Matches in SemOpenAlex for { <https://semopenalex.org/work/W307753342> ?p ?o ?g. }
- W307753342 endingPage "177" @default.
- W307753342 startingPage "171" @default.
- W307753342 abstract "This chapter discusses the effects of nutritional deficiency on systemic and local immunity and implication for gastrointestinal disease. The immunosuppressive effects of undernutrition, together with observations that infection is of greater severity, lasts longer and recurs more frequently in malnourished children, is well documented. Among the nutritional deficiencies, energy, protein, iron, folic acid, vitamin A, pyridoxine and zinc, both individually and collectively, have been examined in depth. Profound thymic atrophy was identified as one of the striking histopathological features of severe malnutrition more than 50 years ago. The thymus is small with ill-defined demarcations between the cortex and the medulla. There are fewer than normal lymphoid cells, and Hassal corpuscles are crowded, dilated, and degenerate and occasionally, even calcified. There is cellular depletion with involution of thymus-dependent areas in the spleen and lymph nodes. These morphological alterations are reflected in reduced activity of serum thymic factor. Defects in the ability of neutrophils to respond chemotactically are implied by the presence of mucocutaneous lesions and superficial necrotizing lesions with pyogenic bacteria during protein-energy malnutrition." @default.
- W307753342 created "2016-06-24" @default.
- W307753342 creator A5078128297 @default.
- W307753342 creator A5082806421 @default.
- W307753342 date "1986-01-01" @default.
- W307753342 modified "2023-09-26" @default.
- W307753342 title "The effects of nutritional deficiency on systemic and local immunity: implication for gastrointestinal disease" @default.
- W307753342 cites W1583266974 @default.
- W307753342 cites W1789002579 @default.
- W307753342 cites W184060769 @default.
- W307753342 cites W1870525143 @default.
- W307753342 cites W187256664 @default.
- W307753342 cites W1948634989 @default.
- W307753342 cites W1949384144 @default.
- W307753342 cites W1950619755 @default.
- W307753342 cites W1971581697 @default.
- W307753342 cites W198370896 @default.
- W307753342 cites W1984903062 @default.
- W307753342 cites W2009733710 @default.
- W307753342 cites W2027219033 @default.
- W307753342 cites W2037547948 @default.
- W307753342 cites W2061863401 @default.
- W307753342 cites W2073925603 @default.
- W307753342 cites W2101046905 @default.
- W307753342 cites W2122722265 @default.
- W307753342 cites W2122846775 @default.
- W307753342 cites W2123170785 @default.
- W307753342 cites W2146695572 @default.
- W307753342 cites W2166809887 @default.
- W307753342 cites W2412491845 @default.
- W307753342 cites W2423630202 @default.
- W307753342 cites W2999646561 @default.
- W307753342 cites W997847596 @default.
- W307753342 doi "https://doi.org/10.1016/b978-0-407-00401-6.50032-4" @default.
- W307753342 hasPublicationYear "1986" @default.
- W307753342 type Work @default.
- W307753342 sameAs 307753342 @default.
- W307753342 citedByCount "1" @default.
- W307753342 crossrefType "book-chapter" @default.
- W307753342 hasAuthorship W307753342A5078128297 @default.
- W307753342 hasAuthorship W307753342A5082806421 @default.
- W307753342 hasConcept C142724271 @default.
- W307753342 hasConcept C169760540 @default.
- W307753342 hasConcept C181152851 @default.
- W307753342 hasConcept C186720457 @default.
- W307753342 hasConcept C203014093 @default.
- W307753342 hasConcept C2776090121 @default.
- W307753342 hasConcept C2777314012 @default.
- W307753342 hasConcept C2779134260 @default.
- W307753342 hasConcept C2779341262 @default.
- W307753342 hasConcept C2779613291 @default.
- W307753342 hasConcept C2779720271 @default.
- W307753342 hasConcept C2780931953 @default.
- W307753342 hasConcept C2781172350 @default.
- W307753342 hasConcept C2781184604 @default.
- W307753342 hasConcept C2781409172 @default.
- W307753342 hasConcept C551997983 @default.
- W307753342 hasConcept C71924100 @default.
- W307753342 hasConcept C86803240 @default.
- W307753342 hasConcept C8891405 @default.
- W307753342 hasConceptScore W307753342C142724271 @default.
- W307753342 hasConceptScore W307753342C169760540 @default.
- W307753342 hasConceptScore W307753342C181152851 @default.
- W307753342 hasConceptScore W307753342C186720457 @default.
- W307753342 hasConceptScore W307753342C203014093 @default.
- W307753342 hasConceptScore W307753342C2776090121 @default.
- W307753342 hasConceptScore W307753342C2777314012 @default.
- W307753342 hasConceptScore W307753342C2779134260 @default.
- W307753342 hasConceptScore W307753342C2779341262 @default.
- W307753342 hasConceptScore W307753342C2779613291 @default.
- W307753342 hasConceptScore W307753342C2779720271 @default.
- W307753342 hasConceptScore W307753342C2780931953 @default.
- W307753342 hasConceptScore W307753342C2781172350 @default.
- W307753342 hasConceptScore W307753342C2781184604 @default.
- W307753342 hasConceptScore W307753342C2781409172 @default.
- W307753342 hasConceptScore W307753342C551997983 @default.
- W307753342 hasConceptScore W307753342C71924100 @default.
- W307753342 hasConceptScore W307753342C86803240 @default.
- W307753342 hasConceptScore W307753342C8891405 @default.
- W307753342 hasLocation W3077533421 @default.
- W307753342 hasOpenAccess W307753342 @default.
- W307753342 hasPrimaryLocation W3077533421 @default.
- W307753342 hasRelatedWork W109589233 @default.
- W307753342 hasRelatedWork W14993635 @default.
- W307753342 hasRelatedWork W1967572352 @default.
- W307753342 hasRelatedWork W1978502231 @default.
- W307753342 hasRelatedWork W2005803857 @default.
- W307753342 hasRelatedWork W2032503001 @default.
- W307753342 hasRelatedWork W2043357396 @default.
- W307753342 hasRelatedWork W2076896406 @default.
- W307753342 hasRelatedWork W2123450707 @default.
- W307753342 hasRelatedWork W2139062456 @default.
- W307753342 hasRelatedWork W2158934985 @default.
- W307753342 hasRelatedWork W2162144888 @default.
- W307753342 hasRelatedWork W2167399127 @default.
- W307753342 hasRelatedWork W2359249166 @default.
- W307753342 hasRelatedWork W2397677302 @default.
- W307753342 hasRelatedWork W2405303987 @default.