Matches in SemOpenAlex for { <https://semopenalex.org/work/W3046878312> ?p ?o ?g. }
- W3046878312 endingPage "12001" @default.
- W3046878312 startingPage "11994" @default.
- W3046878312 abstract "Most studies of ultrasensitive diagnosis of biomolecules from liquid specimens are limited by problems during sample preparation steps, including enrichment and isolation of biomolecules. Here we report a novel platform combining bis(sulfosuccinimidyl)suberate (BS3) and helix-shaped microchannels (BSH) to change the sample preparation paradigm. This BSH system is composed of BS3 for pathogen enrichment and nucleic acid isolation by electrostatic and covalent interaction, and helix-shaped microchannels to minimize sample loss and remove bubbles in large liquid specimens without pH change. The system detected Mycobacterium tuberculosis following enrichment and isolation of 10 mL of liquefied sputum from 11 patients with tuberculosis. Moreover, the system identified KRAS mutations following cell-free DNA isolation of blood plasma from 10 patients with colorectal cancer. This system allows ultrasensitive diagnosis in various disease applications with large volumes of liquid samples." @default.
- W3046878312 created "2020-08-07" @default.
- W3046878312 creator A5010721594 @default.
- W3046878312 creator A5030586485 @default.
- W3046878312 creator A5044640531 @default.
- W3046878312 creator A5066703570 @default.
- W3046878312 creator A5067286446 @default.
- W3046878312 creator A5074171124 @default.
- W3046878312 date "2020-07-30" @default.
- W3046878312 modified "2023-10-09" @default.
- W3046878312 title "Bis(sulfosuccinimidyl)suberate-Based Helix-Shaped Microchannels as Enhancers of Biomolecule Isolation from Liquid Biopsies" @default.
- W3046878312 cites W1827451378 @default.
- W3046878312 cites W1963853602 @default.
- W3046878312 cites W2022326530 @default.
- W3046878312 cites W2027735722 @default.
- W3046878312 cites W2089231026 @default.
- W3046878312 cites W2135924719 @default.
- W3046878312 cites W2150575159 @default.
- W3046878312 cites W2159036879 @default.
- W3046878312 cites W2346880656 @default.
- W3046878312 cites W2470646526 @default.
- W3046878312 cites W2589694509 @default.
- W3046878312 cites W2590954301 @default.
- W3046878312 cites W2593435710 @default.
- W3046878312 cites W2603459612 @default.
- W3046878312 cites W2606832963 @default.
- W3046878312 cites W2650816283 @default.
- W3046878312 cites W2783537195 @default.
- W3046878312 cites W2794415758 @default.
- W3046878312 cites W2795841352 @default.
- W3046878312 cites W2796237562 @default.
- W3046878312 cites W2806774249 @default.
- W3046878312 cites W2886043109 @default.
- W3046878312 cites W2918329148 @default.
- W3046878312 cites W2947061021 @default.
- W3046878312 cites W2994594505 @default.
- W3046878312 cites W3004280078 @default.
- W3046878312 cites W3012568633 @default.
- W3046878312 cites W4234746319 @default.
- W3046878312 cites W4376848401 @default.
- W3046878312 doi "https://doi.org/10.1021/acs.analchem.0c02503" @default.
- W3046878312 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32867489" @default.
- W3046878312 hasPublicationYear "2020" @default.
- W3046878312 type Work @default.
- W3046878312 sameAs 3046878312 @default.
- W3046878312 citedByCount "7" @default.
- W3046878312 countsByYear W30468783122022 @default.
- W3046878312 countsByYear W30468783122023 @default.
- W3046878312 crossrefType "journal-article" @default.
- W3046878312 hasAuthorship W3046878312A5010721594 @default.
- W3046878312 hasAuthorship W3046878312A5030586485 @default.
- W3046878312 hasAuthorship W3046878312A5044640531 @default.
- W3046878312 hasAuthorship W3046878312A5066703570 @default.
- W3046878312 hasAuthorship W3046878312A5067286446 @default.
- W3046878312 hasAuthorship W3046878312A5074171124 @default.
- W3046878312 hasConcept C104317684 @default.
- W3046878312 hasConcept C111936080 @default.
- W3046878312 hasConcept C121608353 @default.
- W3046878312 hasConcept C12554922 @default.
- W3046878312 hasConcept C126322002 @default.
- W3046878312 hasConcept C142724271 @default.
- W3046878312 hasConcept C150194340 @default.
- W3046878312 hasConcept C185592680 @default.
- W3046878312 hasConcept C24107716 @default.
- W3046878312 hasConcept C2775941552 @default.
- W3046878312 hasConcept C2777975735 @default.
- W3046878312 hasConcept C2779529041 @default.
- W3046878312 hasConcept C2781069245 @default.
- W3046878312 hasConcept C43617362 @default.
- W3046878312 hasConcept C49853544 @default.
- W3046878312 hasConcept C552990157 @default.
- W3046878312 hasConcept C55493867 @default.
- W3046878312 hasConcept C71924100 @default.
- W3046878312 hasConcept C86803240 @default.
- W3046878312 hasConcept C89423630 @default.
- W3046878312 hasConceptScore W3046878312C104317684 @default.
- W3046878312 hasConceptScore W3046878312C111936080 @default.
- W3046878312 hasConceptScore W3046878312C121608353 @default.
- W3046878312 hasConceptScore W3046878312C12554922 @default.
- W3046878312 hasConceptScore W3046878312C126322002 @default.
- W3046878312 hasConceptScore W3046878312C142724271 @default.
- W3046878312 hasConceptScore W3046878312C150194340 @default.
- W3046878312 hasConceptScore W3046878312C185592680 @default.
- W3046878312 hasConceptScore W3046878312C24107716 @default.
- W3046878312 hasConceptScore W3046878312C2775941552 @default.
- W3046878312 hasConceptScore W3046878312C2777975735 @default.
- W3046878312 hasConceptScore W3046878312C2779529041 @default.
- W3046878312 hasConceptScore W3046878312C2781069245 @default.
- W3046878312 hasConceptScore W3046878312C43617362 @default.
- W3046878312 hasConceptScore W3046878312C49853544 @default.
- W3046878312 hasConceptScore W3046878312C552990157 @default.
- W3046878312 hasConceptScore W3046878312C55493867 @default.
- W3046878312 hasConceptScore W3046878312C71924100 @default.
- W3046878312 hasConceptScore W3046878312C86803240 @default.
- W3046878312 hasConceptScore W3046878312C89423630 @default.
- W3046878312 hasFunder F4320322034 @default.
- W3046878312 hasFunder F4320322120 @default.
- W3046878312 hasIssue "17" @default.