FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3090278314> ?p ?o ?g. }

• W3090278314 endingPage "6154" @default.
• W3090278314 startingPage "6154" @default.
• W3090278314 abstract "Dengue is one of the most rapidly spreading mosquito-borne viral diseases in the world. Differential diagnosis is a crucial step for the management of the disease and its epidemiology. Point-of-care testing of blood-borne dengue biomarkers provides an advantageous approach in many health care settings, and the ability to follow more than one biomarker at once could significantly improve the management of the disease. Bead-based multiplex technologies (suspension array) can measure multiple biomarker targets simultaneously by using recognition molecules immobilized on microsphere beads. The overarching objective of our work is to develop a portable detection device for the simultaneous measurement of multiple biomarkers important in dengue diagnosis, monitoring and treatment. Here, we present a bead-based assay for the detection of one of the four serotypes of dengue virus non-structural protein (DENV-NS1) as well as its cognate human IgG. In this system, the fluorescent microspheres containing the classification fluorophore and detection fluorophore are imaged through a microfluidic chip using an infinity-corrected microscope system. Calibration curves were plotted for median fluorescence intensity against known concentrations of DENV-NS1 protein and anti-NS1 human IgG. The limit of quantitation was 7.8 ng/mL and 15.6 ng/mL, respectively. The results of this study demonstrate the feasibility of the multiplex detection of dengue biomarkers and present its analytical performance parameters. The proposed imaging device holds potential for point-of-care testing of biomarkers on a highly portable system, and it may facilitate the diagnosis and prevention of dengue as well as other infectious diseases." @default.
• W3090278314 created "2020-10-08" @default.
• W3090278314 creator A5001867131 @default.
• W3090278314 creator A5012582312 @default.
• W3090278314 creator A5015697237 @default.
• W3090278314 creator A5026608291 @default.
• W3090278314 creator A5029364574 @default.
• W3090278314 creator A5038482388 @default.
• W3090278314 creator A5042142814 @default.
• W3090278314 creator A5044259899 @default.
• W3090278314 creator A5046701452 @default.
• W3090278314 creator A5048670457 @default.
• W3090278314 creator A5082335614 @default.
• W3090278314 creator A5089685445 @default.
• W3090278314 date "2020-10-07" @default.
• W3090278314 modified "2023-09-25" @default.
• W3090278314 title "Bead-based multiplex detection of dengue biomarkers in a portable imaging device" @default.
• W3090278314 cites W1792975234 @default.
• W3090278314 cites W1975379771 @default.
• W3090278314 cites W1988906448 @default.
• W3090278314 cites W2017350973 @default.
• W3090278314 cites W2032386764 @default.
• W3090278314 cites W2079103525 @default.
• W3090278314 cites W2096816967 @default.
• W3090278314 cites W2097875868 @default.
• W3090278314 cites W2119817288 @default.
• W3090278314 cites W2122716492 @default.
• W3090278314 cites W2129060396 @default.
• W3090278314 cites W2145172626 @default.
• W3090278314 cites W2146006596 @default.
• W3090278314 cites W2166388790 @default.
• W3090278314 cites W2170619342 @default.
• W3090278314 cites W2546215193 @default.
• W3090278314 cites W2603968540 @default.
• W3090278314 cites W2608617863 @default.
• W3090278314 cites W2617939011 @default.
• W3090278314 cites W2742686428 @default.
• W3090278314 cites W2755224396 @default.
• W3090278314 cites W2760695432 @default.
• W3090278314 cites W2767961623 @default.
• W3090278314 cites W2782110415 @default.
• W3090278314 cites W2789834086 @default.
• W3090278314 cites W2821586886 @default.
• W3090278314 cites W2886385809 @default.
• W3090278314 cites W2909146242 @default.
• W3090278314 cites W2909998782 @default.
• W3090278314 cites W2911451966 @default.
• W3090278314 cites W2912891525 @default.
• W3090278314 cites W2925199598 @default.
• W3090278314 cites W2953720735 @default.
• W3090278314 cites W3100115611 @default.
• W3090278314 doi "https://doi.org/10.1364/boe.403803" @default.
• W3090278314 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7687939" @default.
• W3090278314 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33282481" @default.
• W3090278314 hasPublicationYear "2020" @default.
• W3090278314 type Work @default.
• W3090278314 sameAs 3090278314 @default.
• W3090278314 citedByCount "5" @default.
• W3090278314 countsByYear W30902783142021 @default.
• W3090278314 countsByYear W30902783142022 @default.
• W3090278314 countsByYear W30902783142023 @default.
• W3090278314 crossrefType "journal-article" @default.
• W3090278314 hasAuthorship W3090278314A5001867131 @default.
• W3090278314 hasAuthorship W3090278314A5012582312 @default.
• W3090278314 hasAuthorship W3090278314A5015697237 @default.
• W3090278314 hasAuthorship W3090278314A5026608291 @default.
• W3090278314 hasAuthorship W3090278314A5029364574 @default.
• W3090278314 hasAuthorship W3090278314A5038482388 @default.
• W3090278314 hasAuthorship W3090278314A5042142814 @default.
• W3090278314 hasAuthorship W3090278314A5044259899 @default.
• W3090278314 hasAuthorship W3090278314A5046701452 @default.
• W3090278314 hasAuthorship W3090278314A5048670457 @default.
• W3090278314 hasAuthorship W3090278314A5082335614 @default.
• W3090278314 hasAuthorship W3090278314A5089685445 @default.
• W3090278314 hasBestOaLocation W30902783141 @default.
• W3090278314 hasConcept C119128265 @default.
• W3090278314 hasConcept C120665830 @default.
• W3090278314 hasConcept C121332964 @default.
• W3090278314 hasConcept C136229726 @default.
• W3090278314 hasConcept C142724271 @default.
• W3090278314 hasConcept C159047783 @default.
• W3090278314 hasConcept C185592680 @default.
• W3090278314 hasConcept C2778617687 @default.
• W3090278314 hasConcept C2779635636 @default.
• W3090278314 hasConcept C2781188995 @default.
• W3090278314 hasConcept C2781197716 @default.
• W3090278314 hasConcept C43617362 @default.
• W3090278314 hasConcept C51915194 @default.
• W3090278314 hasConcept C533803919 @default.
• W3090278314 hasConcept C55493867 @default.
• W3090278314 hasConcept C60644358 @default.
• W3090278314 hasConcept C64841741 @default.
• W3090278314 hasConcept C71924100 @default.
• W3090278314 hasConcept C86803240 @default.
• W3090278314 hasConcept C91881484 @default.
• W3090278314 hasConceptScore W3090278314C119128265 @default.
• W3090278314 hasConceptScore W3090278314C120665830 @default.
• W3090278314 hasConceptScore W3090278314C121332964 @default.

• next