Matches in SemOpenAlex for { <https://semopenalex.org/work/W3129841807> ?p ?o ?g. }
- W3129841807 endingPage "294" @default.
- W3129841807 startingPage "294" @default.
- W3129841807 abstract "This study demonstrates how exposure to psychosocial crowding stress (CS) for 3, 7, and 14 days affects glutamate synapse functioning and signal transduction in the frontal cortex (FC) of rats. CS effects on synaptic activity were evaluated in FC slices of the primary motor cortex (M1) by measuring field potential (FP) amplitude, paired-pulse ratio (PPR), and long-term potentiation (LTP). Protein expression of GluA1, GluN2B mGluR1a/5, VGLUT1, and VGLUT2 was assessed in FC by western blot. The body’s response to CS was evaluated by measuring body weight and the plasma level of plasma corticosterone (CORT), adrenocorticotropic hormone (ACTH), and interleukin 1 beta (IL1B). CS 3 14d increased FP and attenuated LTP in M1, while PPR was augmented in CS 14d. The expression of GluA1, GluN2B, and mGluR1a/5 was up-regulated in CS 3d and downregulated in CS 14d. VGLUTs expression tended to increase in CS 7d. The failure to blunt the effects of chronic CS on FP and LTP in M1 suggests the impairment of habituation mechanisms by psychosocial stressors. PPR augmented by chronic CS with increased VGLUTs level in the CS 7d indicates that prolonged CS exposure changed presynaptic signaling within the FC. The CS bidirectional profile of changes in glutamate receptors’ expression seems to be a common mechanism evoked by stress in the FC." @default.
- W3129841807 created "2021-03-01" @default.
- W3129841807 creator A5004804122 @default.
- W3129841807 creator A5033535506 @default.
- W3129841807 creator A5044363360 @default.
- W3129841807 creator A5054801667 @default.
- W3129841807 creator A5058643666 @default.
- W3129841807 creator A5060725502 @default.
- W3129841807 creator A5065036145 @default.
- W3129841807 creator A5073568711 @default.
- W3129841807 creator A5074735117 @default.
- W3129841807 creator A5079268301 @default.
- W3129841807 date "2021-02-16" @default.
- W3129841807 modified "2023-10-03" @default.
- W3129841807 title "Psychosocial Crowding Stress-Induced Changes in Synaptic Transmission and Glutamate Receptor Expression in the Rat Frontal Cortex" @default.
- W3129841807 cites W1554082852 @default.
- W3129841807 cites W1594111906 @default.
- W3129841807 cites W1966931703 @default.
- W3129841807 cites W1972764647 @default.
- W3129841807 cites W1981102082 @default.
- W3129841807 cites W1991410461 @default.
- W3129841807 cites W1993536619 @default.
- W3129841807 cites W1995580496 @default.
- W3129841807 cites W1997008643 @default.
- W3129841807 cites W1997183808 @default.
- W3129841807 cites W1999772445 @default.
- W3129841807 cites W2009312694 @default.
- W3129841807 cites W2010530443 @default.
- W3129841807 cites W2012827629 @default.
- W3129841807 cites W2015420155 @default.
- W3129841807 cites W2016413199 @default.
- W3129841807 cites W2021290259 @default.
- W3129841807 cites W2023343746 @default.
- W3129841807 cites W2027241596 @default.
- W3129841807 cites W2028222586 @default.
- W3129841807 cites W2028540781 @default.
- W3129841807 cites W2032795396 @default.
- W3129841807 cites W2038293241 @default.
- W3129841807 cites W2041438725 @default.
- W3129841807 cites W2050871910 @default.
- W3129841807 cites W2063877829 @default.
- W3129841807 cites W2070005343 @default.
- W3129841807 cites W2074643409 @default.
- W3129841807 cites W2074796005 @default.
- W3129841807 cites W2093741677 @default.
- W3129841807 cites W2108446912 @default.
- W3129841807 cites W2108909652 @default.
- W3129841807 cites W2113167245 @default.
- W3129841807 cites W2115763058 @default.
- W3129841807 cites W2121446334 @default.
- W3129841807 cites W2128266752 @default.
- W3129841807 cites W2135321046 @default.
- W3129841807 cites W2146357663 @default.
- W3129841807 cites W2162681355 @default.
- W3129841807 cites W2171217262 @default.
- W3129841807 cites W2225324288 @default.
- W3129841807 cites W2274459527 @default.
- W3129841807 cites W2290814287 @default.
- W3129841807 cites W2302657539 @default.
- W3129841807 cites W2332324740 @default.
- W3129841807 cites W2413515606 @default.
- W3129841807 cites W2462050595 @default.
- W3129841807 cites W2508688213 @default.
- W3129841807 cites W2515284988 @default.
- W3129841807 cites W2604480906 @default.
- W3129841807 cites W2611574096 @default.
- W3129841807 cites W2777987555 @default.
- W3129841807 cites W2795786462 @default.
- W3129841807 cites W2801449365 @default.
- W3129841807 cites W2807318413 @default.
- W3129841807 cites W2911753026 @default.
- W3129841807 cites W2936399695 @default.
- W3129841807 doi "https://doi.org/10.3390/biom11020294" @default.
- W3129841807 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7920072" @default.
- W3129841807 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33669305" @default.
- W3129841807 hasPublicationYear "2021" @default.
- W3129841807 type Work @default.
- W3129841807 sameAs 3129841807 @default.
- W3129841807 citedByCount "3" @default.
- W3129841807 countsByYear W31298418072022 @default.
- W3129841807 countsByYear W31298418072023 @default.
- W3129841807 crossrefType "journal-article" @default.
- W3129841807 hasAuthorship W3129841807A5004804122 @default.
- W3129841807 hasAuthorship W3129841807A5033535506 @default.
- W3129841807 hasAuthorship W3129841807A5044363360 @default.
- W3129841807 hasAuthorship W3129841807A5054801667 @default.
- W3129841807 hasAuthorship W3129841807A5058643666 @default.
- W3129841807 hasAuthorship W3129841807A5060725502 @default.
- W3129841807 hasAuthorship W3129841807A5065036145 @default.
- W3129841807 hasAuthorship W3129841807A5073568711 @default.
- W3129841807 hasAuthorship W3129841807A5074735117 @default.
- W3129841807 hasAuthorship W3129841807A5079268301 @default.
- W3129841807 hasBestOaLocation W31298418071 @default.
- W3129841807 hasConcept C112592302 @default.
- W3129841807 hasConcept C126322002 @default.
- W3129841807 hasConcept C134018914 @default.
- W3129841807 hasConcept C148762608 @default.
- W3129841807 hasConcept C15744967 @default.