FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2962772094> ?p ?o ?g. }

• W2962772094 endingPage "1513" @default.
• W2962772094 startingPage "1505" @default.
• W2962772094 abstract "Abstract STUDY QUESTION Is the first-time redeemed prescription of antidepressants predicted by the level of infertility-related stress in women seeking ART treatment? SUMMARY ANSWER Infertility-related stress in the personal and marital domains and general physical stress reactions were significant predictors of a first redeemed prescription of antidepressants after ART treatment in this 10-year follow-up cohort study. WHAT IS KNOWN ALREADY The literature has found inconsistent findings regarding the association between infertility-related stress and later psychological adjustment in fertility patients. The association between infertility-related stress and later prescription of antidepressants had never been explored in long-term cohort studies. STUDY DESIGN, SIZE, DURATION All women (n = 1169) who participated in the Copenhagen Cohort Multi-centre Psychosocial Infertility (COMPI) cohort study in the year 2000 (questionnaire data) were linked with the register-based Danish National ART-Couple (DANAC) I cohort, which includes women and their partners having received ART treatment from 1 January 1994 to 30 September 2009. The study population were among other national health and sociodemographic registers further linked with the Danish National Prescription Registry. PARTICIPANTS/MATERIALS, SETTING, METHODS Women initiating ART treatment were followed until they had redeemed the first prescription of antidepressants or until 31 December 2009. Logistic regression analyses were conducted to test the association between general physical stress reactions and infertility-related stress in the personal, marital and social domains, respectively, and a future redeemed prescription of antidepressants. Age, education level, marital status, number of fertility treatments prior to study inclusion and female infertility diagnosis were included as covariates in the adjusted analyses. Further, the analysis was stratified according to childbirth or no childbirth during follow-up. MAIN RESULTS AND THE ROLE OF CHANCE The final sample consisted of 1009 women with a mean age of 31.8 years. At study inclusion, women had tried to conceive for an average of 3.45 years. At 10-year follow-up, a total of 13.7% of women had a first redeemed prescription of antidepressant medication. The adjusted odds ratio (OR) showed that high general physical stress predicted the later prescription of antidepressants (adjusted (adj) OR = 2.85, 95% confidence interval (CI) 1.96–4.16). Regarding infertility-related stress domains, high personal stress (adj OR = 2.14, 95% CI 1.46–3.13) and high marital stress (adj OR = 1.80, 95% CI 1.23–2.64) were significantly associated with the later prescription of antidepressants. Social stress was not significantly associated with the future redeemed prescription of antidepressants (adj OR = 1.10, 95% CI 0.76–1.61). Among women not having achieved childbirth during follow-up, the risk of a first-time prescription of antidepressants associated with infertility-specific stress was higher compared to the risk among women having childbirth during follow-up. LIMITATIONS, REASONS FOR CAUTION This study did not account for potential mediating factors, such as negative life events, which could be associated with the prescription of antidepressants. Second, we are not able to know if these women had sought psychological support during follow-up. Additionally, antidepressants might be prescribed for other health conditions than depressive disorders. WIDER IMPLICATIONS OF THE FINDINGS Our results suggest that women presenting high infertility-related stress in the personal and marital domains were at higher risk of redeemed first-time prescription of antidepressants after ART, independently of having delivered a child or not after initiation of ART treatment. Women would benefit from an initial screening specifically for high infertility-related stress. The COMPI Fertility Problem Stress Scales can be used by clinical staff in order to identify women in need of psychological support before starting ART treatments. STUDY FUNDING/COMPETING INTEREST(S) This study was supported by the Portuguese Foundation for Science and Technology (FCT) under an individual doctoral grant attributed to the first author (SFRH/BD/103234/2014). The establishment of the DANAC I cohort was funded by Rosa Ebba Hansen’s Fund. The COMPI Infertility Cohort project was supported by The Danish Health Insurance Fund (J.nr. 11/097–97), the Else and Mogens Wedell-Wedellsborgs Fund, the manager E. Danielsens and Wife’s Fund, the merchant L.F. Foghts Fund, the Jacob Madsen and Wife Olga Madsens Fund. The authors have no conflicts of interest. TRIAL REGISTRATION NUMBER NA" @default.
• W2962772094 created "2019-07-30" @default.
• W2962772094 creator A5002050845 @default.
• W2962772094 creator A5004004580 @default.
• W2962772094 creator A5037248554 @default.
• W2962772094 creator A5055060490 @default.
• W2962772094 creator A5060158710 @default.
• W2962772094 creator A5075845482 @default.
• W2962772094 date "2019-07-24" @default.
• W2962772094 modified "2023-09-23" @default.
• W2962772094 title "Infertility-related stress and the risk of antidepressants prescription in women: a 10-year register study" @default.
• W2962772094 cites W1218374853 @default.
• W2962772094 cites W1754375904 @default.
• W2962772094 cites W1898254775 @default.
• W2962772094 cites W1940844648 @default.
• W2962772094 cites W1987008817 @default.
• W2962772094 cites W1997990909 @default.
• W2962772094 cites W2002508863 @default.
• W2962772094 cites W2002516694 @default.
• W2962772094 cites W2009374347 @default.
• W2962772094 cites W2016057960 @default.
• W2962772094 cites W2022835494 @default.
• W2962772094 cites W2045727744 @default.
• W2962772094 cites W2056554058 @default.
• W2962772094 cites W2058473061 @default.
• W2962772094 cites W2071290380 @default.
• W2962772094 cites W2100217710 @default.
• W2962772094 cites W2101258836 @default.
• W2962772094 cites W2109129651 @default.
• W2962772094 cites W2121200584 @default.
• W2962772094 cites W2124439404 @default.
• W2962772094 cites W2129603642 @default.
• W2962772094 cites W2130943232 @default.
• W2962772094 cites W2131940349 @default.
• W2962772094 cites W2137347968 @default.
• W2962772094 cites W2140584348 @default.
• W2962772094 cites W2142284850 @default.
• W2962772094 cites W2142749836 @default.
• W2962772094 cites W2145986098 @default.
• W2962772094 cites W2146046641 @default.
• W2962772094 cites W2150740382 @default.
• W2962772094 cites W2157583335 @default.
• W2962772094 cites W2169624100 @default.
• W2962772094 cites W2171652143 @default.
• W2962772094 cites W2272396419 @default.
• W2962772094 cites W2283025062 @default.
• W2962772094 cites W2295102288 @default.
• W2962772094 cites W2397340449 @default.
• W2962772094 cites W2555531852 @default.
• W2962772094 cites W2567423128 @default.
• W2962772094 cites W2589554180 @default.
• W2962772094 cites W2591265670 @default.
• W2962772094 cites W2791428642 @default.
• W2962772094 cites W2803748719 @default.
• W2962772094 cites W2804566355 @default.
• W2962772094 cites W4240776723 @default.
• W2962772094 doi "https://doi.org/10.1093/humrep/dez110" @default.
• W2962772094 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31339996" @default.
• W2962772094 hasPublicationYear "2019" @default.
• W2962772094 type Work @default.
• W2962772094 sameAs 2962772094 @default.
• W2962772094 citedByCount "13" @default.
• W2962772094 countsByYear W29627720942020 @default.
• W2962772094 countsByYear W29627720942021 @default.
• W2962772094 countsByYear W29627720942022 @default.
• W2962772094 countsByYear W29627720942023 @default.
• W2962772094 crossrefType "journal-article" @default.
• W2962772094 hasAuthorship W2962772094A5002050845 @default.
• W2962772094 hasAuthorship W2962772094A5004004580 @default.
• W2962772094 hasAuthorship W2962772094A5037248554 @default.
• W2962772094 hasAuthorship W2962772094A5055060490 @default.
• W2962772094 hasAuthorship W2962772094A5060158710 @default.
• W2962772094 hasAuthorship W2962772094A5075845482 @default.
• W2962772094 hasConcept C118552586 @default.
• W2962772094 hasConcept C126322002 @default.
• W2962772094 hasConcept C144024400 @default.
• W2962772094 hasConcept C149923435 @default.
• W2962772094 hasConcept C150966472 @default.
• W2962772094 hasConcept C201903717 @default.
• W2962772094 hasConcept C2426938 @default.
• W2962772094 hasConcept C2777688143 @default.
• W2962772094 hasConcept C2779234561 @default.
• W2962772094 hasConcept C2781354955 @default.
• W2962772094 hasConcept C2908647359 @default.
• W2962772094 hasConcept C518429986 @default.
• W2962772094 hasConcept C54355233 @default.
• W2962772094 hasConcept C71924100 @default.
• W2962772094 hasConcept C72563966 @default.
• W2962772094 hasConcept C86803240 @default.
• W2962772094 hasConcept C98274493 @default.
• W2962772094 hasConcept C99454951 @default.
• W2962772094 hasConceptScore W2962772094C118552586 @default.
• W2962772094 hasConceptScore W2962772094C126322002 @default.
• W2962772094 hasConceptScore W2962772094C144024400 @default.
• W2962772094 hasConceptScore W2962772094C149923435 @default.
• W2962772094 hasConceptScore W2962772094C150966472 @default.
• W2962772094 hasConceptScore W2962772094C201903717 @default.
• W2962772094 hasConceptScore W2962772094C2426938 @default.

• next