FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2953078619> ?p ?o ?g. }

• W2953078619 endingPage "86.e1" @default.
• W2953078619 startingPage "79" @default.
• W2953078619 abstract "To test whether youth with Down syndrome have aortic stiffness indices, as measured by pulse wave velocity (PWV), that differ from youth without Down syndrome and to compare reference-based age-adjusted (age-PWV-Z) and height-adjusted (Ht-PWV-Z) in youth with and without Down syndrome.Cross-sectional study of PWV in 129 adolescents with Down syndrome and 97 youth of comparable age, sex, race/ethnicity, and body mass index (BMI). PWV, age-PWV-Z, and Ht-PWV-Z were compared. Regression models were developed to test for associations with PWV.Youth with Down syndrome and controls were comparable in BMI-Z (1.4 [-1.5 to 2.8] vs 1.2 [-2.0 to 2.8], P = .57) but not Ht-Z (-2.3 [-4.7 to 0.8] vs 0.4 [-2.0 to 2.6], P < .0001). PWV (m/s, 5.0 [3.1-7.9] vs 5.0 [3.6-8.0], P = .5) and mean arterial pressure (MAP, mm Hg) (78 [61-102] vs 74 [64-97], P = .09) were not different between groups. In adjusted analyses confined to Down syndrome, PWV was associated only with BMI, but not age, black race, or MAP (R2 = 0.11). In contrast, BMI, age, black race, and MAP were all positively associated with and better explained PWV in controls (R2 = 0.50). PWV was not associated with height in youth with or without Down syndrome. Although age-PWV-Z was not different in Down syndrome (-0.36 [-2.93 to 3.49]) vs -0.15 [-2.32 to 3.22]), Ht-PWV-Z was greater in Down syndrome (0.32 [-2.28 to 4.07] vs -0.08 [-2.64 to 2.64], P = .002), and Ht-PWV-Z was greater than age-PWV-Z in Down syndrome (P < .0001).The lack of relationship of PWV, an independent predictor of adult cardiovascular events, with its traditional determinants including MAP suggests Down syndrome-specific phenomena may alter such relationships in this population. In youth with Down syndrome, Ht-adjusted PWV may overestimate aortic stiffness.Clinicaltrials.gov: NCT01821300." @default.
• W2953078619 created "2019-06-27" @default.
• W2953078619 creator A5012005703 @default.
• W2953078619 creator A5028132133 @default.
• W2953078619 creator A5038332096 @default.
• W2953078619 creator A5054892150 @default.
• W2953078619 creator A5058187980 @default.
• W2953078619 creator A5060693430 @default.
• W2953078619 creator A5069567812 @default.
• W2953078619 creator A5077690429 @default.
• W2953078619 creator A5078025451 @default.
• W2953078619 date "2019-09-01" @default.
• W2953078619 modified "2023-10-15" @default.
• W2953078619 title "Cross-Sectional Study of Arterial Stiffness in Adolescents with Down Syndrome" @default.
• W2953078619 cites W122349615 @default.
• W2953078619 cites W1484022435 @default.
• W2953078619 cites W1537679123 @default.
• W2953078619 cites W1790767033 @default.
• W2953078619 cites W1910322641 @default.
• W2953078619 cites W1966701557 @default.
• W2953078619 cites W1970066295 @default.
• W2953078619 cites W1980556102 @default.
• W2953078619 cites W1982444046 @default.
• W2953078619 cites W2005217112 @default.
• W2953078619 cites W2005371675 @default.
• W2953078619 cites W2008153217 @default.
• W2953078619 cites W2015758016 @default.
• W2953078619 cites W2024958543 @default.
• W2953078619 cites W2026412615 @default.
• W2953078619 cites W2036906728 @default.
• W2953078619 cites W2041131149 @default.
• W2953078619 cites W2049878269 @default.
• W2953078619 cites W2057962659 @default.
• W2953078619 cites W2063998910 @default.
• W2953078619 cites W2077356018 @default.
• W2953078619 cites W2084686498 @default.
• W2953078619 cites W2087254215 @default.
• W2953078619 cites W2091760531 @default.
• W2953078619 cites W2096252037 @default.
• W2953078619 cites W2097716578 @default.
• W2953078619 cites W2098071371 @default.
• W2953078619 cites W2098983190 @default.
• W2953078619 cites W2102015915 @default.
• W2953078619 cites W2108651744 @default.
• W2953078619 cites W2112943642 @default.
• W2953078619 cites W2113078769 @default.
• W2953078619 cites W2113541168 @default.
• W2953078619 cites W2113825239 @default.
• W2953078619 cites W2128880345 @default.
• W2953078619 cites W2134724351 @default.
• W2953078619 cites W2137363332 @default.
• W2953078619 cites W2143691602 @default.
• W2953078619 cites W2159403038 @default.
• W2953078619 cites W2160801689 @default.
• W2953078619 cites W2170390946 @default.
• W2953078619 cites W2172233351 @default.
• W2953078619 cites W2211617643 @default.
• W2953078619 cites W2212332614 @default.
• W2953078619 cites W2223832541 @default.
• W2953078619 cites W2257047321 @default.
• W2953078619 cites W2297046467 @default.
• W2953078619 cites W2312070181 @default.
• W2953078619 cites W2516599168 @default.
• W2953078619 cites W2567021276 @default.
• W2953078619 cites W2568465143 @default.
• W2953078619 cites W2604267604 @default.
• W2953078619 cites W2606057365 @default.
• W2953078619 cites W2616345961 @default.
• W2953078619 cites W2912807296 @default.
• W2953078619 cites W4251458288 @default.
• W2953078619 cites W82112906 @default.
• W2953078619 doi "https://doi.org/10.1016/j.jpeds.2019.04.059" @default.
• W2953078619 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6754250" @default.
• W2953078619 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31201031" @default.
• W2953078619 hasPublicationYear "2019" @default.
• W2953078619 type Work @default.
• W2953078619 sameAs 2953078619 @default.
• W2953078619 citedByCount "1" @default.
• W2953078619 countsByYear W29530786192023 @default.
• W2953078619 crossrefType "journal-article" @default.
• W2953078619 hasAuthorship W2953078619A5012005703 @default.
• W2953078619 hasAuthorship W2953078619A5028132133 @default.
• W2953078619 hasAuthorship W2953078619A5038332096 @default.
• W2953078619 hasAuthorship W2953078619A5054892150 @default.
• W2953078619 hasAuthorship W2953078619A5058187980 @default.
• W2953078619 hasAuthorship W2953078619A5060693430 @default.
• W2953078619 hasAuthorship W2953078619A5069567812 @default.
• W2953078619 hasAuthorship W2953078619A5077690429 @default.
• W2953078619 hasAuthorship W2953078619A5078025451 @default.
• W2953078619 hasBestOaLocation W29530786192 @default.
• W2953078619 hasConcept C126322002 @default.
• W2953078619 hasConcept C142052008 @default.
• W2953078619 hasConcept C142724271 @default.
• W2953078619 hasConcept C164705383 @default.
• W2953078619 hasConcept C2775850156 @default.
• W2953078619 hasConcept C2778319312 @default.
• W2953078619 hasConcept C2780221984 @default.
• W2953078619 hasConcept C71924100 @default.

• next