FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3140256074> ?p ?o ?g. }

• W3140256074 abstract "Stromal elastosis is related to good prognosis in breast cancer and fibulin-2 helps to stabilize elastic fibers in basement membranes. Here, we examined the level of perivascular fibulin-2 expression in relation to elastosis content, vascular invasion, molecular subtypes, tumour detection mode, and patient prognosis in breast cancer. We performed a population based retrospective study of invasive breast cancers from the Norwegian Breast Screening Program (Vestfold County, 2004–2009) including 200 screen-detected and 82 interval cancers. Perivascular fibulin-2 staining was semi-quantitatively graded based on immunohistochemistry (1–3) and dichotomized as high expression (grade 2–3) and low expression (grade 1). Elastosis content was graded on a 4-tiered scale and dichotomized as high (score 3) and low (score 0–2) expression, whereas lymphatic (LVI) and blood vessel invasion (BVI) were recorded as absent or present by immunohistochemistry. High perivascular fibulin-2 expression was strongly related to stromal elastosis (p<0.001), and inversely associated with BVI and LVI (p<0.001 for both). High fibulin-2 was associated with luminal breast cancer subgroups (p<0.001) and inversely with interval cancers compared with screen-detected tumours (p<0.001). By univariate analysis, low perivascular fibulin-2 was associated with reduced recurrence-free survival (p = 0.002) and disease specific survival (p = 0.019). Low perivascular fibulin-2 expression was strongly related to vascular invasion, low stromal elastosis, non-luminal breast cancer subtypes, interval presentation, and adverse prognosis." @default.
• W3140256074 created "2021-04-13" @default.
• W3140256074 creator A5034612779 @default.
• W3140256074 creator A5040558103 @default.
• W3140256074 creator A5048803111 @default.
• W3140256074 creator A5068445062 @default.
• W3140256074 creator A5075089626 @default.
• W3140256074 date "2021-04-09" @default.
• W3140256074 modified "2023-09-24" @default.
• W3140256074 title "Fibulin-2 expression associates with vascular invasion and patient survival in breast cancer" @default.
• W3140256074 cites W1890402826 @default.
• W3140256074 cites W1963855416 @default.
• W3140256074 cites W1964229346 @default.
• W3140256074 cites W1997756362 @default.
• W3140256074 cites W2008687978 @default.
• W3140256074 cites W2018773400 @default.
• W3140256074 cites W2034855589 @default.
• W3140256074 cites W2044545967 @default.
• W3140256074 cites W2045371528 @default.
• W3140256074 cites W2068673065 @default.
• W3140256074 cites W2085521719 @default.
• W3140256074 cites W2094271277 @default.
• W3140256074 cites W2102161352 @default.
• W3140256074 cites W2106090241 @default.
• W3140256074 cites W2107089660 @default.
• W3140256074 cites W2108270268 @default.
• W3140256074 cites W2108362435 @default.
• W3140256074 cites W2109759501 @default.
• W3140256074 cites W2115124692 @default.
• W3140256074 cites W2117775530 @default.
• W3140256074 cites W2130067006 @default.
• W3140256074 cites W2156634381 @default.
• W3140256074 cites W2171408325 @default.
• W3140256074 cites W2342018381 @default.
• W3140256074 cites W2724386187 @default.
• W3140256074 cites W2891648096 @default.
• W3140256074 doi "https://doi.org/10.1371/journal.pone.0249767" @default.
• W3140256074 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8034712" @default.
• W3140256074 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33836007" @default.
• W3140256074 hasPublicationYear "2021" @default.
• W3140256074 type Work @default.
• W3140256074 sameAs 3140256074 @default.
• W3140256074 citedByCount "1" @default.
• W3140256074 countsByYear W31402560742022 @default.
• W3140256074 crossrefType "journal-article" @default.
• W3140256074 hasAuthorship W3140256074A5034612779 @default.
• W3140256074 hasAuthorship W3140256074A5040558103 @default.
• W3140256074 hasAuthorship W3140256074A5048803111 @default.
• W3140256074 hasAuthorship W3140256074A5068445062 @default.
• W3140256074 hasAuthorship W3140256074A5075089626 @default.
• W3140256074 hasBestOaLocation W31402560741 @default.
• W3140256074 hasConcept C121608353 @default.
• W3140256074 hasConcept C126322002 @default.
• W3140256074 hasConcept C142724271 @default.
• W3140256074 hasConcept C143998085 @default.
• W3140256074 hasConcept C144301174 @default.
• W3140256074 hasConcept C16930146 @default.
• W3140256074 hasConcept C189165786 @default.
• W3140256074 hasConcept C204232928 @default.
• W3140256074 hasConcept C2778122751 @default.
• W3140256074 hasConcept C2778740770 @default.
• W3140256074 hasConcept C2779013556 @default.
• W3140256074 hasConcept C2779869378 @default.
• W3140256074 hasConcept C38180746 @default.
• W3140256074 hasConcept C530470458 @default.
• W3140256074 hasConcept C71924100 @default.
• W3140256074 hasConcept C86803240 @default.
• W3140256074 hasConcept C95444343 @default.
• W3140256074 hasConceptScore W3140256074C121608353 @default.
• W3140256074 hasConceptScore W3140256074C126322002 @default.
• W3140256074 hasConceptScore W3140256074C142724271 @default.
• W3140256074 hasConceptScore W3140256074C143998085 @default.
• W3140256074 hasConceptScore W3140256074C144301174 @default.
• W3140256074 hasConceptScore W3140256074C16930146 @default.
• W3140256074 hasConceptScore W3140256074C189165786 @default.
• W3140256074 hasConceptScore W3140256074C204232928 @default.
• W3140256074 hasConceptScore W3140256074C2778122751 @default.
• W3140256074 hasConceptScore W3140256074C2778740770 @default.
• W3140256074 hasConceptScore W3140256074C2779013556 @default.
• W3140256074 hasConceptScore W3140256074C2779869378 @default.
• W3140256074 hasConceptScore W3140256074C38180746 @default.
• W3140256074 hasConceptScore W3140256074C530470458 @default.
• W3140256074 hasConceptScore W3140256074C71924100 @default.
• W3140256074 hasConceptScore W3140256074C86803240 @default.
• W3140256074 hasConceptScore W3140256074C95444343 @default.
• W3140256074 hasLocation W31402560741 @default.
• W3140256074 hasLocation W31402560742 @default.
• W3140256074 hasLocation W31402560743 @default.
• W3140256074 hasLocation W31402560744 @default.
• W3140256074 hasOpenAccess W3140256074 @default.
• W3140256074 hasPrimaryLocation W31402560741 @default.
• W3140256074 hasRelatedWork W1810920307 @default.
• W3140256074 hasRelatedWork W2013199537 @default.
• W3140256074 hasRelatedWork W2097534329 @default.
• W3140256074 hasRelatedWork W2412122492 @default.
• W3140256074 hasRelatedWork W2473120957 @default.
• W3140256074 hasRelatedWork W2576774687 @default.
• W3140256074 hasRelatedWork W2892287597 @default.
• W3140256074 hasRelatedWork W2966753069 @default.
• W3140256074 hasRelatedWork W3160736738 @default.

• next