Matches in SemOpenAlex for { <https://semopenalex.org/work/W3129374908> ?p ?o ?g. }
- W3129374908 endingPage "119174" @default.
- W3129374908 startingPage "119174" @default.
- W3129374908 abstract "Functionalized hemodialysis membranes have been employed to suppress oxidative stress for hemodialysis therapy. However, the inhibition effects of the hemodialysis on the harmful metabolites of oxidative stress, including lipid peroxides and advanced glycation end products (AGEs), have not been fully explored yet. Herein, we report on utilizing the tannic acid (TA) coating as a reactive oxygen species (ROS) scavenger onto the hemodialysis membrane surface to solve this problem. Combining high biocompatibility of looped poly(2-ethyl-2-oxazoline) (PEtOx) brushes and anticoagulant property of heparin (Hep), the TA/PEtOx/Hep functionalized poly (ether sulfone) (PES) hemodialysis membrane has constructed by the nucleobase-recognized strategy. The functionalized membrane directly increased the serum total antioxidant capacity, and suppressed lipid peroxidation and protein glycosylation. The TA/PEtOx/Hep functionalized hemodialysis membrane effectively protected cardiomyocytes (H9C2) and vascular endothelial cells (HUVEC) from oxidative damage. The introduction of looped PEtOx brushes indicated in considerable improvement of blood compatibility and reduction of complement activation, and the immobilization of Hep prolonged the activated partial thromboplastin time. The typical toxins were removed in the simulation dialysis experiment, confirming the TA/PEtOx/Hep functionality feasibility. The present work provides a promising candidate for developing and applying the hemodialysis membrane, which might alleviate patients' complications to improve prognostic efficacy." @default.
- W3129374908 created "2021-03-01" @default.
- W3129374908 creator A5014708668 @default.
- W3129374908 creator A5022432177 @default.
- W3129374908 creator A5037989560 @default.
- W3129374908 creator A5077553763 @default.
- W3129374908 date "2021-05-01" @default.
- W3129374908 modified "2023-10-16" @default.
- W3129374908 title "Intervening oxidative stress integrated with an excellent biocompatibility of hemodialysis membrane fabricated by nucleobase-recognized co-immobilization strategy of tannic acid, looped PEtOx brush and heparin" @default.
- W3129374908 cites W142299751 @default.
- W3129374908 cites W1845346376 @default.
- W3129374908 cites W1932199148 @default.
- W3129374908 cites W1979643126 @default.
- W3129374908 cites W1979715009 @default.
- W3129374908 cites W1996878741 @default.
- W3129374908 cites W2009119278 @default.
- W3129374908 cites W2046357949 @default.
- W3129374908 cites W2049281887 @default.
- W3129374908 cites W2050867650 @default.
- W3129374908 cites W2051469879 @default.
- W3129374908 cites W2058340976 @default.
- W3129374908 cites W2060980725 @default.
- W3129374908 cites W2080978550 @default.
- W3129374908 cites W2085320052 @default.
- W3129374908 cites W2110596829 @default.
- W3129374908 cites W2122928767 @default.
- W3129374908 cites W2125317196 @default.
- W3129374908 cites W2138988352 @default.
- W3129374908 cites W2146611485 @default.
- W3129374908 cites W2147231830 @default.
- W3129374908 cites W2157501125 @default.
- W3129374908 cites W2322501303 @default.
- W3129374908 cites W2474247122 @default.
- W3129374908 cites W2508670332 @default.
- W3129374908 cites W2526769369 @default.
- W3129374908 cites W2527831315 @default.
- W3129374908 cites W2532657028 @default.
- W3129374908 cites W2535891667 @default.
- W3129374908 cites W2541184048 @default.
- W3129374908 cites W2567556174 @default.
- W3129374908 cites W2590412695 @default.
- W3129374908 cites W2607079712 @default.
- W3129374908 cites W2609940461 @default.
- W3129374908 cites W2613497245 @default.
- W3129374908 cites W2735158210 @default.
- W3129374908 cites W2741334054 @default.
- W3129374908 cites W2746405321 @default.
- W3129374908 cites W2761314670 @default.
- W3129374908 cites W2768866627 @default.
- W3129374908 cites W2776365893 @default.
- W3129374908 cites W2778478960 @default.
- W3129374908 cites W2795869461 @default.
- W3129374908 cites W2803702752 @default.
- W3129374908 cites W2804455498 @default.
- W3129374908 cites W2887184249 @default.
- W3129374908 cites W2891144711 @default.
- W3129374908 cites W2895589486 @default.
- W3129374908 cites W2903815267 @default.
- W3129374908 cites W2906159859 @default.
- W3129374908 cites W2907918058 @default.
- W3129374908 cites W2916013623 @default.
- W3129374908 cites W2939024126 @default.
- W3129374908 cites W2948689357 @default.
- W3129374908 cites W2971436651 @default.
- W3129374908 cites W2974215257 @default.
- W3129374908 cites W2977341508 @default.
- W3129374908 cites W2982251258 @default.
- W3129374908 cites W2983195649 @default.
- W3129374908 cites W2987503305 @default.
- W3129374908 cites W2988318375 @default.
- W3129374908 cites W3014071022 @default.
- W3129374908 cites W3023933256 @default.
- W3129374908 cites W3025020811 @default.
- W3129374908 cites W3036761446 @default.
- W3129374908 cites W3045257947 @default.
- W3129374908 cites W3085458131 @default.
- W3129374908 cites W958556329 @default.
- W3129374908 doi "https://doi.org/10.1016/j.memsci.2021.119174" @default.
- W3129374908 hasPublicationYear "2021" @default.
- W3129374908 type Work @default.
- W3129374908 sameAs 3129374908 @default.
- W3129374908 citedByCount "18" @default.
- W3129374908 countsByYear W31293749082021 @default.
- W3129374908 countsByYear W31293749082022 @default.
- W3129374908 countsByYear W31293749082023 @default.
- W3129374908 crossrefType "journal-article" @default.
- W3129374908 hasAuthorship W3129374908A5014708668 @default.
- W3129374908 hasAuthorship W3129374908A5022432177 @default.
- W3129374908 hasAuthorship W3129374908A5037989560 @default.
- W3129374908 hasAuthorship W3129374908A5077553763 @default.
- W3129374908 hasConcept C141071460 @default.
- W3129374908 hasConcept C178790620 @default.
- W3129374908 hasConcept C185592680 @default.
- W3129374908 hasConcept C2776151105 @default.
- W3129374908 hasConcept C2777230088 @default.
- W3129374908 hasConcept C2777557582 @default.
- W3129374908 hasConcept C2778063415 @default.
- W3129374908 hasConcept C2780829032 @default.