default.
- W2950381989 cites W2114853012 @default.
- W2950381989 cites W2115157085 @default.
- W2950381989 cites W2116433671 @default.
- W2950381989 cites W2119217447 @default.
- W2950381989 cites W2120398179 @default.
- W2950381989 cites W2122673596 @default.
- W2950381989 cites W2127172172 @default.
- W2950381989 cites W2141052558 @default.
- W2950381989 cites W2158959437 @default.
- W2950381989 cites W2161183899 @default.
- W2950381989 cites W2163320297 @default.
- W2950381989 cites W2184405267 @default.
- W2950381989 cites W2185023692 @default.
- W2950381989 cites W2226073398 @default.
- W2950381989 cites W2311203695 @default.
- W2950381989 cites W2325746421 @default.
- W2950381989 cites W2527825180 @default.
- W2950381989 cites W2556002408 @default.
- W2950381989 cites W2593960886 @default.
- W2950381989 cites W2594810826 @default.
- W2950381989 cites W2604273485 @default.
- W2950381989 cites W2604297489 @default.
- W2950381989 cites W2625199325 @default.
- W2950381989 cites W2690832614 @default.
- W2950381989 cites W2730206157 @default.
- W2950381989 cites W2730252722 @default.
- W2950381989 cites W2739323458 @default.
- W2950381989 cites W2779019546 @default.
- W2950381989 cites W2787251114 @default.
- W2950381989 cites W2808425122 @default.
- W2950381989 cites W2811341007 @default.
- W2950381989 cites W2897904125 @default.
- W2950381989 cites W4211039149 @default.
- W2950381989 cites W4211054514 @default.
- W2950381989 cites W4233970575 @default.
- W2950381989 cites W4250985797 @default.
- W2950381989 doi "https://doi.org/10.1186/s13099-019-0313-x" @default.
- W2950381989 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6582539" @default.
- W2950381989 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31244901" @default.
- W2950381989 hasPublicationYear "2019" @default.
- W2950381989 type Work @default.
- W2950381989 sameAs 2950381989 @default.
- W2950381989 citedByCount "20" @default.
- W2950381989 countsByYear W29503819892020 @default.
- W2950381989 countsByYear W29503819892021 @default.
- W2950381989 countsByYear W29503819892022 @default.
- W2950381989 countsByYear W29503819892023 @default.
- W2950381989 crossrefType "journal-article" @default.
- W2950381989 hasAuthorship W2950381989A5002237306 @default.
- W2950381989 hasAuthorship W2950381989A5011640988 @default.
- W2950381989 hasAuthorship W2950381989A5015422386 @default.
- W2950381989 hasAuthorship W2950381989A5032690853 @default.
- W2950381989 hasAuthorship W2950381989A5058359446 @default.
- W2950381989 hasAuthorship W2950381989A5062076988 @default.
- W2950381989 hasBestOaLocation W29503819891 @default.
- W2950381989 hasConcept C10389963 @default.
- W2950381989 hasConcept C104317684 @default.
- W2950381989 hasConcept C135763542 @default.
- W2950381989 hasConcept C159047783 @default.
- W2950381989 hasConcept C199360897 @default.
- W2950381989 hasConcept C2776957140 @default.
- W2950381989 hasConcept C2777858656 @default.
- W2950381989 hasConcept C2779910956 @default.
- W2950381989 hasConcept C41008148 @default.
- W2950381989 hasConcept C523546767 @default.
- W2950381989 hasConcept C54355233 @default.
- W2950381989 hasConcept C77434933 @default.
- W2950381989 hasConcept C83852419 @default.
- W2950381989 hasConcept C86803240 @default.
- W2950381989 hasConcept C89423630 @default.
- W2950381989 hasConceptScore W2950381989C10389963 @default.
- W2950381989 hasConceptScore W2950381989C104317684 @default.
- W2950381989 hasConceptScore W2950381989C135763542 @default.
- W2950381989 hasConceptScore W2950381989C159047783 @default.
- W2950381989 hasConceptScore W2950381989C199360897 @default.