Matches in SemOpenAlex for { <https://semopenalex.org/work/W3100823141> ?p ?o ?g. }
- W3100823141 endingPage "103248" @default.
- W3100823141 startingPage "103248" @default.
- W3100823141 abstract "Resveratrol, a naturally synthesized polyphenolic compound found in some fruits, has anti neoplastic, anti-inflammatory, anti-oxidative, and anti-angiogenic properties. Angiogenesis is an important process in endometriosis which provides blood supply for implantation, proliferation and survival of endometriotic lesions. In this study, we assessed the effects of resveratrol on vascular endothelial growth factor (VEGF) and tumor necrosis factor alpha (TNF-α) expression in the eutopic endometrium of infertile patients with endometriosis within the window of implantation as a randomized exploratory trial. Subjects, who confirmed their endometriosis (stage III-IV) by a pathologist after laparoscopic surgery, were recruited to the present trial. A total of 34 patients were randomly divided into treatment (n = 17) and control (n = 17) groups, beside the routine protocol for treatment of endometriosis, they received resveratrol and placebo (400 mg) for 12-14 weeks, respectively. Endometrial tissue was collected from both groups before and after the intervention in the mid-secretory phase. Gene and protein expression levels of VEGF and TNF-α in the eutopic endometrium were assessed by Real-Time PCR and Western blotting, respectively. VEGF and TNF-α gene and protein levels in the treatment group showed significant decrease following intervention. It seems resveratrol may improve the endometrium of endometriosis patients in window of implantation period by modifying the expression of VEGF and TNF-α but further investigations are needed to reveal the potential role of this compound." @default.
- W3100823141 created "2020-11-23" @default.
- W3100823141 creator A5008713652 @default.
- W3100823141 creator A5012874154 @default.
- W3100823141 creator A5016716090 @default.
- W3100823141 creator A5028790023 @default.
- W3100823141 creator A5047759049 @default.
- W3100823141 creator A5051576513 @default.
- W3100823141 creator A5067526273 @default.
- W3100823141 creator A5071961237 @default.
- W3100823141 creator A5089296092 @default.
- W3100823141 creator A5091534393 @default.
- W3100823141 date "2021-02-01" @default.
- W3100823141 modified "2023-09-28" @default.
- W3100823141 title "A randomized exploratory trial to assess the effects of resveratrol on VEGF and TNF-α 2 expression in endometriosis women" @default.
- W3100823141 cites W1481670920 @default.
- W3100823141 cites W1510960970 @default.
- W3100823141 cites W1881147845 @default.
- W3100823141 cites W1978366541 @default.
- W3100823141 cites W1985765304 @default.
- W3100823141 cites W1987693231 @default.
- W3100823141 cites W2007451556 @default.
- W3100823141 cites W2013255457 @default.
- W3100823141 cites W2016599382 @default.
- W3100823141 cites W2025321452 @default.
- W3100823141 cites W2047955502 @default.
- W3100823141 cites W2067158566 @default.
- W3100823141 cites W2075846272 @default.
- W3100823141 cites W2084251750 @default.
- W3100823141 cites W2086233980 @default.
- W3100823141 cites W2098981439 @default.
- W3100823141 cites W2107277218 @default.
- W3100823141 cites W2109494575 @default.
- W3100823141 cites W2112165862 @default.
- W3100823141 cites W2115668011 @default.
- W3100823141 cites W2140246703 @default.
- W3100823141 cites W2158134092 @default.
- W3100823141 cites W2159069780 @default.
- W3100823141 cites W2169855351 @default.
- W3100823141 cites W2171356842 @default.
- W3100823141 cites W2204640292 @default.
- W3100823141 cites W2228733561 @default.
- W3100823141 cites W2230403972 @default.
- W3100823141 cites W2244373518 @default.
- W3100823141 cites W2487728522 @default.
- W3100823141 cites W2542453300 @default.
- W3100823141 cites W2558582132 @default.
- W3100823141 cites W2581250813 @default.
- W3100823141 cites W2607215535 @default.
- W3100823141 cites W2612556918 @default.
- W3100823141 cites W2802451887 @default.
- W3100823141 cites W2898855273 @default.
- W3100823141 cites W2913156404 @default.
- W3100823141 cites W2916508269 @default.
- W3100823141 cites W2943962155 @default.
- W3100823141 cites W3149429548 @default.
- W3100823141 cites W4211092896 @default.
- W3100823141 doi "https://doi.org/10.1016/j.jri.2020.103248" @default.
- W3100823141 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33387724" @default.
- W3100823141 hasPublicationYear "2021" @default.
- W3100823141 type Work @default.
- W3100823141 sameAs 3100823141 @default.
- W3100823141 citedByCount "23" @default.
- W3100823141 countsByYear W31008231412021 @default.
- W3100823141 countsByYear W31008231412022 @default.
- W3100823141 countsByYear W31008231412023 @default.
- W3100823141 crossrefType "journal-article" @default.
- W3100823141 hasAuthorship W3100823141A5008713652 @default.
- W3100823141 hasAuthorship W3100823141A5012874154 @default.
- W3100823141 hasAuthorship W3100823141A5016716090 @default.
- W3100823141 hasAuthorship W3100823141A5028790023 @default.
- W3100823141 hasAuthorship W3100823141A5047759049 @default.
- W3100823141 hasAuthorship W3100823141A5051576513 @default.
- W3100823141 hasAuthorship W3100823141A5067526273 @default.
- W3100823141 hasAuthorship W3100823141A5071961237 @default.
- W3100823141 hasAuthorship W3100823141A5089296092 @default.
- W3100823141 hasAuthorship W3100823141A5091534393 @default.
- W3100823141 hasConcept C126322002 @default.
- W3100823141 hasConcept C142724271 @default.
- W3100823141 hasConcept C16685009 @default.
- W3100823141 hasConcept C167734588 @default.
- W3100823141 hasConcept C17991360 @default.
- W3100823141 hasConcept C204787440 @default.
- W3100823141 hasConcept C27081682 @default.
- W3100823141 hasConcept C2776816829 @default.
- W3100823141 hasConcept C2777025900 @default.
- W3100823141 hasConcept C2779522080 @default.
- W3100823141 hasConcept C2779742232 @default.
- W3100823141 hasConcept C2780394083 @default.
- W3100823141 hasConcept C71924100 @default.
- W3100823141 hasConcept C98274493 @default.
- W3100823141 hasConceptScore W3100823141C126322002 @default.
- W3100823141 hasConceptScore W3100823141C142724271 @default.
- W3100823141 hasConceptScore W3100823141C16685009 @default.
- W3100823141 hasConceptScore W3100823141C167734588 @default.
- W3100823141 hasConceptScore W3100823141C17991360 @default.
- W3100823141 hasConceptScore W3100823141C204787440 @default.
- W3100823141 hasConceptScore W3100823141C27081682 @default.