FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3100102575> ?p ?o ?g. }

• W3100102575 endingPage "284" @default.
• W3100102575 startingPage "284" @default.
• W3100102575 abstract "In Schizosaccharomyces pombe, the spore wall confers strong resistance against external stress. During meiosis II, the double-layered intracellular forespore membrane (FSM) forms de novo and encapsulates the nucleus. Eventually, the inner FSM layer becomes the plasma membrane of the spore, while the outer layer breaks down. However, the molecular mechanism and biological significance of this membrane breakdown remain unknown. Here, by genetic investigation of an S. pombe mutant (E22) with normal prespore formation but abnormal spores, we showed that Meu5, an RNA-binding protein known to bind to and stabilize more than 80 transcripts, is involved in this process. We confirmed that the E22 mutant does not produce Meu5 protein, while overexpression of meu5+ in E22 restores the sporulation defect. Furthermore, electron microscopy revealed that the outer membrane of the FSM persisted in meu5∆ spores. Investigation of the target genes of meu5+ showed that a mutant of cyc1+ encoding cytochrome c also showed a severe defect in outer FSM breakdown. Lastly, we determined that outer FSM breakdown occurs coincident with or after formation of the outermost Isp3 layer of the spore wall. Collectively, our data provide novel insights into the molecular mechanism of spore formation." @default.
• W3100102575 created "2020-11-23" @default.
• W3100102575 creator A5001600788 @default.
• W3100102575 creator A5009248386 @default.
• W3100102575 creator A5024832790 @default.
• W3100102575 creator A5047326052 @default.
• W3100102575 creator A5082163527 @default.
• W3100102575 creator A5084655786 @default.
• W3100102575 creator A5086909608 @default.
• W3100102575 creator A5090388479 @default.
• W3100102575 date "2020-11-13" @default.
• W3100102575 modified "2023-09-26" @default.
• W3100102575 title "The Fission Yeast RNA-Binding Protein Meu5 Is Involved in Outer Forespore Membrane Breakdown during Spore Formation" @default.
• W3100102575 cites W109358480 @default.
• W3100102575 cites W1485797794 @default.
• W3100102575 cites W1507436219 @default.
• W3100102575 cites W1583351416 @default.
• W3100102575 cites W1599776991 @default.
• W3100102575 cites W1753492468 @default.
• W3100102575 cites W1809987813 @default.
• W3100102575 cites W1882496296 @default.
• W3100102575 cites W1917693299 @default.
• W3100102575 cites W1965473680 @default.
• W3100102575 cites W1970426445 @default.
• W3100102575 cites W1973067220 @default.
• W3100102575 cites W1974062319 @default.
• W3100102575 cites W1983169741 @default.
• W3100102575 cites W1983703794 @default.
• W3100102575 cites W1994136852 @default.
• W3100102575 cites W2007665576 @default.
• W3100102575 cites W2010228033 @default.
• W3100102575 cites W2033049942 @default.
• W3100102575 cites W2039524986 @default.
• W3100102575 cites W2044185614 @default.
• W3100102575 cites W2053153067 @default.
• W3100102575 cites W2053650278 @default.
• W3100102575 cites W2057427296 @default.
• W3100102575 cites W2057580822 @default.
• W3100102575 cites W2058268810 @default.
• W3100102575 cites W2069297824 @default.
• W3100102575 cites W2070172579 @default.
• W3100102575 cites W2075679162 @default.
• W3100102575 cites W2088744795 @default.
• W3100102575 cites W2097919448 @default.
• W3100102575 cites W2101477327 @default.
• W3100102575 cites W2109635944 @default.
• W3100102575 cites W2125885481 @default.
• W3100102575 cites W2131088281 @default.
• W3100102575 cites W2150470031 @default.
• W3100102575 cites W2154066368 @default.
• W3100102575 cites W2169645403 @default.
• W3100102575 cites W2236011578 @default.
• W3100102575 cites W2520056299 @default.
• W3100102575 cites W2777285287 @default.
• W3100102575 cites W2983308964 @default.
• W3100102575 cites W329360208 @default.
• W3100102575 doi "https://doi.org/10.3390/jof6040284" @default.
• W3100102575 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7712723" @default.
• W3100102575 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33202882" @default.
• W3100102575 hasPublicationYear "2020" @default.
• W3100102575 type Work @default.
• W3100102575 sameAs 3100102575 @default.
• W3100102575 citedByCount "4" @default.
• W3100102575 countsByYear W31001025752021 @default.
• W3100102575 countsByYear W31001025752022 @default.
• W3100102575 crossrefType "journal-article" @default.
• W3100102575 hasAuthorship W3100102575A5001600788 @default.
• W3100102575 hasAuthorship W3100102575A5009248386 @default.
• W3100102575 hasAuthorship W3100102575A5024832790 @default.
• W3100102575 hasAuthorship W3100102575A5047326052 @default.
• W3100102575 hasAuthorship W3100102575A5082163527 @default.
• W3100102575 hasAuthorship W3100102575A5084655786 @default.
• W3100102575 hasAuthorship W3100102575A5086909608 @default.
• W3100102575 hasAuthorship W3100102575A5090388479 @default.
• W3100102575 hasBestOaLocation W31001025751 @default.
• W3100102575 hasConcept C104317684 @default.
• W3100102575 hasConcept C12554922 @default.
• W3100102575 hasConcept C143065580 @default.
• W3100102575 hasConcept C146587185 @default.
• W3100102575 hasConcept C174618031 @default.
• W3100102575 hasConcept C2776519988 @default.
• W3100102575 hasConcept C2777896290 @default.
• W3100102575 hasConcept C2779429346 @default.
• W3100102575 hasConcept C2780723820 @default.
• W3100102575 hasConcept C41625074 @default.
• W3100102575 hasConcept C547475151 @default.
• W3100102575 hasConcept C55493867 @default.
• W3100102575 hasConcept C65871279 @default.
• W3100102575 hasConcept C67705224 @default.
• W3100102575 hasConcept C86803240 @default.
• W3100102575 hasConcept C89423630 @default.
• W3100102575 hasConcept C95444343 @default.
• W3100102575 hasConceptScore W3100102575C104317684 @default.
• W3100102575 hasConceptScore W3100102575C12554922 @default.
• W3100102575 hasConceptScore W3100102575C143065580 @default.
• W3100102575 hasConceptScore W3100102575C146587185 @default.
• W3100102575 hasConceptScore W3100102575C174618031 @default.
• W3100102575 hasConceptScore W3100102575C2776519988 @default.

• next