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- W3111291214 abstract "<ns4:p><ns4:bold>Background:</ns4:bold> Coronavirus disease 2019 (COVID-19) is a global pandemic, which is associated with venous thromboembolism and pulmonary embolism (PE). This study aimed to estimate the pooled incidence of PE among patients hospitalized with COVID-19 within the published literature.</ns4:p><ns4:p> <ns4:bold>Methods:</ns4:bold> This systematic review and meta-analysis was performed according to PRISMA guidelines. An electronic search using MEDLINE /PubMed, ScienceDirect, Cochrane, and OpenGray databases was conducted May 19th, 2020. Search terms included COVID 19, SARS-CoV-2”, coronavirus disease 2019, 2019-nCoV, Wuhan coronavirus, “Pulmonary embolism”, pulmonary thromboembolism, “Pulmonary embol*”, “pulmonary thrombo*” and “PE”. Eligible studies included sufficient data to calculate the incidence of PE diagnosed during hospitalization in patients with COVID-19. Case reports were excluded. Quality was assessed using the Newcastle-Ottawa scale (observational cohort and case-control), AXIS tool (cross-sectional), and quality assessment tool (case series). Demographics and PE incidence data were extracted from the included studies and analyzed with R language. The pooled incidence of PE in patients hospitalized with COVID-19 was calculated.</ns4:p><ns4:p> <ns4:bold>Results:</ns4:bold> The database search identified 128 records. Ten observational studies were eligible and were included in the meta-analysis with a total of 1722 patients (mean age= 63.36). The pooled PE incidence in patients hospitalized with COVID-19 was 17% (95% CI: 0.1-0.26). There was a high degree of study heterogeneity (I2 = 94%, p<0.01).</ns4:p><ns4:p> <ns4:bold>Conclusion:</ns4:bold> The pooled PE incidence in patients hospitalized with COVID-19 is 17%. This increased incidence is greater than that previously reported in the general population of non-COVID-19. Attention and further investigation of this risk is warranted.</ns4:p>" @default.
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- W3111291214 date "2020-12-18" @default.
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- W3111291214 title "Incidence of acute pulmonary embolism among patients hospitalized with COVID-19: a systematic review and meta-analysis" @default.
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- W3111291214 doi "https://doi.org/10.12688/f1000research.27425.1" @default.
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