FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3145688314> ?p ?o ?g. }

• W3145688314 endingPage "5397" @default.
• W3145688314 startingPage "5394" @default.
• W3145688314 abstract "The anti-arrhythmic agent amiodarone (AD) is associated with numerous adverse effects, but serious liver disease is rare. The improved safety of administration of daily low doses of AD has already been established and this regimen is used for long-term medication. Nevertheless,asymptomatic continuous liver injury by AD may increase the risk of step-wise progression of non-alcoholic fatty liver disease. We present an autopsy case of AD-induced liver cirrhosis in a patient who had been treated with a low dose of AD (200 mg/d) daily for 84 mo. The patient was a 85-year-old male with a history of ischemic heart disease.Seven years after initiation of treatment with AD, he was admitted with cardiac congestion. The total dose of AD was 528 g. Mild elevation of serum aminotransferase and hepatomegaly were present. Liver biopsy specimens revealed cirrhosis, and under electron microscopy numerous lysosomes with electron-dense, whorled, lamellar inclusions characteristic of a secondary phospholipidosis were observed. Initially, withdrawal of AD led to a slight improvement of serum aminotransferase levels, but unfortunately his general condition deteriorated and he died from complications of pneumonia and renal failure.Long-term administration of daily low doses of AD carries the risk of progression to irreversible liver injury. Therefore,periodic examination of liver function and/or liver biopsy is required for the management of patients receiving long-term treatment with AD." @default.
• W3145688314 created "2021-04-13" @default.
• W3145688314 creator A5001209541 @default.
• W3145688314 creator A5003252408 @default.
• W3145688314 creator A5012900777 @default.
• W3145688314 creator A5013148811 @default.
• W3145688314 creator A5022232898 @default.
• W3145688314 creator A5029927266 @default.
• W3145688314 creator A5030332362 @default.
• W3145688314 creator A5030715997 @default.
• W3145688314 creator A5032407231 @default.
• W3145688314 creator A5033789628 @default.
• W3145688314 creator A5034866944 @default.
• W3145688314 creator A5037907587 @default.
• W3145688314 creator A5043457676 @default.
• W3145688314 creator A5049369806 @default.
• W3145688314 creator A5061022620 @default.
• W3145688314 creator A5068278353 @default.
• W3145688314 creator A5068278524 @default.
• W3145688314 creator A5069647051 @default.
• W3145688314 creator A5087129328 @default.
• W3145688314 date "2005-01-01" @default.
• W3145688314 modified "2023-09-24" @default.
• W3145688314 title "Liver cirrhosis induced by long-term administration of a daily low dose of amiodarone： A case report" @default.
• W3145688314 hasPublicationYear "2005" @default.
• W3145688314 type Work @default.
• W3145688314 sameAs 3145688314 @default.
• W3145688314 citedByCount "0" @default.
• W3145688314 crossrefType "journal-article" @default.
• W3145688314 hasAuthorship W3145688314A5001209541 @default.
• W3145688314 hasAuthorship W3145688314A5003252408 @default.
• W3145688314 hasAuthorship W3145688314A5012900777 @default.
• W3145688314 hasAuthorship W3145688314A5013148811 @default.
• W3145688314 hasAuthorship W3145688314A5022232898 @default.
• W3145688314 hasAuthorship W3145688314A5029927266 @default.
• W3145688314 hasAuthorship W3145688314A5030332362 @default.
• W3145688314 hasAuthorship W3145688314A5030715997 @default.
• W3145688314 hasAuthorship W3145688314A5032407231 @default.
• W3145688314 hasAuthorship W3145688314A5033789628 @default.
• W3145688314 hasAuthorship W3145688314A5034866944 @default.
• W3145688314 hasAuthorship W3145688314A5037907587 @default.
• W3145688314 hasAuthorship W3145688314A5043457676 @default.
• W3145688314 hasAuthorship W3145688314A5049369806 @default.
• W3145688314 hasAuthorship W3145688314A5061022620 @default.
• W3145688314 hasAuthorship W3145688314A5068278353 @default.
• W3145688314 hasAuthorship W3145688314A5068278524 @default.
• W3145688314 hasAuthorship W3145688314A5069647051 @default.
• W3145688314 hasAuthorship W3145688314A5087129328 @default.
• W3145688314 hasConcept C126322002 @default.
• W3145688314 hasConcept C142724271 @default.
• W3145688314 hasConcept C197934379 @default.
• W3145688314 hasConcept C2775934546 @default.
• W3145688314 hasConcept C2776637226 @default.
• W3145688314 hasConcept C2777075537 @default.
• W3145688314 hasConcept C2777214474 @default.
• W3145688314 hasConcept C2777766500 @default.
• W3145688314 hasConcept C2777910003 @default.
• W3145688314 hasConcept C2778094803 @default.
• W3145688314 hasConcept C2778772119 @default.
• W3145688314 hasConcept C2778918659 @default.
• W3145688314 hasConcept C2779134260 @default.
• W3145688314 hasConcept C2779161974 @default.
• W3145688314 hasConcept C2779934242 @default.
• W3145688314 hasConcept C2992208098 @default.
• W3145688314 hasConcept C41625074 @default.
• W3145688314 hasConcept C512861765 @default.
• W3145688314 hasConcept C54355233 @default.
• W3145688314 hasConcept C71924100 @default.
• W3145688314 hasConcept C86803240 @default.
• W3145688314 hasConcept C90924648 @default.
• W3145688314 hasConceptScore W3145688314C126322002 @default.
• W3145688314 hasConceptScore W3145688314C142724271 @default.
• W3145688314 hasConceptScore W3145688314C197934379 @default.
• W3145688314 hasConceptScore W3145688314C2775934546 @default.
• W3145688314 hasConceptScore W3145688314C2776637226 @default.
• W3145688314 hasConceptScore W3145688314C2777075537 @default.
• W3145688314 hasConceptScore W3145688314C2777214474 @default.
• W3145688314 hasConceptScore W3145688314C2777766500 @default.
• W3145688314 hasConceptScore W3145688314C2777910003 @default.
• W3145688314 hasConceptScore W3145688314C2778094803 @default.
• W3145688314 hasConceptScore W3145688314C2778772119 @default.
• W3145688314 hasConceptScore W3145688314C2778918659 @default.
• W3145688314 hasConceptScore W3145688314C2779134260 @default.
• W3145688314 hasConceptScore W3145688314C2779161974 @default.
• W3145688314 hasConceptScore W3145688314C2779934242 @default.
• W3145688314 hasConceptScore W3145688314C2992208098 @default.
• W3145688314 hasConceptScore W3145688314C41625074 @default.
• W3145688314 hasConceptScore W3145688314C512861765 @default.
• W3145688314 hasConceptScore W3145688314C54355233 @default.
• W3145688314 hasConceptScore W3145688314C71924100 @default.
• W3145688314 hasConceptScore W3145688314C86803240 @default.
• W3145688314 hasConceptScore W3145688314C90924648 @default.
• W3145688314 hasIssue "34" @default.
• W3145688314 hasLocation W31456883141 @default.
• W3145688314 hasOpenAccess W3145688314 @default.
• W3145688314 hasPrimaryLocation W31456883141 @default.
• W3145688314 hasRelatedWork W106123568 @default.
• W3145688314 hasRelatedWork W1483222848 @default.

• next